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Murcko scaffold

2,3,4,5-Tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepin-1-one scaffold

15 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
15
With full pages
3
Scaffold SMILES

O=C1NCCCn2cccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3,4,5-Tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepin-1-one page
Murcko scaffold O=C1NCCCn2cccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

2,3,4,5-Tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C8H10N2O, CAS 55414-89-6
2,3,4,5-Tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepin-1-one
CAS 55414-89-6C8H10N2O
Ethyl 1-oxo-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepine-8-carboxylate chemical structure, C11H14N2O3, CAS 1338563-17-9
Ethyl 1-oxo-2,3,4,5-tetrahydro-1H-pyrrolo[1,2-a][1,4]diazepine-8-carboxylate
CAS 1338563-17-9C11H14N2O3
8-Iodo-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C8H9IN2O, CAS 1416221-54-9
8-Iodo-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepin-1-one
CAS 1416221-54-9C8H9IN2O
8-Bromo-1H,2H,3H,4H,5H-pyrrolo(1,2-a)(1,4)diazepin-1-one chemical structure, C8H9BrN2O, CAS 1379343-79-9
8-Bromo-1H,2H,3H,4H,5H-pyrrolo(1,2-a)(1,4)diazepin-1-one
CAS 1379343-79-9C8H9BrN2O
1-Oxo-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepine-8-sulfonyl chloride chemical structure, C8H9ClN2O3S, CAS 1598254-88-6
1-Oxo-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepine-8-sulfonyl chloride
CAS 1598254-88-6C8H9ClN2O3S
8-Bromo-5-methyl-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C9H11BrN2O, CAS 1870471-98-9
8-Bromo-5-methyl-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepin-1-one
CAS 1870471-98-9C9H11BrN2O
8-Bromo-3-methyl-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C9H11BrN2O, CAS 1864878-16-9
8-Bromo-3-methyl-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one
CAS 1864878-16-9C9H11BrN2O
(4R)-8-Bromo-4-methoxy-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C9H11BrN2O2, CAS 2566874-78-8
(4R)-8-Bromo-4-methoxy-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one
CAS 2566874-78-8C9H11BrN2O2
8-Bromo-9-fluoro-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C8H8BrFN2O, CAS 2566874-58-4
8-Bromo-9-fluoro-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one
CAS 2566874-58-4C8H8BrFN2O
8-Bromo-9-chloro-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C8H8BrClN2O, CAS 2566874-55-1
8-Bromo-9-chloro-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one
CAS 2566874-55-1C8H8BrClN2O
8-Bromo-4,4-difluoro-3,5-dihydro-2H-pyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C8H7BrF2N2O, CAS 2566874-75-5
8-Bromo-4,4-difluoro-3,5-dihydro-2H-pyrrolo[1,2-a][1,4]diazepin-1-one
CAS 2566874-75-5C8H7BrF2N2O
8-Bromo-1-oxo-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepine-4-carboxylic acid chemical structure, C9H9BrN2O3, CAS 2566875-25-8
8-Bromo-1-oxo-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepine-4-carboxylic acid
CAS 2566875-25-8C9H9BrN2O3
8-Bromo-4-(hydroxymethyl)-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one chemical structure, C9H11BrN2O2, CAS 2566875-26-9
8-Bromo-4-(hydroxymethyl)-2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]diazepin-1-one
CAS 2566875-26-9C9H11BrN2O2
1-Oxo-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepine-8-carboxylic acid chemical structure, C9H10N2O3, CAS 2408958-68-7
1-Oxo-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepine-8-carboxylic acid
CAS 2408958-68-7C9H10N2O3
1-Oxo-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepine-8-sulfonyl fluoride chemical structure, C8H9FN2O3S, CAS 2138262-07-2
1-Oxo-1H,2H,3H,4H,5H-pyrrolo[1,2-a][1,4]diazepine-8-sulfonyl fluoride
CAS 2138262-07-2C8H9FN2O3S