CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 27 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
10
With full pages
3
Scaffold SMILES

O=c1c2ccccc2nc(-c2ccccc2)n1CCCOc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2nc(-c2ccccc2)n1CCCOc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-(4-Chlorophenyl)-3-[3-(2-nitrophenoxy)propyl]quinazolin-4-one chemical structure, C23H18ClN3O4, CAS 381710-40-3
2-(4-Chlorophenyl)-3-[3-(2-nitrophenoxy)propyl]quinazolin-4-one
CAS 381710-40-3C23H18ClN3O4
3-[3-(2-Chlorophenoxy)propyl]-2-(4-chlorophenyl)quinazolin-4-one chemical structure, C23H18Cl2N2O2, CAS 378756-54-8
3-[3-(2-Chlorophenoxy)propyl]-2-(4-chlorophenyl)quinazolin-4-one
CAS 378756-54-8C23H18Cl2N2O2
2-(4-Chlorophenyl)-3-[3-(2-methoxy-4-methylphenoxy)propyl]quinazolin-4-one chemical structure, C25H23ClN2O3, CAS 421580-47-4
2-(4-Chlorophenyl)-3-[3-(2-methoxy-4-methylphenoxy)propyl]quinazolin-4-one
CAS 421580-47-4C25H23ClN2O3
3-[3-(2-Bromophenoxy)propyl]-2-(4-chlorophenyl)quinazolin-4-one chemical structure, C23H18BrClN2O2, CAS 380593-22-6
3-[3-(2-Bromophenoxy)propyl]-2-(4-chlorophenyl)quinazolin-4-one
CAS 380593-22-6C23H18BrClN2O2
2-(4-Chlorophenyl)-3-[3-(3-methylphenoxy)propyl]quinazolin-4-one chemical structure, C24H21ClN2O2, CAS 381206-90-2
2-(4-Chlorophenyl)-3-[3-(3-methylphenoxy)propyl]quinazolin-4-one
CAS 381206-90-2C24H21ClN2O2
2-(4-Chlorophenyl)-3-[3-(4-fluorophenoxy)propyl]quinazolin-4-one chemical structure, C23H18ClFN2O2, CAS 381170-52-1
2-(4-Chlorophenyl)-3-[3-(4-fluorophenoxy)propyl]quinazolin-4-one
CAS 381170-52-1C23H18ClFN2O2
Methyl 4-[3-[2-(4-chlorophenyl)-4-oxoquinazolin-3-yl]propoxy]benzoate chemical structure, C25H21ClN2O4, CAS 381703-02-2
Methyl 4-[3-[2-(4-chlorophenyl)-4-oxoquinazolin-3-yl]propoxy]benzoate
CAS 381703-02-2C25H21ClN2O4
2-(4-Chlorophenyl)-3-[3-(2-methylphenoxy)propyl]quinazolin-4-one chemical structure, C24H21ClN2O2, CAS 380880-36-4
2-(4-Chlorophenyl)-3-[3-(2-methylphenoxy)propyl]quinazolin-4-one
CAS 380880-36-4C24H21ClN2O2
2-(4-Chlorophenyl)-3-[3-(4-nitrophenoxy)propyl]quinazolin-4-one chemical structure, C23H18ClN3O4, CAS 432015-09-3
2-(4-Chlorophenyl)-3-[3-(4-nitrophenoxy)propyl]quinazolin-4-one
CAS 432015-09-3C23H18ClN3O4
2-(4-Chlorophenyl)-3-[3-(2-methoxyphenoxy)propyl]quinazolin-4-one chemical structure, C24H21ClN2O3, CAS 381684-77-1
2-(4-Chlorophenyl)-3-[3-(2-methoxyphenoxy)propyl]quinazolin-4-one
CAS 381684-77-1C24H21ClN2O3