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Murcko scaffold

Ring system with 3 rings and 22 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
4
With full pages
4
Scaffold SMILES

O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)C1CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)C1CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)cyclopropanecarboxamide chemical structure, C16H18N4O3S, CAS 433691-75-9
N-(4-{[(4,6-Dimethyl-2-pyrimidinyl)amino]sulfonyl}phenyl)cyclopropanecarboxamide
CAS 433691-75-9C16H18N4O3S
N-[4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl]cyclopropanecarboxamide chemical structure, C15H16N4O3S, CAS 549477-99-8
N-[4-[(4-Methylpyrimidin-2-yl)sulfamoyl]phenyl]cyclopropanecarboxamide
CAS 549477-99-8C15H16N4O3S
3-(2,2-Dichloroethenyl)-2,2-dimethyl-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}cyclopropane-1-carboxamide chemical structure, C18H18Cl2N4O3S, CAS 364384-20-3
3-(2,2-Dichloroethenyl)-2,2-dimethyl-N-{4-[(pyrimidin-2-yl)sulfamoyl]phenyl}cyclopropane-1-carboxamide
CAS 364384-20-3C18H18Cl2N4O3S
3-(2,2-Dichloroethenyl)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2,2-dimethylcyclopropane-1-carboxamide chemical structure, C20H22Cl2N4O3S, CAS 297146-33-9
3-(2,2-Dichloroethenyl)-N-{4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-2,2-dimethylcyclopropane-1-carboxamide
CAS 297146-33-9C20H22Cl2N4O3S