Murcko scaffold
Ring system with 4 rings and 23 atoms
23 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 23
- With full pages
- 3
Scaffold SMILES
O=c1c2c(ccn1CC1CCCO1)OC=CC2c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 23 of 23 chemicals
![Methyl 2-amino-7-methyl-5-oxo-4-phenyl-6-(tetrahydrofuran-2-ylmethyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C22H24N2O5, CAS 758704-43-7](/s/INBWTBIGTMJKEJ-UHFFFAOYSA-N.svg)
Methyl 2-amino-7-methyl-5-oxo-4-phenyl-6-(tetrahydrofuran-2-ylmethyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 758704-43-7C22H24N2O5
![Methyl 2-amino-4-(2-methoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C23H26N2O6, CAS 758704-47-1](/s/DCBSQNRTTIRNJD-UHFFFAOYSA-N.svg)
Methyl 2-amino-4-(2-methoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 758704-47-1C23H26N2O6
![Methyl 2-amino-4-(4-chlorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C22H23ClN2O5, CAS 758704-44-8](/s/UJHXXLFVTXHFBH-UHFFFAOYSA-N.svg)
Methyl 2-amino-4-(4-chlorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 758704-44-8C22H23ClN2O5
![2-Amino-4-(3-bromophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H20BrN3O3, CAS 638139-20-5](/s/QEPALQMQYXDRBB-UHFFFAOYSA-N.svg)
2-Amino-4-(3-bromophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-20-5C21H20BrN3O3
![2-Amino-4-(2-methoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C22H23N3O4, CAS 758701-84-7](/s/QVSCHRZXAANOFC-UHFFFAOYSA-N.svg)
2-Amino-4-(2-methoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-84-7C22H23N3O4
![2-Amino-4-(2-bromophenyl)-7-methyl-5-oxo-6-(tetrahydrofuran-2-ylmethyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H20BrN3O3, CAS 638139-22-7](/s/BBWGRPHRGLMPOO-UHFFFAOYSA-N.svg)
2-Amino-4-(2-bromophenyl)-7-methyl-5-oxo-6-(tetrahydrofuran-2-ylmethyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-22-7C21H20BrN3O3
![2-Amino-4-(3,4-diethoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C25H29N3O5, CAS 758701-88-1](/s/YOIMMRJZOSHXDY-UHFFFAOYSA-N.svg)
2-Amino-4-(3,4-diethoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-88-1C25H29N3O5
![2-Amino-7-methyl-4-[4-(methylsulfanyl)phenyl]-5-oxo-6-(tetrahydrofuran-2-ylmethyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C22H23N3O3S, CAS 638139-40-9](/s/WBKWAYZGBGAUBX-UHFFFAOYSA-N.svg)
2-Amino-7-methyl-4-[4-(methylsulfanyl)phenyl]-5-oxo-6-(tetrahydrofuran-2-ylmethyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-40-9C22H23N3O3S
![Methyl 4-[2-amino-3-cyano-7-methyl-5-oxo-6-(oxolan-2-ylmethyl)-4H-pyrano[3,2-c]pyridin-4-yl]benzoate chemical structure, C23H23N3O5, CAS 758700-62-8](/s/TUUIMWMGGCTFLH-UHFFFAOYSA-N.svg)
Methyl 4-[2-amino-3-cyano-7-methyl-5-oxo-6-(oxolan-2-ylmethyl)-4H-pyrano[3,2-c]pyridin-4-yl]benzoate
CAS 758700-62-8C23H23N3O5
![2-Amino-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-4-(3,4,5-trimethoxyphenyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C24H27N3O6, CAS 758702-61-3](/s/NYGHNINNVIGASO-UHFFFAOYSA-N.svg)
2-Amino-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-4-(3,4,5-trimethoxyphenyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758702-61-3C24H27N3O6
![2-Amino-4-(4-bromophenyl)-7-methyl-5-oxo-6-(tetrahydrofuran-2-ylmethyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H20BrN3O3, CAS 638139-24-9](/s/VXRMVHSBGZPKEW-UHFFFAOYSA-N.svg)
2-Amino-4-(4-bromophenyl)-7-methyl-5-oxo-6-(tetrahydrofuran-2-ylmethyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-24-9C21H20BrN3O3
