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Murcko scaffold

Ring system with 3 rings and 21 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
8
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(NC(=O)C2CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc(NC(=O)C2CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

2-[({4-[(Cyclopropylcarbonyl)amino]phenyl}carbonyl)amino]benzoic acid chemical structure, C18H16N2O4, CAS 666711-16-6
2-[({4-[(Cyclopropylcarbonyl)amino]phenyl}carbonyl)amino]benzoic acid
CAS 666711-16-6C18H16N2O4
4-(Cyclopropanecarbonylamino)-N-(2-ethoxyphenyl)benzamide chemical structure, C19H20N2O3, CAS 847571-97-5
4-(Cyclopropanecarbonylamino)-N-(2-ethoxyphenyl)benzamide
CAS 847571-97-5C19H20N2O3
N-(2-Methoxyphenyl)-4-[(2-methylcyclopropanecarbonyl)amino]benzamide chemical structure, C19H20N2O3, CAS 794580-70-4
N-(2-Methoxyphenyl)-4-[(2-methylcyclopropanecarbonyl)amino]benzamide
CAS 794580-70-4C19H20N2O3
{4-[({4-[(Cyclopropylcarbonyl)amino]phenyl}carbonyl)amino]phenyl}acetic acid chemical structure, C19H18N2O4, CAS 891008-04-1
{4-[({4-[(Cyclopropylcarbonyl)amino]phenyl}carbonyl)amino]phenyl}acetic acid
CAS 891008-04-1C19H18N2O4
4-(Cyclopropanecarbonylamino)-N-(2-hydroxyphenyl)benzamide chemical structure, C17H16N2O3, CAS 891008-75-6
4-(Cyclopropanecarbonylamino)-N-(2-hydroxyphenyl)benzamide
CAS 891008-75-6C17H16N2O3
4-[(Cyclopropylcarbonyl)amino]-N-ethyl-N-phenylbenzamide chemical structure, C19H20N2O2, CAS 941422-54-4
4-[(Cyclopropylcarbonyl)amino]-N-ethyl-N-phenylbenzamide
CAS 941422-54-4C19H20N2O2
4-[(Cyclopropylcarbonyl)amino]-N-methyl-N-phenylbenzamide chemical structure, C18H18N2O2, CAS 923746-96-7
4-[(Cyclopropylcarbonyl)amino]-N-methyl-N-phenylbenzamide
CAS 923746-96-7C18H18N2O2
4-[(Cyclopropylcarbonyl)amino]-N-(2,5-dimethoxyphenyl)benzamide chemical structure, C19H20N2O4, CAS 899288-09-6
4-[(Cyclopropylcarbonyl)amino]-N-(2,5-dimethoxyphenyl)benzamide
CAS 899288-09-6C19H20N2O4