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Murcko scaffold

Ring system with 2 rings and 17 atoms

10 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
10
With full pages
6
Scaffold SMILES

O=C1CC(CCC2CCCCC2=O)CC(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC(CCC2CCCCC2=O)CC(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

4-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-2,6-piperidinedione chemical structure, C15H23NO4, CAS 17280-60-3
4-(2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-2,6-piperidinedione
CAS 17280-60-3C15H23NO4
Cycloheximide chemical structure, C15H23NO4, CAS 66-81-9
Cycloheximide
CAS 66-81-9C15H23NO4
4-((2R)-2-((1S,3S,5R)-5-(Acetyloxy)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-2,6-piperidinedione chemical structure, C17H25NO6, CAS 2885-39-4
4-((2R)-2-((1S,3S,5R)-5-(Acetyloxy)-3,5-dimethyl-2-oxocyclohexyl)-2-hydroxyethyl)-2,6-piperidinedione
CAS 2885-39-4C17H25NO6
Streptovitacin A chemical structure, C15H23NO5, CAS 523-86-4
Streptovitacin A
CAS 523-86-4C15H23NO5
Naramycin B chemical structure, C15H23NO4, CAS 642-81-9
Naramycin B
CAS 642-81-9C15H23NO4
1-(3,5-Dimethyl-2-oxocyclohexyl)-2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-4-yl)ethyl hexadecanoate chemical structure, C31H53NO5, CAS 1674-74-4
1-(3,5-Dimethyl-2-oxocyclohexyl)-2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-4-yl)ethyl hexadecanoate
CAS 1674-74-4C31H53NO5
E 73 acetate chemical structure, C19H27NO7, CAS 4348-92-9
E 73 acetate
CAS 4348-92-9C19H27NO7
Isocycloheximide chemical structure, C15H23NO4, CAS 6746-42-5
Isocycloheximide
CAS 6746-42-5C15H23NO4
Cycloheximide acetate chemical structure, C17H25NO5, CAS 1508-62-9
Cycloheximide acetate
CAS 1508-62-9C17H25NO5
4-[2-Hydroxy-2-(4-hydroxy-3,5-dimethyl-2-oxocyclohexyl)ethyl]piperidine-2,6-dione chemical structure, C15H23NO5, CAS 634-50-4
4-[2-Hydroxy-2-(4-hydroxy-3,5-dimethyl-2-oxocyclohexyl)ethyl]piperidine-2,6-dione
CAS 634-50-4C15H23NO5