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Murcko scaffold

N-(2,6-Dioxopiperidin-3-yl)benzamide scaffold

85 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 17
Chemicals: 85
With full pages: 4

Scaffold SMILES

O=C1CCC(NC(=O)c2ccccc2)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-(2,6-Dioxopiperidin-3-yl)benzamide page

Murcko scaffold O=C1CCC(NC(=O)c2ccccc2)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 85 of 85 chemicals

3-Chloro-N-(2,6-dioxopiperidin-3-yl)benzamide chemical structure, C12H11ClN2O3, CAS 194712-29-3

3-Chloro-N-(2,6-dioxopiperidin-3-yl)benzamide

CAS 194712-29-3C₁₂H₁₁ClN₂O₃

3-Amino-2-[[(2,6-dioxo-3-piperidinyl)amino]carbonyl]benzoic Acid chemical structure, C13H13N3O5, CAS 1001852-15-8

3-Amino-2-[[(2,6-dioxo-3-piperidinyl)amino]carbonyl]benzoic Acid

CAS 1001852-15-8C₁₃H₁₃N₃O₅

Benzoic acid,2-[[(2,6-dioxo-3-piperidinyl)amino]carbonyl]-3-nitro- chemical structure, C13H11N3O7, CAS 1001852-10-3

Benzoic acid,2-[[(2,6-dioxo-3-piperidinyl)amino]carbonyl]-3-nitro-

CAS 1001852-10-3C₁₃H₁₁N₃O₇

4-Bromo-N-(2,6-dioxopiperidin-3-yl)-2,6-difluorobenzamide chemical structure, C12H9BrF2N2O3, CAS 1516212-78-4

4-Bromo-N-(2,6-dioxopiperidin-3-yl)-2,6-difluorobenzamide

CAS 1516212-78-4C₁₂H₉BrF₂N₂O₃

3-Chloro-N-(2,6-dioxopiperidin-3-yl)-2-fluorobenzamide chemical structure, C12H10ClFN2O3, CAS 1536814-65-9

3-Chloro-N-(2,6-dioxopiperidin-3-yl)-2-fluorobenzamide

CAS 1536814-65-9C₁₂H₁₀ClFN₂O₃

3-Chloro-N-(2,6-dioxopiperidin-3-yl)-5-methylbenzamide chemical structure, C13H13ClN2O3, CAS 1540692-84-9

3-Chloro-N-(2,6-dioxopiperidin-3-yl)-5-methylbenzamide

CAS 1540692-84-9C₁₃H₁₃ClN₂O₃

4-Amino-N-(2,6-dioxo-3-piperidinyl)-2-methoxyBenzamide chemical structure, C13H15N3O4, CAS 1504209-32-8

4-Amino-N-(2,6-dioxo-3-piperidinyl)-2-methoxyBenzamide

CAS 1504209-32-8C₁₃H₁₅N₃O₄

2-Acetamido-N-(2,6-dioxopiperidin-3-yl)-6-nitrobenzamide chemical structure, C14H14N4O6, CAS 1620018-94-1

2-Acetamido-N-(2,6-dioxopiperidin-3-yl)-6-nitrobenzamide

CAS 1620018-94-1C₁₄H₁₄N₄O₆

N-(2,6-dioxo-3-piperidinyl)-2,6-dimethylBenzamide chemical structure, C14H16N2O3, CAS 1910987-28-8

N-(2,6-dioxo-3-piperidinyl)-2,6-dimethylBenzamide

CAS 1910987-28-8C₁₄H₁₆N₂O₃

4-Chloro-N-(2,6-dioxopiperidin-3-yl)-3-fluorobenzamide chemical structure, C12H10ClFN2O3, CAS 1911120-95-0

4-Chloro-N-(2,6-dioxopiperidin-3-yl)-3-fluorobenzamide

CAS 1911120-95-0C₁₂H₁₀ClFN₂O₃

E3 ligase Ligand 49 chemical structure, C13H15N3O4, CAS 1911013-66-5

E3 ligase Ligand 49

CAS 1911013-66-5C₁₃H₁₅N₃O₄

4-Chloro-N-(2,6-dioxopiperidin-3-yl)-3-methylbenzamide chemical structure, C13H13ClN2O3, CAS 1706546-05-5

