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Murcko scaffold

Ring system with 3 rings and 19 atoms

36 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
36
With full pages
8
Scaffold SMILES

S=c1[nH]nc(-c2ccco2)n1N=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(-c2ccco2)n1N=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

4-[(E)-(2-Fluorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H9FN4OS, CAS 489416-57-1
4-[(E)-(2-Fluorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 489416-57-1C13H9FN4OS
4-[(E)-(2,5-Dimethoxyphenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C15H14N4O3S, CAS 498569-09-8
4-[(E)-(2,5-Dimethoxyphenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 498569-09-8C15H14N4O3S
4-[(E)-(4-tert-Butylphenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C17H18N4OS, CAS 498571-84-9
4-[(E)-(4-tert-Butylphenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 498571-84-9C17H18N4OS
3-(Furan-2-yl)-4-[(E)-[2-(trifluoromethyl)phenyl]methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C14H9F3N4OS, CAS 488088-24-0
3-(Furan-2-yl)-4-[(E)-[2-(trifluoromethyl)phenyl]methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488088-24-0C14H9F3N4OS
3-(Furan-2-yl)-4-[(E)-(4-methylsulfanylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C14H12N4OS2, CAS 489465-32-9
3-(Furan-2-yl)-4-[(E)-(4-methylsulfanylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 489465-32-9C14H12N4OS2
4-((4-(Dimethylamino)benzylidene)amino)-5-(2-furyl)-4H-1,2,4-triazole-3-thiol chemical structure, C15H15N5OS, CAS 146173-51-5
4-((4-(Dimethylamino)benzylidene)amino)-5-(2-furyl)-4H-1,2,4-triazole-3-thiol
CAS 146173-51-5C15H15N5OS
3-(Furan-2-yl)-4-[(E)-(4-methylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C14H12N4OS, CAS 183536-26-7
3-(Furan-2-yl)-4-[(E)-(4-methylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 183536-26-7C14H12N4OS
3-(Furan-2-yl)-4-[(E)-(4-propan-2-ylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C16H16N4OS, CAS 488811-55-8
3-(Furan-2-yl)-4-[(E)-(4-propan-2-ylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488811-55-8C16H16N4OS
3-(Furan-2-yl)-4-[(E)-(3-methoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C14H12N4O2S, CAS 500278-73-9
3-(Furan-2-yl)-4-[(E)-(3-methoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 500278-73-9C14H12N4O2S
4-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H8ClFN4OS, CAS 498535-12-9
4-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 498535-12-9C13H8ClFN4OS
4-[(E)-(2-Bromophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H9BrN4OS, CAS 488842-93-9
4-[(E)-(2-Bromophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 488842-93-9C13H9BrN4OS
4-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C17H19N5OS, CAS 488793-04-0
4-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 488793-04-0C17H19N5OS
3-(Furan-2-yl)-4-[(E)-(4-methoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C14H12N4O2S, CAS 146173-52-6
3-(Furan-2-yl)-4-[(E)-(4-methoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 146173-52-6C14H12N4O2S
3-(Furan-2-yl)-4-[(E)-(3-nitrophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C13H9N5O3S, CAS 146173-50-4
3-(Furan-2-yl)-4-[(E)-(3-nitrophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 146173-50-4C13H9N5O3S
2-(2-(((3-(Furan-2-yl)-5-thioxo-1H-1,2,4-triazol-4(5H)-yl)imino)methyl)phenoxy)acetic acid chemical structure, C15H12N4O4S, CAS 478253-70-2
2-(2-(((3-(Furan-2-yl)-5-thioxo-1H-1,2,4-triazol-4(5H)-yl)imino)methyl)phenoxy)acetic acid
CAS 478253-70-2C15H12N4O4S
[4-[(E)-[3-(Furan-2-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]-2,6-dimethoxyphenyl] acetate chemical structure, C17H16N4O5S, CAS 498538-22-0
[4-[(E)-[3-(Furan-2-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]-2,6-dimethoxyphenyl] acetate
CAS 498538-22-0C17H16N4O5S
3-(Furan-2-yl)-4-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C16H16N4O4S, CAS 488796-91-4
3-(Furan-2-yl)-4-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488796-91-4C16H16N4O4S
[4-[(E)-[3-(Furan-2-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]-2-methoxyphenyl] acetate chemical structure, C16H14N4O4S, CAS 488130-54-7
[4-[(E)-[3-(Furan-2-yl)-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]-2-methoxyphenyl] acetate
CAS 488130-54-7C16H14N4O4S
3-(Furan-2-yl)-4-[(E)-(2-methylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C14H12N4OS, CAS 500143-80-6
3-(Furan-2-yl)-4-[(E)-(2-methylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 500143-80-6C14H12N4OS
4-[(E)-(5-Bromo-2-methoxyphenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C14H11BrN4O2S, CAS 489444-37-3
4-[(E)-(5-Bromo-2-methoxyphenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 489444-37-3C14H11BrN4O2S
4-[(E)-(3-Chlorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H9ClN4OS, CAS 489401-10-7
4-[(E)-(3-Chlorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 489401-10-7C13H9ClN4OS
4-[(E)-(3,4-Dichlorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H8Cl2N4OS, CAS 497943-69-8
4-[(E)-(3,4-Dichlorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 497943-69-8C13H8Cl2N4OS
3-(Furan-2-yl)-4-[(E)-[4-(trifluoromethyl)phenyl]methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C14H9F3N4OS, CAS 497076-30-9
3-(Furan-2-yl)-4-[(E)-[4-(trifluoromethyl)phenyl]methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 497076-30-9C14H9F3N4OS
4-[(E)-(5-Bromo-2-fluorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H8BrFN4OS, CAS 497075-97-5
4-[(E)-(5-Bromo-2-fluorophenyl)methylideneamino]-3-(furan-2-yl)-1H-1,2,4-triazole-5-thione
CAS 497075-97-5C13H8BrFN4OS