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Murcko scaffold

Ring system with 3 rings and 16 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
12
With full pages
2
Scaffold SMILES

c1cc(Nc2ccc3cn[nH]c3c2)ncn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(Nc2ccc3cn[nH]c3c2)ncn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-(1H-Indazol-6-ylamino)-2-methylsulfanyl-pyrimidine-5-carboxamide chemical structure, C13H12N6OS, CAS 342636-96-8
4-(1H-Indazol-6-ylamino)-2-methylsulfanyl-pyrimidine-5-carboxamide
CAS 342636-96-8C13H12N6OS
N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine chemical structure, C14H14ClN5, CAS 444731-75-3
N-(2-Chloro-4-pyrimidinyl)-N,2,3-trimethyl-2H-indazol-6-amine
CAS 444731-75-3C14H14ClN5
N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine chemical structure, C13H12ClN5, CAS 444731-74-2
N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine
CAS 444731-74-2C13H12ClN5
Pazopanib impurity 90 chemical structure, C13H12ClN5, CAS 2369664-23-1
Pazopanib impurity 90
CAS 2369664-23-1C13H12ClN5
N-(2-Chloro-4-pyrimidinyl)-N-(3-methyl-1H-indazol-6-yl)amine chemical structure, C12H10ClN5, CAS 444731-66-2
N-(2-Chloro-4-pyrimidinyl)-N-(3-methyl-1H-indazol-6-yl)amine
CAS 444731-66-2C12H10ClN5
tert-Butyl 6-(2-chloropyrimidin-4-ylamino)-3-methyl-1H-indazole-1-carboxylate chemical structure, C17H18ClN5O2, CAS 444731-68-4
tert-Butyl 6-(2-chloropyrimidin-4-ylamino)-3-methyl-1H-indazole-1-carboxylate
CAS 444731-68-4C17H18ClN5O2
Pazopanib impurity 23 chemical structure, C16H20N6, CAS 1296888-46-4
Pazopanib impurity 23
CAS 1296888-46-4C16H20N6
N-(2-Methoxypyrimidin-4-yl)-N-methyl-2,3-dimethyl-2-H-indazol-6-amine chemical structure, C15H17N5O, CAS 1296888-47-5
N-(2-Methoxypyrimidin-4-yl)-N-methyl-2,3-dimethyl-2-H-indazol-6-amine
CAS 1296888-47-5C15H17N5O
N-(2-Chloro-5-methoxypyrimidin-4-yl)-1H-indazol-6-amine chemical structure, C12H10ClN5O, CAS 1447607-39-7
N-(2-Chloro-5-methoxypyrimidin-4-yl)-1H-indazol-6-amine
CAS 1447607-39-7C12H10ClN5O
N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methyl-2,4-pyrimidinediamine chemical structure, C14H16N6, CAS 1821666-71-0
N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methyl-2,4-pyrimidinediamine
CAS 1821666-71-0C14H16N6
N-(2-Chloro-5-methylpyrimidin-4-yl)-1H-indazol-6-amine chemical structure, C12H10ClN5, CAS 2454699-18-2
N-(2-Chloro-5-methylpyrimidin-4-yl)-1H-indazol-6-amine
CAS 2454699-18-2C12H10ClN5
N-(2-Methoxypyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine chemical structure, C14H15N5O, CAS 2369664-16-2
N-(2-Methoxypyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine
CAS 2369664-16-2C14H15N5O