Murcko scaffold
2-Benzylsulfanylpyridine scaffold
308 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 308
- With full pages
- 50
Scaffold SMILES
c1ccc(CSc2ccccn2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 308 chemicals
2-Benzylsulfanylpyridine
CAS 51290-79-0C12H11NS
![2-[(2-Methoxyphenyl)methylsulfanyl]pyridine chemical structure, C13H13NOS, CAS 646511-45-7](/s/LUDKKYMCVVUYAJ-UHFFFAOYSA-N.svg)
2-[(2-Methoxyphenyl)methylsulfanyl]pyridine
CAS 646511-45-7C13H13NOS
![2-[(3-Methoxyphenyl)methylsulfanyl]pyridine chemical structure, C13H13NOS, CAS 646511-46-8](/s/IWUUDXIPCUTSLO-UHFFFAOYSA-N.svg)
2-[(3-Methoxyphenyl)methylsulfanyl]pyridine
CAS 646511-46-8C13H13NOS
![Pyridine, 2-[[(4-methylphenyl)methyl]thio]- chemical structure, C13H13NS, CAS 112498-21-2](/s/XUIAEUARFVMQJD-UHFFFAOYSA-N.svg)
Pyridine, 2-[[(4-methylphenyl)methyl]thio]-
CAS 112498-21-2C13H13NS
![Pyridine, 2-[[(3-methylphenyl)methyl]thio]- chemical structure, C13H13NS, CAS 646511-51-5](/s/IHIXPSUNZJYCKL-UHFFFAOYSA-N.svg)
Pyridine, 2-[[(3-methylphenyl)methyl]thio]-
CAS 646511-51-5C13H13NS
![Pyridine, 2-[[(2-methylphenyl)methyl]thio]- chemical structure, C13H13NS, CAS 646511-49-1](/s/ZTCZXISLKBBSPT-UHFFFAOYSA-N.svg)
Pyridine, 2-[[(2-methylphenyl)methyl]thio]-
CAS 646511-49-1C13H13NS
2-Benzylsulfanylpyridine-4-carbonitrile
CAS 180791-02-0C13H10N2S
![2-[(2-Chlorophenyl)methylsulfanyl]pyridine-4-carbonitrile chemical structure, C13H9ClN2S, CAS 249553-05-7](/s/FNDFMQBILFXGDT-UHFFFAOYSA-N.svg)
2-[(2-Chlorophenyl)methylsulfanyl]pyridine-4-carbonitrile
CAS 249553-05-7C13H9ClN2S
2-Benzylsulfanyl-1-oxidopyridin-1-ium
CAS 3915-60-4C12H11NOS
![2-(1-[2,5-Dimethylphenyl]-ethylthio)pyridine N-oxide chemical structure, C15H17NOS, CAS 60263-87-8](/s/NNMVGDTXYHAECL-UHFFFAOYSA-N.svg)
2-(1-[2,5-Dimethylphenyl]-ethylthio)pyridine N-oxide
CAS 60263-87-8C15H17NOS
2-Benzylsulfanyl-3-methoxy-pyridine
CAS 500163-12-2C13H13NOS
![3-Pyridinecarbonitrile, 2-[(phenylmethyl)thio]- chemical structure, C13H10N2S, CAS 89407-37-4](/s/XMKZNELJNRWNDM-UHFFFAOYSA-N.svg)
3-Pyridinecarbonitrile, 2-[(phenylmethyl)thio]-
CAS 89407-37-4C13H10N2S
![2-[(2,5-Dimethylphenyl)methylsulfanyl]pyridin-3-ol chemical structure, C14H15NOS, CAS 500163-28-0](/s/LXWBPNCRFBCIHV-UHFFFAOYSA-N.svg)
2-[(2,5-Dimethylphenyl)methylsulfanyl]pyridin-3-ol
CAS 500163-28-0C14H15NOS
2-(Benzylthio)-3-nitropyridine
CAS 69212-31-3C12H10N2O2S
5-Acetyl-2-(benzylsulfanyl)-6-methylnicotinonitrile
CAS 337922-63-1C16H14N2OS
![2-[(6-Amino-3,5-dicyano-4-ethylpyridin-2-yl)sulfanyl]-2-phenylacetamide chemical structure, C17H15N5OS, CAS 184530-72-1](/s/FGQIKVMUUPNDOL-UHFFFAOYSA-N.svg)
2-[(6-Amino-3,5-dicyano-4-ethylpyridin-2-yl)sulfanyl]-2-phenylacetamide
CAS 184530-72-1C17H15N5OS
![2-[(4-Nitrophenyl)methylsulfanyl]pyridine-3-carboxylic acid chemical structure, C13H10N2O4S, CAS 304475-38-5](/s/LFALEDFUNKOOBJ-UHFFFAOYSA-N.svg)
2-[(4-Nitrophenyl)methylsulfanyl]pyridine-3-carboxylic acid
CAS 304475-38-5C13H10N2O4S
![4-Methoxy-3-[(pyridin-2-ylsulfanyl)methyl]benzaldehyde chemical structure, C14H13NO2S, CAS 327047-73-4](/s/ZNIMAFXWOSZUPB-UHFFFAOYSA-N.svg)
4-Methoxy-3-[(pyridin-2-ylsulfanyl)methyl]benzaldehyde