4-Chloro-N-(2,6-dioxopiperidin-3-yl)-3-methylbenzamide

CAS 1706546-05-5C₁₃H₁₃ClN₂O₃

3-Chloro-N-(2,6-dioxopiperidin-3-yl)-2-nitrobenzamide chemical structure, C12H10ClN3O5, CAS 1544017-53-9

3-Chloro-N-(2,6-dioxopiperidin-3-yl)-2-nitrobenzamide

CAS 1544017-53-9C₁₂H₁₀ClN₃O₅

3-Chloro-N-(2,6-dioxopiperidin-3-yl)-4-fluorobenzamide chemical structure, C12H10ClFN2O3, CAS 1543937-31-0

3-Chloro-N-(2,6-dioxopiperidin-3-yl)-4-fluorobenzamide

CAS 1543937-31-0C₁₂H₁₀ClFN₂O₃

3-(Aminomethyl)-N-(2,6-dioxopiperidin-3-yl)benzamide hydrochloride chemical structure, C13H16ClN3O3, CAS 2173996-40-0

3-(Aminomethyl)-N-(2,6-dioxopiperidin-3-yl)benzamide hydrochloride

CAS 2173996-40-0C₁₃H₁₆ClN₃O₃

N-(2,6-Dioxopiperidin-3-yl)-N-methyl-3-(trifluoromethoxy)benzamide chemical structure, C14H13F3N2O4, CAS 2154340-07-3

N-(2,6-Dioxopiperidin-3-yl)-N-methyl-3-(trifluoromethoxy)benzamide

CAS 2154340-07-3C₁₄H₁₃F₃N₂O₄

N-(2,6-Dioxopiperidin-3-yl)-2-hydroxy-N-methylbenzamide chemical structure, C13H14N2O4, CAS 2154339-86-1

N-(2,6-Dioxopiperidin-3-yl)-2-hydroxy-N-methylbenzamide

CAS 2154339-86-1C₁₃H₁₄N₂O₄

N-(2,6-Dioxopiperidin-3-yl)-2,6-difluoro-N-methylbenzamide chemical structure, C13H12F2N2O3, CAS 2154340-65-3

N-(2,6-Dioxopiperidin-3-yl)-2,6-difluoro-N-methylbenzamide

CAS 2154340-65-3C₁₃H₁₂F₂N₂O₃

N-(2,6-Dioxopiperidin-3-yl)-3,5-dimethoxy-N-methylbenzamide chemical structure, C15H18N2O5, CAS 2154340-17-5

N-(2,6-Dioxopiperidin-3-yl)-3,5-dimethoxy-N-methylbenzamide

CAS 2154340-17-5C₁₅H₁₈N₂O₅

N-(2,6-Dioxopiperidin-3-yl)-2-fluoro-5-methoxy-N-methylbenzamide chemical structure, C14H15FN2O4, CAS 2154340-27-7

N-(2,6-Dioxopiperidin-3-yl)-2-fluoro-5-methoxy-N-methylbenzamide

CAS 2154340-27-7C₁₄H₁₅FN₂O₄

N-(2,6-Dioxopiperidin-3-yl)-2-fluoro-3-methoxy-N-methylbenzamide chemical structure, C14H15FN2O4, CAS 2154339-65-6

N-(2,6-Dioxopiperidin-3-yl)-2-fluoro-3-methoxy-N-methylbenzamide

CAS 2154339-65-6C₁₄H₁₅FN₂O₄

2-Cyano-N-(2,6-dioxopiperidin-3-yl)-N-methylbenzamide chemical structure, C14H13N3O3, CAS 2154339-91-8

2-Cyano-N-(2,6-dioxopiperidin-3-yl)-N-methylbenzamide

CAS 2154339-91-8C₁₄H₁₃N₃O₃

4-Cyano-N-(2,6-dioxopiperidin-3-yl)-N-methylbenzamide chemical structure, C14H13N3O3, CAS 2154340-50-6

4-Cyano-N-(2,6-dioxopiperidin-3-yl)-N-methylbenzamide

CAS 2154340-50-6C₁₄H₁₃N₃O₃

4-Bromo-N-(2,6-dioxo-3-piperidinyl)-N-methylBenzamide chemical structure, C13H13BrN2O3, CAS 2154339-51-0

4-Bromo-N-(2,6-dioxo-3-piperidinyl)-N-methylBenzamide

CAS 2154339-51-0C₁₃H₁₃BrN₂O₃