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Murcko scaffold

Ring system with 1 ring and 4 atoms

23 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
4
Chemicals
23
With full pages
2
Scaffold SMILES

C1C[SiH2]C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffold
Murcko scaffold C1C[SiH2]C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

Silacyclobutane, 1,1-dimethyl- chemical structure, C5H12Si, CAS 2295-12-7
Silacyclobutane, 1,1-dimethyl-
CAS 2295-12-7C5H12Si
1,1-Dichlorosilacyclobutane chemical structure, C3H6Cl2Si, CAS 2351-33-9
1,1-Dichlorosilacyclobutane
CAS 2351-33-9C3H6Cl2Si
1,1-Dimethoxysilacyclobutane chemical structure, C5H12O2Si, CAS 33446-84-3
1,1-Dimethoxysilacyclobutane
CAS 33446-84-3C5H12O2Si
1,1,3-Trimethyl-1-silacyclobutane chemical structure, C6H14Si, CAS 2295-13-8
1,1,3-Trimethyl-1-silacyclobutane
CAS 2295-13-8C6H14Si
Silacyclobutane, 1-chloro-1-methyl- chemical structure, C4H9ClSi, CAS 2351-34-0
Silacyclobutane, 1-chloro-1-methyl-
CAS 2351-34-0C4H9ClSi
1,1,2-Trimethyl-1-silacyclobutane chemical structure, C6H14Si, CAS 30681-90-4
1,1,2-Trimethyl-1-silacyclobutane
CAS 30681-90-4C6H14Si
1-Ethyl-1-methylsilacyclobutane chemical structure, C6H14Si, CAS 765-45-7
1-Ethyl-1-methylsilacyclobutane
CAS 765-45-7C6H14Si
1-Methyl-1-propylsiletane chemical structure, C7H16Si, CAS 63647-86-9
1-Methyl-1-propylsiletane
CAS 63647-86-9C7H16Si
1-Ethenyl-1-methylsiletane chemical structure, C6H12Si, CAS 3514-67-8
1-Ethenyl-1-methylsiletane
CAS 3514-67-8C6H12Si
Silacyclobutane, 1,1-bis(1-methylethyl)- chemical structure, C9H20Si, CAS 63647-96-1
Silacyclobutane, 1,1-bis(1-methylethyl)-
CAS 63647-96-1C9H20Si
1-Chloro-1,3-dimethylsiletane chemical structure, C5H11ClSi, CAS 53561-48-1
1-Chloro-1,3-dimethylsiletane
CAS 53561-48-1C5H11ClSi
Silacyclobutane, 1-[[1-[(1,1-dimethylethyl)thio]ethenyl]oxy]-1-methyl- chemical structure, C10H20OSSi, CAS 173343-40-3
Silacyclobutane, 1-[[1-[(1,1-dimethylethyl)thio]ethenyl]oxy]-1-methyl-
CAS 173343-40-3C10H20OSSi
1-Chloro-1-ethenylsiletane chemical structure, C5H9ClSi, CAS 74045-41-3
1-Chloro-1-ethenylsiletane
CAS 74045-41-3C5H9ClSi
1,1-Di-tert-butyl-2,2-dimethylsiletane chemical structure, C13H28Si, CAS 89200-91-9
1,1-Di-tert-butyl-2,2-dimethylsiletane
CAS 89200-91-9C13H28Si
Trifluoro-methanesulfonic acid 1-methylsilacyclobut-1-yl ester chemical structure, C5H9F3O3SSi, CAS 156849-48-8
Trifluoro-methanesulfonic acid 1-methylsilacyclobut-1-yl ester
CAS 156849-48-8C5H9F3O3SSi
1-Chlorosiletane chemical structure, C3H7ClSi, CAS 20156-49-4
1-Chlorosiletane
CAS 20156-49-4C3H7ClSi
1,11-Diethoxysilacyclobutane chemical structure, C7H16O2Si, CAS 74861-46-4
1,11-Diethoxysilacyclobutane
CAS 74861-46-4C7H16O2Si
1,1-Bis(chloromethyl)siletane chemical structure, C5H10Cl2Si, CAS 1239481-23-2
1,1-Bis(chloromethyl)siletane
CAS 1239481-23-2C5H10Cl2Si
1-(Dibromomethyl)-1-methylsiletane chemical structure, C5H10Br2Si, CAS 61499-45-4
1-(Dibromomethyl)-1-methylsiletane
CAS 61499-45-4C5H10Br2Si
3-[(1-Methylsiletan-1-yl)oxy]propanal chemical structure, C7H14O2Si, CAS 834881-03-7
3-[(1-Methylsiletan-1-yl)oxy]propanal
CAS 834881-03-7C7H14O2Si
1-Bromo-1,2-dimethylsiletane chemical structure, C5H11BrSi, CAS 58368-57-3
1-Bromo-1,2-dimethylsiletane
CAS 58368-57-3C5H11BrSi
Dimethylsilacyclobutane (1,1-D6) chemical structure, C5H12Si, CAS 76070-25-2
Dimethylsilacyclobutane (1,1-D6)
CAS 76070-25-2C5H12Si
3-(Dichloromethyl)-1,1-dimethylsiletane chemical structure, C6H12Cl2Si, CAS 14707-35-8
3-(Dichloromethyl)-1,1-dimethylsiletane
CAS 14707-35-8C6H12Cl2Si