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Murcko scaffold

Ring system with 2 rings and 9 atoms

90 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
90
With full pages
5
Scaffold SMILES

c1nc(C2CCC2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(C2CCC2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 90 chemicals

4-Cyclobutyl-1,3-thiazol-2-amine chemical structure, C7H10N2S, CAS 475058-07-2
4-Cyclobutyl-1,3-thiazol-2-amine
CAS 475058-07-2C7H10N2S
2-Bromo-4-cyclobutylthiazole chemical structure, C7H8BrNS, CAS 1159820-59-3
2-Bromo-4-cyclobutylthiazole
CAS 1159820-59-3C7H8BrNS
4-Cyclobutylthiazole-2-carboxylic acid ethyl ester chemical structure, C10H13NO2S, CAS 184154-37-8
4-Cyclobutylthiazole-2-carboxylic acid ethyl ester
CAS 184154-37-8C10H13NO2S
1-(2-Methyl-1,3-thiazol-4-yl)cyclobutan-1-amine chemical structure, C8H12N2S, CAS 760945-70-8
1-(2-Methyl-1,3-thiazol-4-yl)cyclobutan-1-amine
CAS 760945-70-8C8H12N2S
5-Bromo-4-(cyclobutyl)thiazole chemical structure, C7H8BrNS, CAS 1243839-28-2
5-Bromo-4-(cyclobutyl)thiazole
CAS 1243839-28-2C7H8BrNS
2,5-Dibromo-4-cyclobutyl-1,3-thiazole chemical structure, C7H7Br2NS, CAS 1314354-06-7
2,5-Dibromo-4-cyclobutyl-1,3-thiazole
CAS 1314354-06-7C7H7Br2NS
5-Amino-4-(cyclobutyl)thiazole chemical structure, C7H10N2S, CAS 1374664-29-5
5-Amino-4-(cyclobutyl)thiazole
CAS 1374664-29-5C7H10N2S
1-(1,3-Thiazol-4-yl)cyclobutane-1-carboxylic acid chemical structure, C8H9NO2S, CAS 1493408-29-9
1-(1,3-Thiazol-4-yl)cyclobutane-1-carboxylic acid
CAS 1493408-29-9C8H9NO2S
1-[1-(1,3-Thiazol-4-yl)cyclobutyl]methanamine chemical structure, C8H12N2S, CAS 1485403-35-7
1-[1-(1,3-Thiazol-4-yl)cyclobutyl]methanamine
CAS 1485403-35-7C8H12N2S
1-(1,3-Thiazol-4-yl)cyclobutan-1-amine chemical structure, C7H10N2S, CAS 1518491-02-5
1-(1,3-Thiazol-4-yl)cyclobutan-1-amine
CAS 1518491-02-5C7H10N2S
1-[1-(2-Methyl-1,3-thiazol-4-yl)cyclobutyl]methanamine chemical structure, C9H14N2S, CAS 1511991-40-4
1-[1-(2-Methyl-1,3-thiazol-4-yl)cyclobutyl]methanamine
CAS 1511991-40-4C9H14N2S
1-(2-Methyl-1,3-thiazol-4-yl)cyclobutane-1-carboxylic acid chemical structure, C9H11NO2S, CAS 1501099-53-1
1-(2-Methyl-1,3-thiazol-4-yl)cyclobutane-1-carboxylic acid
CAS 1501099-53-1C9H11NO2S
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutan-1-amine chemical structure, C10H16N2S, CAS 1534474-96-8
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutan-1-amine
CAS 1534474-96-8C10H16N2S
1-{1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutyl}methanamine chemical structure, C11H18N2S, CAS 1511777-15-3
1-{1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutyl}methanamine
CAS 1511777-15-3C11H18N2S
4-Cyclobutylthiazole-2-carbonyl chloride chemical structure, C8H8ClNOS, CAS 1180496-34-7
4-Cyclobutylthiazole-2-carbonyl chloride
CAS 1180496-34-7C8H8ClNOS
4-Cyclobutyl-2-thiazolecarboxylic acid chemical structure, C8H9NO2S, CAS 1180673-54-4
4-Cyclobutyl-2-thiazolecarboxylic acid
CAS 1180673-54-4C8H9NO2S
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutane-1-carboxylic acid chemical structure, C11H15NO2S, CAS 1484789-56-1
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutane-1-carboxylic acid
CAS 1484789-56-1C11H15NO2S
4-Cyclobutyl-5-methyl-1,3-thiazol-2-amine chemical structure, C8H12N2S, CAS 1698908-50-7
4-Cyclobutyl-5-methyl-1,3-thiazol-2-amine
CAS 1698908-50-7C8H12N2S
4-(1-Aminocyclobutyl)-1,3-thiazol-2-amine chemical structure, C7H11N3S, CAS 1603531-78-7
4-(1-Aminocyclobutyl)-1,3-thiazol-2-amine
CAS 1603531-78-7C7H11N3S
1-[2-(Methoxymethyl)-1,3-thiazol-4-yl]cyclobutan-1-amine chemical structure, C9H14N2OS, CAS 1597626-99-7
1-[2-(Methoxymethyl)-1,3-thiazol-4-yl]cyclobutan-1-amine
CAS 1597626-99-7C9H14N2OS
1-{1-[2-(Methoxymethyl)-1,3-thiazol-4-yl]cyclobutyl}methanamine chemical structure, C10H16N2OS, CAS 1599903-72-6
1-{1-[2-(Methoxymethyl)-1,3-thiazol-4-yl]cyclobutyl}methanamine
CAS 1599903-72-6C10H16N2OS
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutane-1-carbonitrile chemical structure, C11H14N2S, CAS 1889568-22-2
1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutane-1-carbonitrile
CAS 1889568-22-2C11H14N2S
1-(2-Methyl-1,3-thiazol-4-yl)cyclobutane-1-carbonitrile chemical structure, C9H10N2S, CAS 1889540-53-7
1-(2-Methyl-1,3-thiazol-4-yl)cyclobutane-1-carbonitrile
CAS 1889540-53-7C9H10N2S
{1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutyl}methanol chemical structure, C11H17NOS, CAS 1891352-38-7
{1-[2-(Propan-2-yl)-1,3-thiazol-4-yl]cyclobutyl}methanol
CAS 1891352-38-7C11H17NOS