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Murcko scaffold

6,7-Dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one scaffold

28 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
28
With full pages
3
Scaffold SMILES

O=c1[nH]cnc2c1CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6,7-Dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one page
Murcko scaffold O=c1[nH]cnc2c1CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

2,3-Diamino-3H,4H,5H,6H,7H-cyclopenta[d]pyrimidin-4-one chemical structure, C7H10N4O, CAS 95095-59-3
2,3-Diamino-3H,4H,5H,6H,7H-cyclopenta[d]pyrimidin-4-one
CAS 95095-59-3C7H10N4O
2-(4-Oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-3-yl)acetic acid chemical structure, C9H10N2O3, CAS 1215948-45-0
2-(4-Oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-3-yl)acetic acid
CAS 1215948-45-0C9H10N2O3
4H-Cyclopentapyrimidin-4-one, 3,5,6,7-tetrahydro-3-(2-propynyl)- chemical structure, C10H10N2O, CAS 774-08-3
4H-Cyclopentapyrimidin-4-one, 3,5,6,7-tetrahydro-3-(2-propynyl)-
CAS 774-08-3C10H10N2O
6,7-Dihydro-2-(methylthio)-5H-cyclopenta[d]pyrimidin-4-ol chemical structure, C8H10N2OS, CAS 3087-14-7
6,7-Dihydro-2-(methylthio)-5H-cyclopenta[d]pyrimidin-4-ol
CAS 3087-14-7C8H10N2OS
2-Amino-5H,6H,7H-cyclopenta[d]pyrimidin-4-ol chemical structure, C7H9N3O, CAS 33081-06-0
2-Amino-5H,6H,7H-cyclopenta[d]pyrimidin-4-ol
CAS 33081-06-0C7H9N3O
6,7-Dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one chemical structure, C7H8N2O, CAS 5661-01-8
6,7-Dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
CAS 5661-01-8C7H8N2O
2-tert-Butyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-ol chemical structure, C11H16N2O, CAS 145475-37-2
2-tert-Butyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-ol
CAS 145475-37-2C11H16N2O
2-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ol chemical structure, C8H10N2O, CAS 65818-01-1
2-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ol
CAS 65818-01-1C8H10N2O
2-(Chloromethyl)-6,7-dihydro-3H-cyclopenta[D]pyrimidin-4(5H)-one chemical structure, C8H9ClN2O, CAS 1518133-04-4
2-(Chloromethyl)-6,7-dihydro-3H-cyclopenta[D]pyrimidin-4(5H)-one
CAS 1518133-04-4C8H9ClN2O
2-Amino-6-methyl-6,7-dihydro-3H-cyclopenta[D]pyrimidin-4(5H)-one chemical structure, C8H11N3O, CAS 1204408-19-4
2-Amino-6-methyl-6,7-dihydro-3H-cyclopenta[D]pyrimidin-4(5H)-one
CAS 1204408-19-4C8H11N3O
6-Methyl-6,7-dihydro-3H-cyclopenta[D]pyrimidin-4(5H)-one chemical structure, C8H10N2O, CAS 1823349-06-9
6-Methyl-6,7-dihydro-3H-cyclopenta[D]pyrimidin-4(5H)-one
CAS 1823349-06-9C8H10N2O
2-(Propylsulfanyl)-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one chemical structure, C10H14N2OS, CAS 448930-10-7
2-(Propylsulfanyl)-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one
CAS 448930-10-7C10H14N2OS
2-(Allylthio)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one chemical structure, C10H12N2OS, CAS 905084-13-1
2-(Allylthio)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
CAS 905084-13-1C10H12N2OS
2-((4-Oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)acetic acid chemical structure, C9H10N2O3S, CAS 1082474-35-8
2-((4-Oxo-4,5,6,7-tetrahydro-3H-cyclopenta[d]pyrimidin-2-yl)thio)acetic acid
CAS 1082474-35-8C9H10N2O3S
2-Hydrazinyl-3H,4H,5H,6H,7H-cyclopenta(d)pyrimidin-4-one chemical structure, C7H10N4O, CAS 118633-68-4
2-Hydrazinyl-3H,4H,5H,6H,7H-cyclopenta(d)pyrimidin-4-one
CAS 118633-68-4C7H10N4O
(R)-5-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ol chemical structure, C8H10N2O, CAS 1001178-87-5
(R)-5-Methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ol
CAS 1001178-87-5C8H10N2O
2-(Aminomethyl)-6,7-dihydro-5H-cyclopenta[D]pyrimidin-4-ol chemical structure, C8H11N3O, CAS 1083368-97-1
2-(Aminomethyl)-6,7-dihydro-5H-cyclopenta[D]pyrimidin-4-ol
CAS 1083368-97-1C8H11N3O
2-(Methylamino)-3H,4H,5H,6H,7H-cyclopenta[D]pyrimidin-4-one chemical structure, C8H11N3O, CAS 1249631-12-6
2-(Methylamino)-3H,4H,5H,6H,7H-cyclopenta[D]pyrimidin-4-one
CAS 1249631-12-6C8H11N3O
6-Methyl-2-(methylthio)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one chemical structure, C9H12N2OS, CAS 1256955-59-5
6-Methyl-2-(methylthio)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
CAS 1256955-59-5C9H12N2OS
Methyl 2-amino-4-hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine-5-carboxylate chemical structure, C9H11N3O3, CAS 1426072-26-5
Methyl 2-amino-4-hydroxy-6,7-dihydro-5H-cyclopenta[d]pyrimidine-5-carboxylate
CAS 1426072-26-5C9H11N3O3
2-Chloro-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one chemical structure, C7H7ClN2O, CAS 178308-48-0
2-Chloro-3,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one
CAS 178308-48-0C7H7ClN2O
2-Bromo-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ol chemical structure, C7H7BrN2O, CAS 1780977-89-0
2-Bromo-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-ol
CAS 1780977-89-0C7H7BrN2O
7,7-Difluoro-2-(methylthio)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one chemical structure, C8H8F2N2OS, CAS 1644414-74-3
7,7-Difluoro-2-(methylthio)-6,7-dihydro-3H-cyclopenta[d]pyrimidin-4(5H)-one
CAS 1644414-74-3C8H8F2N2OS
2-(Trichloromethyl)-3H,4H,5H,6H,7H-cyclopenta[d]pyrimidin-4-one chemical structure, C8H7Cl3N2O, CAS 2137716-96-0
2-(Trichloromethyl)-3H,4H,5H,6H,7H-cyclopenta[d]pyrimidin-4-one
CAS 2137716-96-0C8H7Cl3N2O