CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 25 atoms

44 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
44
With full pages
6
Scaffold SMILES

O=C(c1ccccc1)N1CCC(Nc2ccccc2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1CCC(Nc2ccccc2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 44 of 44 chemicals

(4-Anilino-2-methyl-3,4-dihydroquinolin-1(2H)-yl)(phenyl)methanone chemical structure, C23H22N2O, CAS 857-45-4
(4-Anilino-2-methyl-3,4-dihydroquinolin-1(2H)-yl)(phenyl)methanone
CAS 857-45-4C23H22N2O
(3-Methoxyphenyl)[2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]methanone chemical structure, C24H24N2O2, CAS 295360-58-6
(3-Methoxyphenyl)[2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]methanone
CAS 295360-58-6C24H24N2O2
(4-Methoxy-phenyl)-(2-methyl-4-phenylamino-3,4-dihydro-2H-quinolin-1-yl)-methanone chemical structure, C24H24N2O2, CAS 300801-69-8
(4-Methoxy-phenyl)-(2-methyl-4-phenylamino-3,4-dihydro-2H-quinolin-1-yl)-methanone
CAS 300801-69-8C24H24N2O2
[4-Anilino-2-methyl-3,4-dihydro-1(2H)-quinolinyl](4-chlorophenyl)methanone chemical structure, C23H21ClN2O, CAS 303226-75-7
[4-Anilino-2-methyl-3,4-dihydro-1(2H)-quinolinyl](4-chlorophenyl)methanone
CAS 303226-75-7C23H21ClN2O
(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(4-propylphenyl)methanone chemical structure, C26H28N2O, CAS 332043-88-6
(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(4-propylphenyl)methanone
CAS 332043-88-6C26H28N2O
(3,4-Dichlorophenyl)[2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]methanone chemical structure, C23H20Cl2N2O, CAS 309287-37-4
(3,4-Dichlorophenyl)[2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]methanone
CAS 309287-37-4C23H20Cl2N2O
N-((2S,4R)-1-Benzoyl-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylacetamide chemical structure, C25H24N2O2
N-((2S,4R)-1-Benzoyl-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylacetamide
C25H24N2O2
N-(1-Benzoyl-2-methyl-1,2,3,4-tetrahydro-quinolin-4-yl)-N-phenyl-acetamide chemical structure, C25H24N2O2, CAS 1202402-30-9
N-(1-Benzoyl-2-methyl-1,2,3,4-tetrahydro-quinolin-4-yl)-N-phenyl-acetamide
CAS 1202402-30-9C25H24N2O2
(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(3-fluorophenyl)methanone chemical structure, C23H21FN2O, CAS 296272-59-8
(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(3-fluorophenyl)methanone
CAS 296272-59-8C23H21FN2O
(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(4-tert-butylphenyl)methanone chemical structure, C27H30N2O, CAS 295360-63-3
(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(4-tert-butylphenyl)methanone
CAS 295360-63-3C27H30N2O
N-[1-(3-Methoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinyl]-N-phenylacetamide chemical structure, C26H26N2O3, CAS 295360-57-5
N-[1-(3-Methoxybenzoyl)-2-methyl-1,2,3,4-tetrahydro-4-quinolinyl]-N-phenylacetamide
CAS 295360-57-5C26H26N2O3
(2-Bromophenyl)[2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]methanone chemical structure, C23H21BrN2O, CAS 295363-89-2
(2-Bromophenyl)[2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]methanone
CAS 295363-89-2C23H21BrN2O
{2,8-Dimethyl-4-[(2-methylphenyl)amino]-3,4-dihydroquinolin-1(2H)-yl}(3-methylphenyl)methanone chemical structure, C26H28N2O, CAS 414908-20-6
{2,8-Dimethyl-4-[(2-methylphenyl)amino]-3,4-dihydroquinolin-1(2H)-yl}(3-methylphenyl)methanone
CAS 414908-20-6C26H28N2O
[2,6-Dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]-(4-fluorophenyl)methanone chemical structure, C25H25FN2O, CAS 352021-06-8
[2,6-Dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]-(4-fluorophenyl)methanone
CAS 352021-06-8C25H25FN2O
(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(3-bromophenyl)methanone chemical structure, C23H21BrN2O, CAS 304879-90-1
(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-(3-bromophenyl)methanone
CAS 304879-90-1C23H21BrN2O
{2,6-Dimethyl-4-[(4-methylphenyl)amino]-3,4-dihydroquinolin-1(2H)-yl}(3-nitrophenyl)methanone chemical structure, C25H25N3O3, CAS 331973-79-6
{2,6-Dimethyl-4-[(4-methylphenyl)amino]-3,4-dihydroquinolin-1(2H)-yl}(3-nitrophenyl)methanone
CAS 331973-79-6C25H25N3O3
[2,6-Dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]-(3-fluorophenyl)methanone chemical structure, C25H25FN2O, CAS 317842-79-8
[2,6-Dimethyl-4-(4-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]-(3-fluorophenyl)methanone
CAS 317842-79-8C25H25FN2O
1-(4-Methoxybenzoyl)-2,6-dimethyl-N-(4-methylphenyl)-1,2,3,4-tetrahydro-4-quinolinamine chemical structure, C26H28N2O2, CAS 5680-89-7
1-(4-Methoxybenzoyl)-2,6-dimethyl-N-(4-methylphenyl)-1,2,3,4-tetrahydro-4-quinolinamine
CAS 5680-89-7C26H28N2O2
(2,4-Dichlorophenyl)[2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]methanone chemical structure, C23H20Cl2N2O, CAS 328286-53-9
(2,4-Dichlorophenyl)[2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]methanone
CAS 328286-53-9C23H20Cl2N2O
2,8-Dimethyl-1-(4-methylbenzoyl)-N-(2-methylphenyl)-1,2,3,4-tetrahydro-4-quinolinamine chemical structure, C26H28N2O, CAS 300590-07-2
2,8-Dimethyl-1-(4-methylbenzoyl)-N-(2-methylphenyl)-1,2,3,4-tetrahydro-4-quinolinamine
CAS 300590-07-2C26H28N2O
[2,8-Dimethyl-4-(2-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]-phenylmethanone chemical structure, C25H26N2O, CAS 331640-16-5
[2,8-Dimethyl-4-(2-methylanilino)-3,4-dihydro-2H-quinolin-1-yl]-phenylmethanone
CAS 331640-16-5C25H26N2O
(4-Anilino-2,8-dimethyl-3,4-dihydro-2H-quinolin-1-yl)-(2-methylphenyl)methanone chemical structure, C25H26N2O, CAS 332044-08-3
(4-Anilino-2,8-dimethyl-3,4-dihydro-2H-quinolin-1-yl)-(2-methylphenyl)methanone
CAS 332044-08-3C25H26N2O
(2-Methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl)(2-nitrophenyl)methanone chemical structure, C23H21N3O3, CAS 296244-34-3
(2-Methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl)(2-nitrophenyl)methanone
CAS 296244-34-3C23H21N3O3
{2,8-Dimethyl-4-[(4-methylphenyl)amino]-3,4-dihydroquinolin-1(2H)-yl}(2-methylphenyl)methanone chemical structure, C26H28N2O, CAS 314039-33-3
{2,8-Dimethyl-4-[(4-methylphenyl)amino]-3,4-dihydroquinolin-1(2H)-yl}(2-methylphenyl)methanone
CAS 314039-33-3C26H28N2O