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Murcko scaffold

N-Phenyl-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide scaffold

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
6
With full pages
1
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc2c(c1)OCCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)c1ccc2c(c1)OCCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N-Phenyl-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide chemical structure, C16H15NO3, CAS 712271-19-7
N-Phenyl-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide
CAS 712271-19-7C16H15NO3
Ethyl 4-[(3,4-dihydro-2H-1,5-benzodioxepin-7-ylcarbonyl)amino]benzoate chemical structure, C19H19NO5, CAS 874464-72-9
Ethyl 4-[(3,4-dihydro-2H-1,5-benzodioxepin-7-ylcarbonyl)amino]benzoate
CAS 874464-72-9C19H19NO5
Methyl 2-(2H,3H,4H-benzo[b]1,4-dioxepin-7-ylcarbonylamino)-4-chlorobenzoate chemical structure, C18H16ClNO5, CAS 853891-22-2
Methyl 2-(2H,3H,4H-benzo[b]1,4-dioxepin-7-ylcarbonylamino)-4-chlorobenzoate
CAS 853891-22-2C18H16ClNO5
N-(4-Fluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide chemical structure, C16H14FNO3, CAS 853891-24-4
N-(4-Fluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide
CAS 853891-24-4C16H14FNO3
N-(4-Methylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide chemical structure, C17H17NO3, CAS 853891-27-7
N-(4-Methylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide
CAS 853891-27-7C17H17NO3
8-Methyl-N-[3-(trifluoromethyl)phenyl]-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide chemical structure, C18H16F3NO3, CAS 1147199-73-2
8-Methyl-N-[3-(trifluoromethyl)phenyl]-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxamide
CAS 1147199-73-2C18H16F3NO3