CompoundList
Sign in
Murcko scaffold

N-Phenyl-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide scaffold

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
24
With full pages
5
Scaffold SMILES

O=C(Nc1ccccc1)C1CCCN1S(=O)(=O)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide page
Murcko scaffold O=C(Nc1ccccc1)C1CCCN1S(=O)(=O)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

1-(Thiophen-2-ylsulfonyl)-N-[3-(trifluoromethyl)phenyl]prolinamide chemical structure, C16H15F3N2O3S2, CAS 1025686-92-3
1-(Thiophen-2-ylsulfonyl)-N-[3-(trifluoromethyl)phenyl]prolinamide
CAS 1025686-92-3C16H15F3N2O3S2
N-Phenyl-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide chemical structure, C15H16N2O3S2, CAS 1008668-15-2
N-Phenyl-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide
CAS 1008668-15-2C15H16N2O3S2
N-(4-Chlorophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide chemical structure, C15H15ClN2O3S2, CAS 1008935-26-9
N-(4-Chlorophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide
CAS 1008935-26-9C15H15ClN2O3S2
N-(3,5-Dichlorophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide chemical structure, C15H14Cl2N2O3S2, CAS 1009269-25-3
N-(3,5-Dichlorophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide
CAS 1009269-25-3C15H14Cl2N2O3S2
N-(4-Acetylphenyl)-1-(2-thienylsulfonyl)pyrrolidine-2-carboxamide chemical structure, C17H18N2O4S2, CAS 1008668-73-2
N-(4-Acetylphenyl)-1-(2-thienylsulfonyl)pyrrolidine-2-carboxamide
CAS 1008668-73-2C17H18N2O4S2
N-(3-Acetylphenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide chemical structure, C17H18N2O4S2, CAS 1008957-07-0
N-(3-Acetylphenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide
CAS 1008957-07-0C17H18N2O4S2
N-(4-Methoxy-2-nitrophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide chemical structure, C16H17N3O6S2, CAS 1105638-75-2
N-(4-Methoxy-2-nitrophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide
CAS 1105638-75-2C16H17N3O6S2
N-(4-Fluorophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide chemical structure, C15H15FN2O3S2, CAS 1008957-08-1
N-(4-Fluorophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide
CAS 1008957-08-1C15H15FN2O3S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2-cyanophenyl)pyrrolidine-2-carboxamide chemical structure, C16H14ClN3O3S2, CAS 1009266-57-2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2-cyanophenyl)pyrrolidine-2-carboxamide
CAS 1009266-57-2C16H14ClN3O3S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(3,5-dichlorophenyl)pyrrolidine-2-carboxamide chemical structure, C15H13Cl3N2O3S2, CAS 1050211-02-3
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(3,5-dichlorophenyl)pyrrolidine-2-carboxamide
CAS 1050211-02-3C15H13Cl3N2O3S2
N-(4-Acetylphenyl)-1-((5-chlorothiophen-2-yl)sulfonyl)pyrrolidine-2-carboxamide chemical structure, C17H17ClN2O4S2, CAS 1008285-90-2
N-(4-Acetylphenyl)-1-((5-chlorothiophen-2-yl)sulfonyl)pyrrolidine-2-carboxamide
CAS 1008285-90-2C17H17ClN2O4S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(3,5-dimethylphenyl)pyrrolidine-2-carboxamide chemical structure, C17H19ClN2O3S2, CAS 1009576-21-9
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(3,5-dimethylphenyl)pyrrolidine-2-carboxamide
CAS 1009576-21-9C17H19ClN2O3S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(4-(methylthio)phenyl)pyrrolidine-2-carboxamide chemical structure, C16H17ClN2O3S3, CAS 1050212-45-7
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(4-(methylthio)phenyl)pyrrolidine-2-carboxamide
CAS 1050212-45-7C16H17ClN2O3S3
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(4-(methylsulfonyl)phenyl)pyrrolidine-2-carboxamide chemical structure, C16H17ClN2O5S3, CAS 1050212-47-9
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(4-(methylsulfonyl)phenyl)pyrrolidine-2-carboxamide
CAS 1050212-47-9C16H17ClN2O5S3
N-(2-Methoxy-5-nitrophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide chemical structure, C16H17N3O6S2, CAS 1103509-43-8
N-(2-Methoxy-5-nitrophenyl)-1-(thiophen-2-ylsulfonyl)pyrrolidine-2-carboxamide
CAS 1103509-43-8C16H17N3O6S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(4-nitrophenyl)pyrrolidine-2-carboxamide chemical structure, C15H14ClN3O5S2, CAS 1103935-34-7
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(4-nitrophenyl)pyrrolidine-2-carboxamide
CAS 1103935-34-7C15H14ClN3O5S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(3-nitrophenyl)pyrrolidine-2-carboxamide chemical structure, C15H14ClN3O5S2, CAS 1093770-08-1
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(3-nitrophenyl)pyrrolidine-2-carboxamide
CAS 1093770-08-1C15H14ClN3O5S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2-methoxy-5-nitrophenyl)pyrrolidine-2-carboxamide chemical structure, C16H16ClN3O6S2, CAS 1105547-90-7
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2-methoxy-5-nitrophenyl)pyrrolidine-2-carboxamide
CAS 1105547-90-7C16H16ClN3O6S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2-methoxy-4-nitrophenyl)pyrrolidine-2-carboxamide chemical structure, C16H16ClN3O6S2, CAS 1105638-84-3
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2-methoxy-4-nitrophenyl)pyrrolidine-2-carboxamide
CAS 1105638-84-3C16H16ClN3O6S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(4-methoxy-2-nitrophenyl)pyrrolidine-2-carboxamide chemical structure, C16H16ClN3O6S2, CAS 1105638-89-8
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(4-methoxy-2-nitrophenyl)pyrrolidine-2-carboxamide
CAS 1105638-89-8C16H16ClN3O6S2
N-(4-Bromophenyl)-1-((5-chlorothiophen-2-yl)sulfonyl)pyrrolidine-2-carboxamide chemical structure, C15H14BrClN2O3S2, CAS 1101179-05-8
N-(4-Bromophenyl)-1-((5-chlorothiophen-2-yl)sulfonyl)pyrrolidine-2-carboxamide
CAS 1101179-05-8C15H14BrClN2O3S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2,5-dichlorophenyl)pyrrolidine-2-carboxamide chemical structure, C15H13Cl3N2O3S2, CAS 1097833-77-6
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2,5-dichlorophenyl)pyrrolidine-2-carboxamide
CAS 1097833-77-6C15H13Cl3N2O3S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2,3-dichlorophenyl)pyrrolidine-2-carboxamide chemical structure, C15H13Cl3N2O3S2, CAS 1101179-10-5
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2,3-dichlorophenyl)pyrrolidine-2-carboxamide
CAS 1101179-10-5C15H13Cl3N2O3S2
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2-(methylthio)phenyl)pyrrolidine-2-carboxamide chemical structure, C16H17ClN2O3S3, CAS 1101206-40-9
1-((5-Chlorothiophen-2-yl)sulfonyl)-N-(2-(methylthio)phenyl)pyrrolidine-2-carboxamide
CAS 1101206-40-9C16H17ClN2O3S3