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Murcko scaffold

[4-(Benzenesulfonyl)piperazin-1-yl]-cyclopropylmethanone scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
7
With full pages
3
Scaffold SMILES

O=C(C1CC1)N1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the [4-(Benzenesulfonyl)piperazin-1-yl]-cyclopropylmethanone page
Murcko scaffold O=C(C1CC1)N1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Cyclopropyl-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]methanone chemical structure, C15H20N2O4S, CAS 562869-20-9
Cyclopropyl-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]methanone
CAS 562869-20-9C15H20N2O4S
[4-(Benzenesulfonyl)piperazin-1-yl]-cyclopropylmethanone chemical structure, C14H18N2O3S, CAS 849185-43-9
[4-(Benzenesulfonyl)piperazin-1-yl]-cyclopropylmethanone
CAS 849185-43-9C14H18N2O3S
[4-(4-Ethoxyphenyl)sulfonylpiperazin-1-yl]-(2-methylcyclopropyl)methanone chemical structure, C17H24N2O4S, CAS 851209-99-9
[4-(4-Ethoxyphenyl)sulfonylpiperazin-1-yl]-(2-methylcyclopropyl)methanone
CAS 851209-99-9C17H24N2O4S
1-Cyclopropanecarbonyl-4-(2,5-dichlorobenzenesulfonyl)piperazine chemical structure, C14H16Cl2N2O3S, CAS 1002579-08-9
1-Cyclopropanecarbonyl-4-(2,5-dichlorobenzenesulfonyl)piperazine
CAS 1002579-08-9C14H16Cl2N2O3S
N-[4-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]sulfonyl]-2-methoxyphenyl]acetamide chemical structure, C17H23N3O5S, CAS 877964-69-7
N-[4-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]sulfonyl]-2-methoxyphenyl]acetamide
CAS 877964-69-7C17H23N3O5S
(4-(4-tert-Butylphenylsulfonyl)piperazin-1-yl)(cyclopropyl)methanone chemical structure, C18H26N2O3S, CAS 925580-64-9
(4-(4-tert-Butylphenylsulfonyl)piperazin-1-yl)(cyclopropyl)methanone
CAS 925580-64-9C18H26N2O3S
(2-Methylcyclopropyl)[4-[[4-(1-methylpropyl)phenyl]sulfonyl]-1-piperazinyl]methanone chemical structure, C19H28N2O3S, CAS 1217826-45-3
(2-Methylcyclopropyl)[4-[[4-(1-methylpropyl)phenyl]sulfonyl]-1-piperazinyl]methanone
CAS 1217826-45-3C19H28N2O3S