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Murcko scaffold

Ring system with 3 rings and 17 atoms

42 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
42
With full pages
13
Scaffold SMILES

c1csc(COc2cccc3ccccc23)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(COc2cccc3ccccc23)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

Duloxetine hydrochloride chemical structure, C18H20ClNOS, CAS 136434-34-9
Duloxetine hydrochloride
CAS 136434-34-9C18H20ClNOS
Duloxetine chemical structure, C18H19NOS, CAS 116539-59-4
Duloxetine
CAS 116539-59-4C18H19NOS
(±)-Duloxetine chemical structure, C18H19NOS, CAS 116817-13-1
(±)-Duloxetine
CAS 116817-13-1C18H19NOS
(S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine chemical structure, C19H21NOS, CAS 132335-46-7
(S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
CAS 132335-46-7C19H21NOS
(S)-2-(3-Chloro-1-(naphthalen-1-yloxy)propyl)thiophene chemical structure, C17H15ClOS, CAS 164071-61-8
(S)-2-(3-Chloro-1-(naphthalen-1-yloxy)propyl)thiophene
CAS 164071-61-8C17H15ClOS
5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naphthalen-2-ol chemical structure, C18H19NO2S, CAS 741693-76-5
5-((S)-3-Methylamino-1-thiophen-2-yl-propoxy)-naphthalen-2-ol
CAS 741693-76-5C18H19NO2S
(S)-Norduloxetine chemical structure, C17H17NOS, CAS 178273-35-3
(S)-Norduloxetine
CAS 178273-35-3C17H17NOS
(R)-Duloxetine chemical structure, C18H19NOS, CAS 116539-60-7
(R)-Duloxetine
CAS 116539-60-7C18H19NOS
N,N-Dimethyl-3-((naphthalen-1-yl)oxy)-3-(thiophen-2-yl)propan-1-amine chemical structure, C19H21NOS, CAS 2241983-09-3
N,N-Dimethyl-3-((naphthalen-1-yl)oxy)-3-(thiophen-2-yl)propan-1-amine
CAS 2241983-09-3C19H21NOS
(S)-(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine oxalate chemical structure, C20H21NO5S, CAS 116817-77-7
(S)-(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine oxalate
CAS 116817-77-7C20H21NO5S
(3S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate chemical structure, C21H23NO5S, CAS 132335-47-8
(3S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine ethanedioate
CAS 132335-47-8C21H23NO5S
LY 227942 chemical structure, C20H21NO5S, CAS 116817-14-2
LY 227942
CAS 116817-14-2C20H21NO5S
Duloxetine maleate chemical structure, C22H23NO5S, CAS 116817-86-8
Duloxetine maleate
CAS 116817-86-8C22H23NO5S
Duloxetine hydrochloride, (R)- chemical structure, C18H20ClNOS, CAS 910138-96-4
Duloxetine hydrochloride, (R)-
CAS 910138-96-4C18H20ClNOS
(R)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine chemical structure, C19H21NOS, CAS 878757-08-5
(R)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine
CAS 878757-08-5C19H21NOS
4-((1S)-3-(Methylamino)-1-(2-thienyl)propoxy)-1-naphthalenol chemical structure, C18H19NO2S, CAS 662149-13-5
4-((1S)-3-(Methylamino)-1-(2-thienyl)propoxy)-1-naphthalenol
CAS 662149-13-5C18H19NO2S
5-Hydroxy-6-methoxy duloxetine chemical structure, C19H21NO3S, CAS 741693-79-8
5-Hydroxy-6-methoxy duloxetine
CAS 741693-79-8C19H21NO3S
(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine phosphate chemical structure, C19H24NO5PS, CAS 161005-84-1
(S)-N,N-Dimethyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine phosphate
CAS 161005-84-1C19H24NO5PS
(RS)-Duloxetine hydrochloride chemical structure, C18H20ClNOS, CAS 116817-11-9
(RS)-Duloxetine hydrochloride
CAS 116817-11-9C18H20ClNOS
Sodium 2-methoxy-5-[(1S)-3-(methylamino)-1-(thiophen-2-yl)propoxy]naphthalen-1-yl sulfate chemical structure, C19H20NNaO6S2, CAS 662149-10-2
Sodium 2-methoxy-5-[(1S)-3-(methylamino)-1-(thiophen-2-yl)propoxy]naphthalen-1-yl sulfate
CAS 662149-10-2C19H20NNaO6S2
5-Hydroxy-6-methoxy Duloxetine Sulfate chemical structure, C19H21NO6S2, CAS 732983-57-2
5-Hydroxy-6-methoxy Duloxetine Sulfate
CAS 732983-57-2C19H21NO6S2
5-[(1S)-3-(Methylamino)-1-(thiophen-2-yl)propoxy]naphthalene-1,2-diol chemical structure, C18H19NO3S, CAS 741693-78-7
5-[(1S)-3-(Methylamino)-1-(thiophen-2-yl)propoxy]naphthalene-1,2-diol
CAS 741693-78-7C18H19NO3S
5-Hydroxyduloxetine chemical structure, C18H19NO2S, CAS 741693-77-6
5-Hydroxyduloxetine
CAS 741693-77-6C18H19NO2S
Duloxetine-d7 chemical structure, C18H19NOS, CAS 919514-01-5
Duloxetine-d7
CAS 919514-01-5C18H19NOS