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Murcko scaffold

Ring system with 3 rings and 21 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
23
With full pages
3
Scaffold SMILES

O=S(=O)(Nc1ccccc1)c1ccc2c(c1)OCCCO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccccc1)c1ccc2c(c1)OCCCO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-(4-Aminophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C15H16N2O4S, CAS 790271-22-6
N-(4-Aminophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 790271-22-6C15H16N2O4S
3-[(3,4-Dihydro-2H-1,5-benzodioxepin-7-ylsulfonyl)amino]benzoic acid chemical structure, C16H15NO6S, CAS 790272-30-9
3-[(3,4-Dihydro-2H-1,5-benzodioxepin-7-ylsulfonyl)amino]benzoic acid
CAS 790272-30-9C16H15NO6S
4-(3,4-Dihydro-2H-1,5-benzodioxepine-7-sulfonamido)benzoic acid chemical structure, C16H15NO6S, CAS 790272-44-5
4-(3,4-Dihydro-2H-1,5-benzodioxepine-7-sulfonamido)benzoic acid
CAS 790272-44-5C16H15NO6S
N-(4-Fluoro-3-nitrophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C15H13FN2O6S, CAS 790681-73-1
N-(4-Fluoro-3-nitrophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 790681-73-1C15H13FN2O6S
N-(2,5-Dimethylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C17H19NO4S, CAS 941053-21-0
N-(2,5-Dimethylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941053-21-0C17H19NO4S
N-(4-Bromophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C15H14BrNO4S, CAS 941971-04-6
N-(4-Bromophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941971-04-6C15H14BrNO4S
N-(3-Bromophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C15H14BrNO4S, CAS 941881-10-3
N-(3-Bromophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941881-10-3C15H14BrNO4S
N-(3-Methoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C16H17NO5S, CAS 942006-98-6
N-(3-Methoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 942006-98-6C16H17NO5S
N-(2,4-Dimethylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C17H19NO4S, CAS 942007-01-4
N-(2,4-Dimethylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 942007-01-4C17H19NO4S
N-(2,4,6-Trimethylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C18H21NO4S, CAS 1007797-89-8
N-(2,4,6-Trimethylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 1007797-89-8C18H21NO4S
N-[3-(3,4-Dihydro-2H-1,5-benzodioxepine-7-sulfonamido)phenyl]acetamide chemical structure, C17H18N2O5S, CAS 941928-44-5
N-[3-(3,4-Dihydro-2H-1,5-benzodioxepine-7-sulfonamido)phenyl]acetamide
CAS 941928-44-5C17H18N2O5S
N-(3,5-Dimethylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C17H19NO4S, CAS 941928-41-2
N-(3,5-Dimethylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941928-41-2C17H19NO4S
N-(3-Fluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C15H14FNO4S, CAS 942006-95-3
N-(3-Fluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 942006-95-3C15H14FNO4S
N-(5-Chloro-2-methoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C16H16ClNO5S, CAS 942007-04-7
N-(5-Chloro-2-methoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 942007-04-7C16H16ClNO5S
N-(2-Fluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C15H14FNO4S, CAS 941971-02-4
N-(2-Fluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941971-02-4C15H14FNO4S
N-(2,4-Difluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C15H13F2NO4S, CAS 941971-06-8
N-(2,4-Difluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941971-06-8C15H13F2NO4S
N-(3-Chloro-4-fluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C15H13ClFNO4S, CAS 941928-39-8
N-(3-Chloro-4-fluorophenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941928-39-8C15H13ClFNO4S
N-Methyl-N-phenyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine-7-sulfonamide chemical structure, C16H17NO4S, CAS 942006-92-0
N-Methyl-N-phenyl-3,4-dihydro-2H-benzo[b][1,4]dioxepine-7-sulfonamide
CAS 942006-92-0C16H17NO4S
N-(3-Methylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C16H17NO4S, CAS 941881-08-9
N-(3-Methylphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941881-08-9C16H17NO4S
N-(p-Tolyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepine-7-sulfonamide chemical structure, C16H17NO4S, CAS 941928-35-4
N-(p-Tolyl)-3,4-dihydro-2H-benzo[b][1,4]dioxepine-7-sulfonamide
CAS 941928-35-4C16H17NO4S
N-(2-Methoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C16H17NO5S, CAS 941928-37-6
N-(2-Methoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941928-37-6C16H17NO5S
N-(2-Ethoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C17H19NO5S, CAS 941881-12-5
N-(2-Ethoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941881-12-5C17H19NO5S
N-(2,5-Dimethoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide chemical structure, C17H19NO6S, CAS 941971-09-1
N-(2,5-Dimethoxyphenyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide
CAS 941971-09-1C17H19NO6S