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Murcko scaffold

Ring system with 3 rings and 23 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
6
With full pages
4
Scaffold SMILES

O=C(COC(=O)c1ccc2ccccc2c1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1ccc2ccccc2c1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

[2-(4-Carbamoylanilino)-2-oxoethyl] 3-hydroxynaphthalene-2-carboxylate chemical structure, C20H16N2O5, CAS 744205-61-6
[2-(4-Carbamoylanilino)-2-oxoethyl] 3-hydroxynaphthalene-2-carboxylate
CAS 744205-61-6C20H16N2O5
[2-(2-Fluoroanilino)-2-oxoethyl] 3-hydroxynaphthalene-2-carboxylate chemical structure, C19H14FNO4, CAS 744233-88-3
[2-(2-Fluoroanilino)-2-oxoethyl] 3-hydroxynaphthalene-2-carboxylate
CAS 744233-88-3C19H14FNO4
[2-(N-Methylanilino)-2-oxoethyl] 3-hydroxynaphthalene-2-carboxylate chemical structure, C20H17NO4, CAS 387854-56-0
[2-(N-Methylanilino)-2-oxoethyl] 3-hydroxynaphthalene-2-carboxylate
CAS 387854-56-0C20H17NO4
[2-[2-Chloro-5-(trifluoromethyl)anilino]-2-oxoethyl] 1,4-dihydroxynaphthalene-2-carboxylate chemical structure, C20H13ClF3NO5, CAS 5388-80-7
[2-[2-Chloro-5-(trifluoromethyl)anilino]-2-oxoethyl] 1,4-dihydroxynaphthalene-2-carboxylate
CAS 5388-80-7C20H13ClF3NO5
[(Cyanomethyl)(phenyl)carbamoyl]methyl 1,4-dihydroxynaphthalene-2-carboxylate chemical structure, C21H16N2O5, CAS 949679-02-1
[(Cyanomethyl)(phenyl)carbamoyl]methyl 1,4-dihydroxynaphthalene-2-carboxylate
CAS 949679-02-1C21H16N2O5
[1-(4-Carbamoylanilino)-1-oxopropan-2-yl] 1,4-dihydroxynaphthalene-2-carboxylate chemical structure, C21H18N2O6, CAS 1090845-24-1
[1-(4-Carbamoylanilino)-1-oxopropan-2-yl] 1,4-dihydroxynaphthalene-2-carboxylate
CAS 1090845-24-1C21H18N2O6