CAS 327047-73-4C14H13NO2S
![2-[(4-Nitrobenzyl)sulfanyl]pyridine chemical structure, C12H10N2O2S, CAS 104742-05-4](/s/SAGZPBGIVZXYBE-UHFFFAOYSA-N.svg)
2-[(4-Nitrobenzyl)sulfanyl]pyridine
CAS 104742-05-4C12H10N2O2S
2-(Benzylthio)-4,5,6-trimethylnicotinonitrile
CAS 151693-77-5C16H16N2S
2-Benzylsulfanyl-4-methoxymethyl-6-methyl-nicotinonitrile
CAS 30820-94-1C16H16N2OS
![4-[(Pyridin-2-ylthio)methyl]benzoic acid chemical structure, C13H11NO2S, CAS 82145-80-0](/s/WVJPZRUUOGYPAV-UHFFFAOYSA-N.svg)
4-[(Pyridin-2-ylthio)methyl]benzoic acid
CAS 82145-80-0C13H11NO2S
![2-[(2-Chlorobenzyl)sulfanyl]-4,6-dimethylnicotinonitrile chemical structure, C15H13ClN2S, CAS 311333-14-9](/s/PBBYZSMOXFRDSN-UHFFFAOYSA-N.svg)
2-[(2-Chlorobenzyl)sulfanyl]-4,6-dimethylnicotinonitrile
CAS 311333-14-9C15H13ClN2S
![2-{[(4-Chlorophenyl)methyl]sulfanyl}-4,6-dimethylpyridine-3-carbonitrile chemical structure, C15H13ClN2S, CAS 312758-03-5](/s/IUZXSGUVMSCXBF-UHFFFAOYSA-N.svg)
2-{[(4-Chlorophenyl)methyl]sulfanyl}-4,6-dimethylpyridine-3-carbonitrile
CAS 312758-03-5C15H13ClN2S
- 2-[(4-Methoxy-3-nitrobenzyl)sulfanyl]pyridine311317-58-5C13H12N2O3S
- 2-[(4-Bromophenyl)methylsulfanyl]-4,6-dimethylpyridine-3-carbonitrile332109-99-6C15H13BrN2S
- 2-(Benzylsulfanyl)-4,6-dimethylnicotinonitrile97248-85-6C15H14N2S
- 4,6-Dimethyl-2-[(4-methylphenyl)methylsulfanyl]pyridine-3-carbonitrile371207-12-4C16H16N2S
- 3-Chloro-4-(2-pyridylthiomethyl)benzenecarbonitrile346464-55-9C13H9ClN2S
- 2-[(2-Chlorophenyl)methylsulfanyl]-4-(dimethylamino)pyridine-3-carbonitrile368888-54-4C15H14ClN3S
- 2-{[(2-Chlorophenyl)methyl]sulfanyl}pyridine-3-carboxylic acid422540-99-6C13H10ClNO2S
- 2 suppliers3-Pyridinecarboxylic acid, 2-[(phenylmethyl)thio]-112811-90-2C13H11NO2S
- 2-[(2-Fluorophenyl)methylsulfanyl]-6-methylpyridine-3-carbonitrile316358-70-0C14H11FN2S
- 2-[(2,4-Dichlorobenzyl)sulfanyl]-4,6-dimethylnicotinonitrile444081-07-6C15H12Cl2N2S
- 4,6-Dimethyl-2-[(2-nitrophenyl)methylsulfanyl]pyridine-3-carbonitrile213481-47-1C15H13N3O2S
- 6-(Difluoromethyl)-2-[(5-formyl-2-methoxybenzyl)thio]-4-methylnicotinonitrile492428-96-3C17H14F2N2O2S
- 2-[(4-Chlorophenyl)methylsulfanyl]-4-methyl-6-(trifluoromethyl)pyridine-3-carbonitrile514816-28-5C15H10ClF3N2S
- 2-[(3-Bromophenyl)methylsulfanyl]-6-methylpyridine-3-carbonitrile445383-64-2C14H11BrN2S
- 2-[(4-Fluorobenzyl)thio]nicotinic acid460736-49-6C13H10FNO2S
- 2-{[(2-Fluorophenyl)methyl]sulfanyl}pyridine-3-carboxylic acid460736-50-9C13H10FNO2S
- 2-[(2-Chloro-6-nitrobenzyl)sulfanyl]pyridine693240-96-9C12H9ClN2O2S
- 1-[2,4,6-Trimethyl-3-(pyridin-2-ylsulfanylmethyl)phenyl]ethanone693255-28-6C17H19NOS
- 2-[(2-Methoxy-5-nitrophenyl)methylsulfanyl]pyridine693256-19-8C13H12N2O3S
- Methyl 6-(benzylsulfanyl)nicotinate353279-11-5C14H13NO2S
- 6-(Benzylsulfanyl)nicotinic acid353281-45-5C13H11NO2S
- Methyl 2-(benzylthio)nicotinate117569-75-2C14H13NO2S
- 4-{[(3-Cyano-4,6-dimethylpyridin-2-yl)sulfanyl]methyl}benzoic acid371225-75-1C16H14N2O2S
- 2-[(4-Methoxyphenyl)methylsulfanyl]-4,6-dimethylpyridine-3-carbonitrile444080-24-4C16H16N2OS
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals