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Murcko scaffold

Ring system with 3 rings and 20 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
15
With full pages
1
Scaffold SMILES

O=C(C1CCCC1)N1CCN=C1SCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C1CCCC1)N1CCN=C1SCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

[2-[(3-Chlorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-cyclopentylmethanone chemical structure, C16H19ClN2OS, CAS 851807-98-2
[2-[(3-Chlorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-cyclopentylmethanone
CAS 851807-98-2C16H19ClN2OS
Cyclopentyl(2-((3-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C17H19F3N2OS, CAS 851805-56-6
Cyclopentyl(2-((3-(trifluoromethyl)benzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851805-56-6C17H19F3N2OS
Cyclopentyl-[2-[(4-nitrophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C16H19N3O3S, CAS 851802-08-9
Cyclopentyl-[2-[(4-nitrophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851802-08-9C16H19N3O3S
[2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-cyclopentylmethanone chemical structure, C16H18ClFN2OS, CAS 851802-67-0
[2-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-cyclopentylmethanone
CAS 851802-67-0C16H18ClFN2OS
Cyclopentyl(2-((3-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C16H19FN2OS, CAS 851864-71-6
Cyclopentyl(2-((3-fluorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851864-71-6C16H19FN2OS
Cyclopentyl(2-((2,5-dimethylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C18H24N2OS, CAS 851804-25-6
Cyclopentyl(2-((2,5-dimethylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851804-25-6C18H24N2OS
Cyclopentyl-[2-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C17H19F3N2OS, CAS 851805-96-4
Cyclopentyl-[2-[[4-(trifluoromethyl)phenyl]methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851805-96-4C17H19F3N2OS
[2-[(4-Bromophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-cyclopentylmethanone chemical structure, C16H19BrN2OS, CAS 851800-37-8
[2-[(4-Bromophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]-cyclopentylmethanone
CAS 851800-37-8C16H19BrN2OS
Cyclopentyl(2-((3-nitrobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C16H19N3O3S, CAS 851808-43-0
Cyclopentyl(2-((3-nitrobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851808-43-0C16H19N3O3S
(2-((4-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopentyl)methanone chemical structure, C16H19ClN2OS, CAS 851801-48-4
(2-((4-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopentyl)methanone
CAS 851801-48-4C16H19ClN2OS
(2-((2-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopentyl)methanone chemical structure, C16H19ClN2OS, CAS 851803-82-2
(2-((2-Chlorobenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)(cyclopentyl)methanone
CAS 851803-82-2C16H19ClN2OS
Cyclopentyl-[2-[(2-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C16H19FN2OS, CAS 851806-66-1
Cyclopentyl-[2-[(2-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851806-66-1C16H19FN2OS
Cyclopentyl-[2-[(4-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone chemical structure, C16H19FN2OS, CAS 851865-50-4
Cyclopentyl-[2-[(4-fluorophenyl)methylsulfanyl]-4,5-dihydroimidazol-1-yl]methanone
CAS 851865-50-4C16H19FN2OS
Cyclopentyl(2-((4-methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C17H22N2OS, CAS 851804-79-0
Cyclopentyl(2-((4-methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851804-79-0C17H22N2OS
Cyclopentyl(2-((3-methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone chemical structure, C17H22N2OS, CAS 851803-14-0
Cyclopentyl(2-((3-methylbenzyl)thio)-4,5-dihydro-1H-imidazol-1-yl)methanone
CAS 851803-14-0C17H22N2OS