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Murcko scaffold

Ring system with 3 rings and 19 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
16
With full pages
8
Scaffold SMILES

S=c1[nH]nc(-c2cc[nH]n2)n1N=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(-c2cc[nH]n2)n1N=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

4-({[4-(Diethylamino)phenyl]methylidene}amino)-5-(5-methyl-1H-pyrazol-3-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C17H21N7S, CAS 4809-04-5
4-({[4-(Diethylamino)phenyl]methylidene}amino)-5-(5-methyl-1H-pyrazol-3-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione
CAS 4809-04-5C17H21N7S
4-{[(E)-(2-Methoxyphenyl)methylidene]amino}-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C14H14N6OS, CAS 1037560-98-7
4-{[(E)-(2-Methoxyphenyl)methylidene]amino}-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1037560-98-7C14H14N6OS
4-{[(E)-(4-Chloro-3-nitrophenyl)methylidene]amino}-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H10ClN7O2S, CAS 1035066-95-5
4-{[(E)-(4-Chloro-3-nitrophenyl)methylidene]amino}-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1035066-95-5C13H10ClN7O2S
4-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C15H16N6O2S, CAS 1035963-40-6
4-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione
CAS 1035963-40-6C15H16N6O2S
4-[(E)-(4-Methoxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C14H14N6OS, CAS 850737-50-7
4-[(E)-(4-Methoxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione
CAS 850737-50-7C14H14N6OS
(E)-4-((5-Bromo-2-fluorobenzylidene)amino)-5-(3-methyl-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H10BrFN6S, CAS 1037558-11-4
(E)-4-((5-Bromo-2-fluorobenzylidene)amino)-5-(3-methyl-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol
CAS 1037558-11-4C13H10BrFN6S
4-{[(E)-(3-Fluorophenyl)methylidene]amino}-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H11FN6S, CAS 1037560-84-1
4-{[(E)-(3-Fluorophenyl)methylidene]amino}-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1037560-84-1C13H11FN6S
5-(5-Methyl-1H-pyrazol-3-yl)-4-({(E)-[4-(methylsulfanyl)phenyl]methylidene}amino)-4H-1,2,4-triazole-3-thiol chemical structure, C14H14N6S2, CAS 1037585-08-2
5-(5-Methyl-1H-pyrazol-3-yl)-4-({(E)-[4-(methylsulfanyl)phenyl]methylidene}amino)-4H-1,2,4-triazole-3-thiol
CAS 1037585-08-2C14H14N6S2
4-[(E)-(3-Hydroxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H12N6OS, CAS 850242-80-7
4-[(E)-(3-Hydroxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione
CAS 850242-80-7C13H12N6OS
4-[(E)-(3-Methoxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C14H14N6OS, CAS 1035968-27-4
4-[(E)-(3-Methoxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione
CAS 1035968-27-4C14H14N6OS
4-[(E)-(2,3-Dimethoxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C15H16N6O2S, CAS 714940-55-3
4-[(E)-(2,3-Dimethoxyphenyl)methylideneamino]-3-(5-methyl-1H-pyrazol-3-yl)-1H-1,2,4-triazole-5-thione
CAS 714940-55-3C15H16N6O2S
(E)-4-((2-Chloro-6-fluorobenzylidene)amino)-5-(3-methyl-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H10ClFN6S, CAS 1042675-43-3
(E)-4-((2-Chloro-6-fluorobenzylidene)amino)-5-(3-methyl-1H-pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol
CAS 1042675-43-3C13H10ClFN6S
4-{[(E)-(2,3-Dichlorophenyl)methylidene]amino}-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C13H10Cl2N6S, CAS 1037569-93-9
4-{[(E)-(2,3-Dichlorophenyl)methylidene]amino}-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol
CAS 1037569-93-9C13H10Cl2N6S
2-{[(E)-3-Mercapto-5-(5-methyl-2H-pyrazol-3-yl)-[1,2,4]triazol-4-ylimino]-methyl}-6-methoxy-phenol chemical structure, C14H14N6O2S, CAS 1189315-55-6
2-{[(E)-3-Mercapto-5-(5-methyl-2H-pyrazol-3-yl)-[1,2,4]triazol-4-ylimino]-methyl}-6-methoxy-phenol
CAS 1189315-55-6C14H14N6O2S
4-{[(E)-3-Mercapto-5-(5-methyl-2H-pyrazol-3-yl)-[1,2,4]triazol-4-ylimino]-methyl}-2-methoxy-phenol chemical structure, C14H14N6O2S, CAS 1189315-62-5
4-{[(E)-3-Mercapto-5-(5-methyl-2H-pyrazol-3-yl)-[1,2,4]triazol-4-ylimino]-methyl}-2-methoxy-phenol
CAS 1189315-62-5C14H14N6O2S
4-{[(E)-3-Mercapto-5-(5-methyl-2H-pyrazol-3-yl)-[1,2,4]triazol-4-ylimino]-methyl}-2,6-dimethoxy-phenol chemical structure, C15H16N6O3S, CAS 850241-83-7
4-{[(E)-3-Mercapto-5-(5-methyl-2H-pyrazol-3-yl)-[1,2,4]triazol-4-ylimino]-methyl}-2,6-dimethoxy-phenol
CAS 850241-83-7C15H16N6O3S