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Murcko scaffold

3-{Bicyclo[1.1.1]pentan-1-yl}pyrrolidine scaffold

31 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
10
Chemicals
31
With full pages
4
Scaffold SMILES

C1CC(C23CC(C2)C3)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-{Bicyclo[1.1.1]pentan-1-yl}pyrrolidine page
Murcko scaffold C1CC(C23CC(C2)C3)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

3-{Bicyclo[1.1.1]pentan-1-yl}pyrrolidine hydrochloride chemical structure, C9H16ClN, CAS 2377035-24-8
3-{Bicyclo[1.1.1]pentan-1-yl}pyrrolidine hydrochloride
CAS 2377035-24-8C9H16ClN
3-{Bicyclo[1.1.1]pentan-1-yl}pyrrolidine chemical structure, C9H15N, CAS 2377035-23-7
3-{Bicyclo[1.1.1]pentan-1-yl}pyrrolidine
CAS 2377035-23-7C9H15N
(2S)-4-{Bicyclo[1.1.1]pentan-1-yl}-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid chemical structure, C15H23NO4, CAS 2377030-48-1
(2S)-4-{Bicyclo[1.1.1]pentan-1-yl}-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid
CAS 2377030-48-1C15H23NO4
tert-Butyl 3-{3-iodobicyclo[1.1.1]pentan-1-yl}pyrrolidine-1-carboxylate chemical structure, C14H22INO2, CAS 2742660-38-2
tert-Butyl 3-{3-iodobicyclo[1.1.1]pentan-1-yl}pyrrolidine-1-carboxylate
CAS 2742660-38-2C14H22INO2
3-(1-((tert-Butoxy)carbonyl)pyrrolidin-3-yl)bicyclo(1.1.1)pentane-1-carboxylic acid chemical structure, C15H23NO4, CAS 2770358-68-2
3-(1-((tert-Butoxy)carbonyl)pyrrolidin-3-yl)bicyclo(1.1.1)pentane-1-carboxylic acid
CAS 2770358-68-2C15H23NO4
tert-Butyl 3-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-1-carboxylate chemical structure, C14H23NO2, CAS 2680536-34-7
tert-Butyl 3-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-1-carboxylate
CAS 2680536-34-7C14H23NO2
1-tert-Butyl 2-methyl (2S)-4-{3-iodobicyclo[1.1.1]pentan-1-yl}pyrrolidine-1,2-dicarboxylate chemical structure, C16H24INO4, CAS 2792183-52-7
1-tert-Butyl 2-methyl (2S)-4-{3-iodobicyclo[1.1.1]pentan-1-yl}pyrrolidine-1,2-dicarboxylate
CAS 2792183-52-7C16H24INO4
3-(Pyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylic acid chemical structure, C10H15NO2, CAS 2803827-37-2
3-(Pyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylic acid
CAS 2803827-37-2C10H15NO2
3-[1-(2,2,2-Trifluoroacetyl)pyrrolidin-3-yl]bicyclo[1.1.1]pentane-1-carboxylic acid chemical structure, C12H14F3NO3, CAS 2803828-26-2
3-[1-(2,2,2-Trifluoroacetyl)pyrrolidin-3-yl]bicyclo[1.1.1]pentane-1-carboxylic acid
CAS 2803828-26-2C12H14F3NO3
3-{1-[(Prop-2-en-1-yloxy)carbonyl]pyrrolidin-3-yl}bicyclo[1.1.1]pentane-1-carboxylic acid chemical structure, C14H19NO4, CAS 2803834-19-5
3-{1-[(Prop-2-en-1-yloxy)carbonyl]pyrrolidin-3-yl}bicyclo[1.1.1]pentane-1-carboxylic acid
CAS 2803834-19-5C14H19NO4
3-(1-Acetylpyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylic acid chemical structure, C12H17NO3, CAS 2803852-70-0
3-(1-Acetylpyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylic acid
CAS 2803852-70-0C12H17NO3
Methyl 3-(pyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylate chemical structure, C11H17NO2, CAS 2803860-76-4
Methyl 3-(pyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylate
CAS 2803860-76-4C11H17NO2
Ethyl 3-(pyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylate chemical structure, C12H19NO2, CAS 2803823-41-6
Ethyl 3-(pyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylate
CAS 2803823-41-6C12H19NO2
tert-Butyl 3-(pyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylate chemical structure, C14H23NO2, CAS 2803833-52-3
tert-Butyl 3-(pyrrolidin-3-yl)bicyclo[1.1.1]pentane-1-carboxylate
CAS 2803833-52-3C14H23NO2
Methyl (2S)-4-{3-iodobicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylate chemical structure, C11H16INO2, CAS 2803776-50-1
Methyl (2S)-4-{3-iodobicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylate
CAS 2803776-50-1C11H16INO2
1-Boc-3-(3-hydroxybicyclo[1.1.1]pentan-1-yl)pyrrolidine chemical structure, C14H23NO3, CAS 2751620-69-4
1-Boc-3-(3-hydroxybicyclo[1.1.1]pentan-1-yl)pyrrolidine
CAS 2751620-69-4C14H23NO3
tert-Butyl 3-{3-formylbicyclo[1.1.1]pentan-1-yl}pyrrolidine-1-carboxylate chemical structure, C15H23NO3, CAS 2866335-06-8
tert-Butyl 3-{3-formylbicyclo[1.1.1]pentan-1-yl}pyrrolidine-1-carboxylate
CAS 2866335-06-8C15H23NO3
Ethyl (2S)-4-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylate chemical structure, C12H19NO2, CAS 2580128-41-0
Ethyl (2S)-4-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylate
CAS 2580128-41-0C12H19NO2
Methyl (2S)-4-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylate chemical structure, C11H17NO2, CAS 2580128-20-5
Methyl (2S)-4-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylate
CAS 2580128-20-5C11H17NO2
(2S)-4-{Bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylic acid chemical structure, C10H15NO2, CAS 2580128-72-7
(2S)-4-{Bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylic acid
CAS 2580128-72-7C10H15NO2
tert-Butyl (2S)-4-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylate chemical structure, C14H23NO2, CAS 2639399-11-2
tert-Butyl (2S)-4-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylate
CAS 2639399-11-2C14H23NO2
(2S)-4-{Bicyclo[1.1.1]pentan-1-yl}-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carboxylic acid chemical structure, C12H14F3NO3, CAS 2680521-56-4
(2S)-4-{Bicyclo[1.1.1]pentan-1-yl}-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carboxylic acid
CAS 2680521-56-4C12H14F3NO3
(2S)-4-{Bicyclo[1.1.1]pentan-1-yl}-1-[(prop-2-en-1-yloxy)carbonyl]pyrrolidine-2-carboxylic acid chemical structure, C14H19NO4, CAS 2680521-11-1
(2S)-4-{Bicyclo[1.1.1]pentan-1-yl}-1-[(prop-2-en-1-yloxy)carbonyl]pyrrolidine-2-carboxylic acid
CAS 2680521-11-1C14H19NO4
(2S)-1-Acetyl-4-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylic acid chemical structure, C12H17NO3, CAS 2680520-91-4
(2S)-1-Acetyl-4-{bicyclo[1.1.1]pentan-1-yl}pyrrolidine-2-carboxylic acid
CAS 2680520-91-4C12H17NO3