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Murcko scaffold

Ring system with 3 rings and 17 atoms

18 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 17
Chemicals: 18
With full pages: 6

Scaffold SMILES

c1cnc2c(OCc3nnc[nH]3)cccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1cnc2c(OCc3nnc[nH]3)cccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

2-((4-Ethyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C16H17N5O2S, CAS 496776-55-7

2-((4-Ethyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide

CAS 496776-55-7C₁₆H₁₇N₅O₂S

2-[[4-Methyl-5-(quinolin-8-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]acetic acid chemical structure, C15H14N4O3S, CAS 612525-77-6

2-[[4-Methyl-5-(quinolin-8-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]acetic acid

CAS 612525-77-6C₁₅H₁₄N₄O₃S

2-((4-Methyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide chemical structure, C15H15N5O2S, CAS 612525-79-8

2-((4-Methyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide

CAS 612525-79-8C₁₅H₁₅N₅O₂S

2-[4-Ethyl-5-(8-quinolyloxymethyl)-1,2,4-triazol-3-ylthio]acetic acid chemical structure, C16H16N4O3S, CAS 496776-38-6

2-[4-Ethyl-5-(8-quinolyloxymethyl)-1,2,4-triazol-3-ylthio]acetic acid

CAS 496776-38-6C₁₆H₁₆N₄O₃S

2-[[4-Methyl-5-[(2-methylquinolin-8-yl)oxymethyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C16H17N5O2S, CAS 637325-75-8

2-[[4-Methyl-5-[(2-methylquinolin-8-yl)oxymethyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 637325-75-8C₁₆H₁₇N₅O₂S

2-Methyl-8-[(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)methoxy]quinoline chemical structure, C15H16N4OS, CAS 637325-78-1

2-Methyl-8-[(4-methyl-5-methylsulfanyl-1,2,4-triazol-3-yl)methoxy]quinoline

CAS 637325-78-1C₁₅H₁₆N₄OS

2-Methyl-8-[(5-methylsulfanyl-4-prop-2-enyl-1,2,4-triazol-3-yl)methoxy]quinoline chemical structure, C17H18N4OS, CAS 638136-08-0

2-Methyl-8-[(5-methylsulfanyl-4-prop-2-enyl-1,2,4-triazol-3-yl)methoxy]quinoline

CAS 638136-08-0C₁₇H₁₈N₄OS

Methyl ({4-allyl-5-[(8-quinolinyloxy)methyl]-4H-1,2,4-triazol-3-yl}thio)acetate chemical structure, C18H18N4O3S, CAS 496776-08-0

Methyl ({4-allyl-5-[(8-quinolinyloxy)methyl]-4H-1,2,4-triazol-3-yl}thio)acetate

CAS 496776-08-0C₁₈H₁₈N₄O₃S

Methyl 2-((4-ethyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetate chemical structure, C17H18N4O3S, CAS 496776-18-2

Methyl 2-((4-ethyl-5-((quinolin-8-yloxy)methyl)-4H-1,2,4-triazol-3-yl)thio)acetate

CAS 496776-18-2C₁₇H₁₈N₄O₃S

2-[[5-[(5-Chloroquinolin-8-yl)oxymethyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C17H16ClN5O2S, CAS 690246-52-7

2-[[5-[(5-Chloroquinolin-8-yl)oxymethyl]-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]acetamide

CAS 690246-52-7C₁₇H₁₆ClN₅O₂S

({4-Allyl-5-[(8-quinolinyloxy)methyl]-4H-1,2,4-triazol-3-yl}thio)acetic acid chemical structure, C17H16N4O3S, CAS 102061-72-3

({4-Allyl-5-[(8-quinolinyloxy)methyl]-4H-1,2,4-triazol-3-yl}thio)acetic acid

CAS 102061-72-3C₁₇H₁₆N₄O₃S

3-[4-Prop-2-enyl-5-(8-quinolyloxymethyl)-1,2,4-triazol-3-ylthio]propanoic acid chemical structure, C18H18N4O3S, CAS 690249-75-3

3-[4-Prop-2-enyl-5-(8-quinolyloxymethyl)-1,2,4-triazol-3-ylthio]propanoic acid

CAS 690249-75-3C₁₈H₁₈N₄O₃S

2-[(5-{[(5-Chloroquinolin-8-yl)oxy]methyl}-4-ethyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C16H16ClN5O2S, CAS 1002008-36-7

2-[(5-{[(5-Chloroquinolin-8-yl)oxy]methyl}-4-ethyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide

CAS 1002008-36-7C₁₆H₁₆ClN₅O₂S

5-Chloro-8-[[5-(difluoromethylsulfanyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]methoxy]quinoline chemical structure, C16H13ClF2N4OS, CAS 690246-57-2

5-Chloro-8-[[5-(difluoromethylsulfanyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]methoxy]quinoline

CAS 690246-57-2C₁₆H₁₃ClF₂N₄OS

2-[4-Prop-2-enyl-5-(8-quinolyloxymethyl)-1,2,4-triazol-3-ylthio]ethanenitrile chemical structure, C17H15N5OS, CAS 690249-88-8

2-[4-Prop-2-enyl-5-(8-quinolyloxymethyl)-1,2,4-triazol-3-ylthio]ethanenitrile

CAS 690249-88-8C₁₇H₁₅N₅OS

8-((5-((Difluoromethyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)methoxy)quinoline chemical structure, C15H14F2N4OS, CAS 638135-88-3

8-((5-((Difluoromethyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)methoxy)quinoline

CAS 638135-88-3C₁₅H₁₄F₂N₄OS

2-[(5-{[(5-Chloroquinolin-8-yl)oxy]methyl}-4-ethyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide, pentakis(benzonitrile) chemical structure, C87H85Cl5N26O10S5, CAS 1171583-20-2

2-[(5-{[(5-Chloroquinolin-8-yl)oxy]methyl}-4-ethyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetamide, pentakis(benzonitrile)

CAS 1171583-20-2C₈₇H₈₅Cl₅N₂₆O₁₀S₅

Benzonitrile, 2-[[5-[(5-chloroquinolin-8-yl)oxymethyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C51H41ClN10O2S

Benzonitrile, 2-[[5-[(5-chloroquinolin-8-yl)oxymethyl]-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamide

C₅₁H₄₁ClN₁₀O₂S