![2-Amino-4-(4-ethoxy-3-methoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C24H27N3O5, CAS 638139-30-7](/s/FKCFWYNHXGOBNA-UHFFFAOYSA-N.svg)
2-Amino-4-(4-ethoxy-3-methoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-30-7C24H27N3O5
![2-Amino-4-(3-methoxyphenyl)-7-methyl-5-oxo-6-(oxolan-2-ylmethyl)-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C22H23N3O4, CAS 612802-28-5](/s/FTIQCCNOWCXKQZ-UHFFFAOYSA-N.svg)
2-Amino-4-(3-methoxyphenyl)-7-methyl-5-oxo-6-(oxolan-2-ylmethyl)-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 612802-28-5C22H23N3O4
![2-Amino-4-(3-fluorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H20FN3O3, CAS 638139-14-7](/s/ZYLUYHNECDPIQX-UHFFFAOYSA-N.svg)
2-Amino-4-(3-fluorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-14-7C21H20FN3O3
![2-Amino-4-(2-fluorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H20FN3O3, CAS 638139-18-1](/s/SPHCTPLOWQTOKR-UHFFFAOYSA-N.svg)
2-Amino-4-(2-fluorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-18-1C21H20FN3O3
![Methyl 2-amino-4-(2-chlorophenyl)-7-methyl-5-oxo-6-(oxolan-2-ylmethyl)-4H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C22H23ClN2O5, CAS 758704-48-2](/s/KADHZCPRMDDKGI-UHFFFAOYSA-N.svg)
Methyl 2-amino-4-(2-chlorophenyl)-7-methyl-5-oxo-6-(oxolan-2-ylmethyl)-4H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 758704-48-2C22H23ClN2O5
![2-Amino-4-(3,4-dimethoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C23H25N3O5, CAS 612802-29-6](/s/NXWOKGMJJYVALM-UHFFFAOYSA-N.svg)
2-Amino-4-(3,4-dimethoxyphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 612802-29-6C23H25N3O5
![2-Amino-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-4-(2,3,4-trimethoxyphenyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C24H27N3O6, CAS 712295-85-7](/s/PRZBPXKBCNLXKV-UHFFFAOYSA-N.svg)
2-Amino-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-4-(2,3,4-trimethoxyphenyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 712295-85-7C24H27N3O6
![2-Amino-4-(4-isopropylphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C24H27N3O3, CAS 638139-38-5](/s/SBNDMDZYCGAFQT-UHFFFAOYSA-N.svg)
2-Amino-4-(4-isopropylphenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-38-5C24H27N3O3
![2-Amino-4-(4-fluorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H20FN3O3, CAS 638139-16-9](/s/GBURLUKJKGSRCD-UHFFFAOYSA-N.svg)
2-Amino-4-(4-fluorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 638139-16-9C21H20FN3O3
![2-Amino-4-(4-chlorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H20ClN3O3, CAS 712295-88-0](/s/XWLZRDCUAMXCOP-UHFFFAOYSA-N.svg)
2-Amino-4-(4-chlorophenyl)-7-methyl-5-oxo-6-((tetrahydrofuran-2-yl)methyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 712295-88-0C21H20ClN3O3
![Methyl 2-amino-4-(4-methoxyphenyl)-7-methyl-5-oxo-6-[(oxolan-2-yl)methyl]-4H,5H,6H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C23H26N2O6, CAS 883489-77-8](/s/RNAMSZDQJHRUNK-UHFFFAOYSA-N.svg)
Methyl 2-amino-4-(4-methoxyphenyl)-7-methyl-5-oxo-6-[(oxolan-2-yl)methyl]-4H,5H,6H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 883489-77-8C23H26N2O6
![Methyl 2-amino-4-(3,4-dimethoxyphenyl)-7-methyl-5-oxo-6-[(oxolan-2-yl)methyl]-4H,5H,6H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C24H28N2O7, CAS 883489-86-9](/s/JNOQLXWXVVPHRQ-UHFFFAOYSA-N.svg)
Methyl 2-amino-4-(3,4-dimethoxyphenyl)-7-methyl-5-oxo-6-[(oxolan-2-yl)methyl]-4H,5H,6H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 883489-86-9C24H28N2O7
Related scaffolds
Same ring framework with different atoms or bond orders
