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Murcko scaffold

Ring system with 3 rings and 29 atoms

10 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
29
Chemicals
10
With full pages
4
Scaffold SMILES

O=C(NC(CCNS(=O)(=O)c1ccccc1)Cc1ccccc1)OC1CCOC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC(CCNS(=O)(=O)c1ccccc1)Cc1ccccc1)OC1CCOC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Amprenavir chemical structure, C25H35N3O6S, CAS 161814-49-9
Amprenavir
CAS 161814-49-9C25H35N3O6S
Fosamprenavir calcium chemical structure, C25H34CaN3O9PS, CAS 226700-81-8
Fosamprenavir calcium
CAS 226700-81-8C25H34CaN3O9PS
Fosamprenavir chemical structure, C25H36N3O9PS, CAS 226700-79-4
Fosamprenavir
CAS 226700-79-4C25H36N3O9PS
Fosamprenavir sodium chemical structure, C25H34N3Na2O9PS, CAS 226700-80-7
Fosamprenavir sodium
CAS 226700-80-7C25H34N3Na2O9PS
(3S)-Tetrahydro-3-furanyl N-((1S,2R)-2-hydroxy-3-((2-methylpropyl)((4-nitrophenyl)sulfonyl)amino)-1-(phenylmethyl)propyl)carbamate chemical structure, C25H33N3O8S, CAS 160231-69-6
(3S)-Tetrahydro-3-furanyl N-((1S,2R)-2-hydroxy-3-((2-methylpropyl)((4-nitrophenyl)sulfonyl)amino)-1-(phenylmethyl)propyl)carbamate
CAS 160231-69-6C25H33N3O8S
(S)-Tetrahydrofuran-3-yl(2S,3R)-4-(N-isobutyl-4-nitrophenyl sulfonamido)-1-phenyl-3-(phosphonooxy)butan-2-yl-carbamate chemical structure, C25H34N3O11PS, CAS 229495-87-8
(S)-Tetrahydrofuran-3-yl(2S,3R)-4-(N-isobutyl-4-nitrophenyl sulfonamido)-1-phenyl-3-(phosphonooxy)butan-2-yl-carbamate
CAS 229495-87-8C25H34N3O11PS
Amprenavir-d4 chemical structure, C25H35N3O6S, CAS 1217661-20-5
Amprenavir-d4
CAS 1217661-20-5C25H35N3O6S
[(1S,2R)-3-[[(4-Nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-phenylmethyl)propyl]carbamic Acid, (3S)-Tetrahydro-3-furan-d4-yl Ester chemical structure, C25H33N3O8S, CAS 1217700-81-6
[(1S,2R)-3-[[(4-Nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-phenylmethyl)propyl]carbamic Acid, (3S)-Tetrahydro-3-furan-d4-yl Ester
CAS 1217700-81-6C25H33N3O8S
(R)-Tetrahydrofuran-3-yl ((2R,3S)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate chemical structure, C25H35N3O6S, CAS 187946-08-3
(R)-Tetrahydrofuran-3-yl ((2R,3S)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate
CAS 187946-08-3C25H35N3O6S
Amprenavir-d4-1 chemical structure, C25H35N3O6S, CAS 2738376-78-6
Amprenavir-d4-1
CAS 2738376-78-6C25H35N3O6S