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Murcko scaffold

Ring system with 4 rings and 10 atoms

17 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 10
Chemicals: 17
With full pages: 6

Scaffold SMILES

C1COB(C23CC(C2)C3)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold C1COB(C23CC(C2)C3)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

2-[3-(2,2-Difluoroethyl)bicyclo[1.1.1]pentan-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C12H18BF3O2, CAS 2410440-14-9

2-[3-(2,2-Difluoroethyl)bicyclo[1.1.1]pentan-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CAS 2410440-14-9C₁₂H₁₈BF₃O₂

2-(Bicyclo(1.1.1)pentan-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C11H19BO2, CAS 2152645-07-1

2-(Bicyclo(1.1.1)pentan-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CAS 2152645-07-1C₁₁H₁₉BO₂

tert-Butyl N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-bicyclo[1.1.1]pentanyl]carbamate chemical structure, C16H28BNO4, CAS 2195389-86-5

tert-Butyl N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-bicyclo[1.1.1]pentanyl]carbamate

CAS 2195389-86-5C₁₆H₂₈BNO₄

Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-carboxylate chemical structure, C13H21BO4, CAS 2410440-12-7

Methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-carboxylate

CAS 2410440-12-7C₁₃H₂₁BO₄

4,4,5,5-Tetramethyl-2-{3-methylbicyclo[1.1.1]pentan-1-yl}-1,3,2-dioxaborolane chemical structure, C12H21BO2, CAS 3070539-24-8

4,4,5,5-Tetramethyl-2-{3-methylbicyclo[1.1.1]pentan-1-yl}-1,3,2-dioxaborolane

CAS 3070539-24-8C₁₂H₂₁BO₂

2-[3-(1,1-Difluoroethyl)bicyclo[1.1.1]pentan-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C13H21BF2O2, CAS 3070539-38-4

2-[3-(1,1-Difluoroethyl)bicyclo[1.1.1]pentan-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CAS 3070539-38-4C₁₃H₂₁BF₂O₂

2-[3-(2,2-Difluoroethyl)-1-bicyclo[1.1.1]pentanyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C13H21BF2O2, CAS 3070539-30-6

2-[3-(2,2-Difluoroethyl)-1-bicyclo[1.1.1]pentanyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CAS 3070539-30-6C₁₃H₂₁BF₂O₂

4,4,5,5-Tetramethyl-2-[3-(2,2,2-trifluoroethyl)bicyclo[1.1.1]pentan-1-yl]-1,3,2-dioxaborolane chemical structure, C13H20BF3O2, CAS 2826264-05-3

4,4,5,5-Tetramethyl-2-[3-(2,2,2-trifluoroethyl)bicyclo[1.1.1]pentan-1-yl]-1,3,2-dioxaborolane

CAS 2826264-05-3C₁₃H₂₀BF₃O₂

2-[3-(Difluoromethyl)bicyclo[1.1.1]pentan-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C12H19BF2O2, CAS 3061854-72-3

2-[3-(Difluoromethyl)bicyclo[1.1.1]pentan-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CAS 3061854-72-3C₁₂H₁₉BF₂O₂

tert-Butyl (2-butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)carbamate chemical structure, C20H36BNO4, CAS 2609867-07-2

tert-Butyl (2-butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)carbamate

CAS 2609867-07-2C₂₀H₃₆BNO₄

2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)ethan-1-ol chemical structure, C13H23BO3, CAS 2784646-57-5

2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)ethan-1-ol

CAS 2784646-57-5C₁₃H₂₃BO₃

(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)methanol chemical structure, C12H21BO3, CAS 2784646-56-4

(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)methanol

CAS 2784646-56-4C₁₂H₂₁BO₃

tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-carboxylate chemical structure, C16H27BO4, CAS 2784646-58-6

tert-Butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-carboxylate

CAS 2784646-58-6C₁₆H₂₇BO₄

tert-Butyl 2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)acetate chemical structure, C17H29BO4, CAS 2784646-59-7

tert-Butyl 2-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentan-1-yl)acetate

CAS 2784646-59-7C₁₇H₂₉BO₄

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-sulfonamide chemical structure, C11H20BNO4S, CAS 2784646-62-2

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-sulfonamide

CAS 2784646-62-2C₁₁H₂₀BNO₄S

2-(3-(Bromomethyl)bicyclo[1.1.1]pentan-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane chemical structure, C12H20BBrO2, CAS 2784646-55-3

2-(3-(Bromomethyl)bicyclo[1.1.1]pentan-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CAS 2784646-55-3C₁₂H₂₀BBrO₂

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-carbonitrile chemical structure, C12H18BNO2, CAS 2410440-13-8

3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[1.1.1]pentane-1-carbonitrile

CAS 2410440-13-8C₁₂H₁₈BNO₂