Murcko scaffold
2-Azetidinone scaffold
485 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 5
- Chemicals
- 485
- With full pages
- 48
Scaffold SMILES
O=C1CCN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 485 chemicals
2-Azetidinone, 3,3-diethyl-
CAS 16006-10-3C7H13NO
Tabtoxin
CAS 40957-90-2C11H19N3O6
(-)-Tabtoxinine beta-lactam
CAS 65709-93-5C7H12N2O4
4-Acetoxy-2-azetidinone
CAS 28562-53-0C5H7NO3
SQ 26180
CAS 79720-08-4C6H10N2O6S
(2S,3S)-3-Amino-2-methyl-4-oxo-1-azetidinesulfonic acid
CAS 80082-65-1C4H8N2O4S
2-Azetidinone
CAS 930-21-2C3H5NO
2H-Azetidin-2-one, 2-methyl-
CAS 2679-13-2C4H7NO
2-Azetidinone, 4-(2-propenyl)-
CAS 68485-52-9C6H9NO
2-Azetidinone, 4-(2-propynyloxy)-
CAS 69894-51-5C6H7NO2
beta-Caprolactam
CAS 22937-03-7C6H11NO
(S)-Alanyl-3-(alpha-(S)-chloro-3-(S)-hydroxy-2-oxo-3-azetidinylmethyl)-(S)-alanine
CAS 54922-56-4C10H16ClN3O5
Proclavaminic acid
CAS 112240-59-2C8H14N2O4
4-Ethenylazetidin-2-one
CAS 7486-94-4C5H7NO
1-Methyl-3,3-dipropylazetidin-2-one
CAS 2027-63-6C10H19NO
1-(Hydroxymethyl)-3,3-dipropylazetidin-2-one
CAS 10242-66-7C10H19NO2
4-Ethenyl-1-methylazetidin-2-one
CAS 40156-34-1C6H9NO
1-(3-Isothiocyanatopropanoyl)-4-methylazetidin-2-one
CAS 50633-11-9C8H10N2O2S
2-(Chloromethyl)-2-methyl-4-oxoazetidine-1-carboxamide
CAS 53598-91-7C6H9ClN2O2
N-Methyl-2-oxoazetidine-1-carboxamide
CAS 205047-44-5C5H8N2O2
![[(2R)-4-Oxoazetidin-2-yl] acetate chemical structure, C5H7NO3, CAS 127054-87-9](/s/OEYMQQDJCUHKQS-RXMQYKEDSA-N.svg)
[(2R)-4-Oxoazetidin-2-yl] acetate
CAS 127054-87-9C5H7NO3
Methyl (3-(1-hydroxyethyl)-4-oxo-2-azetidinyl)acetate
CAS 103002-35-3C8H13NO4
4,4-Dimethylazetidin-2-one
CAS 4879-95-2C5H9NO
3,3-Dimethylazetidin-2-one
CAS 7486-91-1C5H9NO
- 3,3,4,4-Tetramethylazetidin-2-one13423-22-8C7H13NO
- 3,4,4-Trimethylazetidin-2-one22607-01-8C6H11NO
- 1,3-Ditert-butyl-2-methoxy-4-oxo-3-azetidinecarbonitrile55712-07-7C13H22N2O2
- (4R)-4-Methylazetidin-2-one26757-75-5C4H7NO
- (R)-1-(tert-Butyldimethylsilyl)-4-oxoazetidine-2-carboxylic acid162856-35-1C10H19NO3Si
- (S)-3-((R)-1-Hydroxy-ethyl)-azetidin-2-one156616-45-4C5H9NO2
- SQ 2850288403-16-1C3H5NO4S
- 7 suppliers4-Oxoazetidine-2-carboxylic acid98019-65-9C4H5NO3
- 3-Amino-2-methyl-4-oxo-azetidine-1-sulfonic acid92007-69-7C4H8N2O4S
- (2R,3S)-3-((R)-1-((tert-Butyldimethylsilyl)oxy)ethyl)-4-oxoazetidin-2-yl acetate80951-41-3C13H25NO4Si
- 2-Azetidinone, 1-chloro-153357-31-4C3H4ClNO
- 4-Methylazetidin-2-one5303-64-0C4H7NO
- 7 suppliers(R)-2-[(3S,4S)-3-[(R)-1-(tert-Butyldimethylsilyloxy)ethyl]-2-oxoazetidin-4-yl]propionic acid90776-58-2C14H27NO4Si
- Sulfazecin77912-79-9C12H20N4O9S
- (2S,3R)-1-(tert-Butyldimethylsilyl)-3-methyl-4-oxoazetidine-2-carboxylic acid95730-34-0C11H21NO3Si
- 4-Methyl-4-propylazetidin-2-one13049-20-2C7H13NO
- (R)-Methyl 2-(3-amino-2-oxoazetidin-1-yl)acetate737731-48-5C6H10N2O3
- 1 suppliers(2R)-4-Oxoazetidine-2-carboxylic acid62860-12-2C4H5NO3
- 3,3-Diethyl-4-oxoazetidin-2-yl propionate142935-44-2C10H17NO3
- (3S)-4-(Acetyloxy)-3-butyl-3-ethyl-2-azetidinone1026715-04-7C11H19NO3
- tert-Butyl (2S,3R)-3-(1-ethoxyethoxy)-2-(2-methylpropyl)-4-oxoazetidine-1-carboxylate201856-62-4C16H29NO5
- 2-Azetidinone, 4-(acetyloxy)-3,3-diethyl-126997-07-7C9H15NO3
- (3S,4S)-4-Ethynyl-3-methoxyazetidin-2-one158612-61-4C6H7NO2
- (3R)-3-Propan-2-yl-3-propylazetidin-2-one154520-37-3C9H17NO
Related scaffolds
Same ring framework with different atoms or bond orders
