Murcko scaffold
Ring system with 2 rings and 9 atoms
18 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 18
- With full pages
- 4
Scaffold SMILES
c1cc2ccocc-2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 18 of 18 chemicals
Homobaldrinal
CAS 67910-07-0C15H16O4
Cyclopenta(c)pyran-7-carboxaldehyde, 4-(hydroxymethyl)-
CAS 71013-42-8C10H8O3
Baldrinal
CAS 18234-46-3C12H10O4
Norviburtinal
CAS 85051-41-8C9H6O2
Viburtinal
CAS 63661-79-0C10H8O2
Methyl 7-methylcyclopenta(c)pyran-4-carboxylate
CAS 63785-74-0C11H10O3
Cyclopenta(c)pyran-7-carboxaldehyde, 4-(ethoxymethyl)-
CAS 97856-20-7C12H12O3
Cerbinal
CAS 65597-42-4C11H8O4
![6-Benzo[b]furanethanol chemical structure, C10H10O2, CAS 169785-09-5](/s/UBINRCSQAXPYMT-UHFFFAOYSA-N.svg)
6-Benzo[b]furanethanol
CAS 169785-09-5C10H10O2
![7-Formylcyclopenta[c]pyran-4-carboxylic acid chemical structure, C10H6O4, CAS 65597-43-5](/s/SAUXEYGZKWTNEU-UHFFFAOYSA-N.svg)
7-Formylcyclopenta[c]pyran-4-carboxylic acid
CAS 65597-43-5C10H6O4
![(4-Methoxycyclopenta[c]pyran-1-yl)methanol chemical structure, C10H10O3, CAS 499235-49-3](/s/UWCSJQJCGAOMAR-UHFFFAOYSA-N.svg)
(4-Methoxycyclopenta[c]pyran-1-yl)methanol
CAS 499235-49-3C10H10O3
Cerberic acid
CAS 65597-44-6C11H8O5
![(6-Methylcyclopenta[c]pyran-5-yl)hydrazine chemical structure, C9H10N2O, CAS 1823891-93-5](/s/HPHJDMZURPVOQS-UHFFFAOYSA-N.svg)
(6-Methylcyclopenta[c]pyran-5-yl)hydrazine
CAS 1823891-93-5C9H10N2O
![2-Cyclopenta[c]pyran-1-ylacetohydrazide chemical structure, C10H10N2O2, CAS 943541-29-5](/s/AWQFQAWBLFFGNL-UHFFFAOYSA-N.svg)
2-Cyclopenta[c]pyran-1-ylacetohydrazide
CAS 943541-29-5C10H10N2O2
4-Hydroxy-5-benzofuranacetic acid
CAS 1524754-10-6C10H8O4
7-Bromo-3-(trifluoromethyl)-5-benzofuranmethanol
CAS 2378268-77-8C10H6BrF3O2
Ethyl 7-bromo-5-benzofuranacetate
CAS 1260774-41-1C12H11BrO3
3-Bromo-5-benzofuranmethanol
CAS 1781640-58-1C9H7BrO2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
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c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals