Murcko scaffold
Ring system with 4 rings and 23 atoms
14 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 14
- With full pages
- 1
Scaffold SMILES
O=c1c2c(ccn1Cc1ccco1)OC=CC2c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 14 of 14 chemicals
![2-Amino-4-(3-chlorophenyl)-6-(2-furanylmethyl)-7-methyl-5-oxo-4H-pyrano[3,2-c]pyridine-3-carboxylic acid methyl ester chemical structure, C22H19ClN2O5, CAS 758704-33-5](/s/LEZQTDNNCYFIBU-UHFFFAOYSA-N.svg)
2-Amino-4-(3-chlorophenyl)-6-(2-furanylmethyl)-7-methyl-5-oxo-4H-pyrano[3,2-c]pyridine-3-carboxylic acid methyl ester
CAS 758704-33-5C22H19ClN2O5
![2-Amino-4-(4-chlorophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H16ClN3O3, CAS 758701-63-2](/s/REYALCMPGBJDER-UHFFFAOYSA-N.svg)
2-Amino-4-(4-chlorophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-63-2C21H16ClN3O3
![2-Amino-4-(3,4-diethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C25H25N3O5, CAS 758701-68-7](/s/GGJGRDILXCEYPJ-UHFFFAOYSA-N.svg)
2-Amino-4-(3,4-diethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-68-7C25H25N3O5
![2-Amino-4-(3,4-dimethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C23H21N3O5, CAS 710317-07-0](/s/ONDDNEWRNICPLR-UHFFFAOYSA-N.svg)
2-Amino-4-(3,4-dimethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 710317-07-0C23H21N3O5
![2-Amino-4-(4-bromophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C21H16BrN3O3, CAS 758701-65-4](/s/LEQWXOPMINGMSN-UHFFFAOYSA-N.svg)
2-Amino-4-(4-bromophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-65-4C21H16BrN3O3
![2-Amino-4-(2,5-dimethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C23H21N3O5, CAS 758701-78-9](/s/BVMWRCXWSHOJMV-UHFFFAOYSA-N.svg)
2-Amino-4-(2,5-dimethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-78-9C23H21N3O5
![2-Amino-6-(furan-2-ylmethyl)-4-(2-methoxyphenyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C22H19N3O4, CAS 758701-70-1](/s/QSSCPLQIEDVISQ-UHFFFAOYSA-N.svg)
2-Amino-6-(furan-2-ylmethyl)-4-(2-methoxyphenyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-70-1C22H19N3O4
![Methyl 2-amino-4-(2-chlorophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C22H19ClN2O5, CAS 758704-41-5](/s/IJNPHAALZSOWAG-UHFFFAOYSA-N.svg)
Methyl 2-amino-4-(2-chlorophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 758704-41-5C22H19ClN2O5
![Methyl 2-amino-4-(3,4-dichlorophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C22H18Cl2N2O5, CAS 758704-35-7](/s/HGZKZFKFXWNILG-UHFFFAOYSA-N.svg)
Methyl 2-amino-4-(3,4-dichlorophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 758704-35-7C22H18Cl2N2O5
![Methyl 2-amino-6-(furan-2-ylmethyl)-4-(3-methoxyphenyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C23H22N2O6, CAS 758703-53-6](/s/QAGSTWWQZBECMR-UHFFFAOYSA-N.svg)
Methyl 2-amino-6-(furan-2-ylmethyl)-4-(3-methoxyphenyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 758703-53-6C23H22N2O6
![2-Amino-4-(2,4-dimethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C23H21N3O5, CAS 758701-72-3](/s/YYEALYQFOFSZQQ-UHFFFAOYSA-N.svg)
2-Amino-4-(2,4-dimethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-72-3C23H21N3O5
![Methyl 2-amino-4-(4-chlorophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate chemical structure, C22H19ClN2O5, CAS 758704-37-9](/s/VCEGYQIPZGVMEO-UHFFFAOYSA-N.svg)
Methyl 2-amino-4-(4-chlorophenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carboxylate
CAS 758704-37-9C22H19ClN2O5
![2-Amino-4-(2,3-dimethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C23H21N3O5, CAS 758701-74-5](/s/LMCCWXOGMZDZAY-UHFFFAOYSA-N.svg)
2-Amino-4-(2,3-dimethoxyphenyl)-6-(furan-2-ylmethyl)-7-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-74-5C23H21N3O5
![2-Amino-6-(furan-2-ylmethyl)-7-methyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile chemical structure, C24H23N3O6, CAS 758701-67-6](/s/DJSVZCNKBRWAFK-UHFFFAOYSA-N.svg)
2-Amino-6-(furan-2-ylmethyl)-7-methyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-5,6-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile
CAS 758701-67-6C24H23N3O6
Related scaffolds
Same ring framework with different atoms or bond orders
