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Murcko scaffold

Ring system with 3 rings and 25 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
5
With full pages
5
Scaffold SMILES

O=C(CCc1ccccc1)NCC(=O)Nc1ccc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1ccccc1)NCC(=O)Nc1ccc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

Phenylalanine arginine beta-naphthylamide chemical structure, C25H30N6O2, CAS 115871-02-8
Phenylalanine arginine beta-naphthylamide
CAS 115871-02-8C25H30N6O2
H-Phe-Gly-bNA chemical structure, C21H21N3O2, CAS 370582-00-6
H-Phe-Gly-bNA
CAS 370582-00-6C21H21N3O2
Phenylalanyl-N~5~-(diaminomethylidene)-N-naphthalen-2-ylornithinamide--hydrogen chloride (1/1) chemical structure, C25H31ClN6O2, CAS 100929-99-5
Phenylalanyl-N~5~-(diaminomethylidene)-N-naphthalen-2-ylornithinamide--hydrogen chloride (1/1)
CAS 100929-99-5C25H31ClN6O2
H-Ala-Leu-Tyr-Leu-bNA chemical structure, C34H45N5O5, CAS 201985-44-6
H-Ala-Leu-Tyr-Leu-bNA
CAS 201985-44-6C34H45N5O5
H-Val-Tyr-Ser-bNA chemical structure, C27H32N4O5, CAS 13989-68-9
H-Val-Tyr-Ser-bNA
CAS 13989-68-9C27H32N4O5