CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
4
With full pages
2
Scaffold SMILES

c1ccc(OCCCNCCc2ccc3ccccc3c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(OCCCNCCc2ccc3ccccc3c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

Nps-2143 chemical structure, C24H25ClN2O2, CAS 284035-33-2
Nps-2143
CAS 284035-33-2C24H25ClN2O2
NPS-2143 hydrochloride chemical structure, C24H26Cl2N2O2, CAS 324523-20-8
NPS-2143 hydrochloride
CAS 324523-20-8C24H26Cl2N2O2
Benzenepropanoic acid, 3-cyano-4-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-, (Hydrochloride) (1:1) chemical structure, C27H31ClN2O4, CAS 1192845-63-8
Benzenepropanoic acid, 3-cyano-4-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-, (Hydrochloride) (1:1)
CAS 1192845-63-8C27H31ClN2O4
Benzenepropanoic acid,3-cyano-4-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-,ethyl ester,(Hydrochloride) (1:1) chemical structure, C29H35ClN2O4, CAS 1192845-62-7
Benzenepropanoic acid,3-cyano-4-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino]-2-hydroxypropoxy]-,ethyl ester,(Hydrochloride) (1:1)
CAS 1192845-62-7C29H35ClN2O4