Murcko scaffold
(3S-Trans)-3-benzylhexahydropyrrolo(1,2-a)pyrazine-1,4-dione scaffold
10 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 10
- With full pages
- 6
Scaffold SMILES
O=C1NC(Cc2ccccc2)C(=O)N2CCCC12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 10 of 10 chemicals
(3S-Trans)-3-benzylhexahydropyrrolo(1,2-a)pyrazine-1,4-dione
CAS 14705-60-3C14H16N2O2
Cyclo(L-Pro-L-Tyr)
CAS 4549-02-4C14H16N2O3
Cyclo(phenylalanyl-4-fluoro-prolyl)
CAS 131176-01-7C14H15FN2O2
3-((4-Hydroxyphenyl)methyl)-2,3,6,7,8,8a-hexahydropyrrolo(1,2-a)pyrazine-1,4-dione
CAS 5654-84-2C14H16N2O3
Cyclo(L-Phe-L-Pro)
CAS 3705-26-8C14H16N2O2
(3S,8aS)-Hexahydro-2-methyl-3-(phenylmethyl)pyrrolo(1,2-a)pyrazine-1,4-dione
CAS 37553-66-5C15H18N2O2
Phenylalanyl-prolyl diketopiperazine
CAS 26488-24-4C14H16N2O2
Cyclo-(L-phenylalanyl-4R-hydroxy-L-proline)
CAS 118477-06-8C14H16N2O3
Cyclo(phe-hpro)
CAS 1016899-94-7C14H16N2O3
Cyclo(tyr-hpro)
CAS 813461-21-1C14H16N2O4