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Murcko scaffold

Ring system with 4 rings and 20 atoms

4 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
4
With full pages
0
Scaffold SMILES

O=c1c(=Cc2ccccc2)sc2nc3cccnc3n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(=Cc2ccccc2)sc2nc3cccnc3n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

7-Bromo-2-(4-fluorobenzylidene)[1,3]thiazolo[2',3':2,3]imidazo[4,5-b]pyridin-3(2H)-one chemical structure, C15H7BrFN3OS, CAS 328962-44-3
7-Bromo-2-(4-fluorobenzylidene)[1,3]thiazolo[2',3':2,3]imidazo[4,5-b]pyridin-3(2H)-one
CAS 328962-44-3C15H7BrFN3OS
Bas 00343688 chemical structure, C16H10BrN3O2S, CAS 5669-49-8
Bas 00343688
CAS 5669-49-8C16H10BrN3O2S
7-Bromo-2-(3-bromobenzylidene)[1,3]thiazolo[2',3':2,3]imidazo[4,5-b]pyridin-3(2H)-one chemical structure, C15H7Br2N3OS, CAS 5671-09-0
7-Bromo-2-(3-bromobenzylidene)[1,3]thiazolo[2',3':2,3]imidazo[4,5-b]pyridin-3(2H)-one
CAS 5671-09-0C15H7Br2N3OS
(2Z)-7-Bromo-2-[4-(dimethylamino)benzylidene][1,3]thiazolo[2',3':2,3]imidazo[4,5-b]pyridin-3(2H)-one chemical structure, C17H13BrN4OS, CAS 343591-66-2
(2Z)-7-Bromo-2-[4-(dimethylamino)benzylidene][1,3]thiazolo[2',3':2,3]imidazo[4,5-b]pyridin-3(2H)-one
CAS 343591-66-2C17H13BrN4OS