CompoundList
Sign in
Murcko scaffold

5H,6H,7H-Cyclopenta(d)pyrimidine-2,4-diol scaffold

13 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
13
With full pages
3
Scaffold SMILES

O=c1[nH]c2c(c(=O)[nH]1)CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5H,6H,7H-Cyclopenta(d)pyrimidine-2,4-diol page
Murcko scaffold O=c1[nH]c2c(c(=O)[nH]1)CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

1H-Cyclopentapyrimidine-2,4(3H,5H)-dione, 6,7-dihydro-1,3-dimethyl- chemical structure, C9H12N2O2, CAS 49786-32-5
1H-Cyclopentapyrimidine-2,4(3H,5H)-dione, 6,7-dihydro-1,3-dimethyl-
CAS 49786-32-5C9H12N2O2
1H-Cyclopentapyrimidine-1-acetamide, 2,3,4,5,6,7-hexahydro-2,4-dioxo-N,N,3-trimethyl- chemical structure, C12H17N3O3, CAS 49786-46-1
1H-Cyclopentapyrimidine-1-acetamide, 2,3,4,5,6,7-hexahydro-2,4-dioxo-N,N,3-trimethyl-
CAS 49786-46-1C12H17N3O3
1H-Cyclopentapyrimidine-2,4(3H,5H)-dione, 6,7-dihydro-1-(2-(diethylamino)ethyl)-3-methyl-, monohydrochloride chemical structure, C14H24ClN3O2, CAS 49786-55-2
1H-Cyclopentapyrimidine-2,4(3H,5H)-dione, 6,7-dihydro-1-(2-(diethylamino)ethyl)-3-methyl-, monohydrochloride
CAS 49786-55-2C14H24ClN3O2
1H-Cyclopentapyrimidine-2,4(3H,5H)-dione, 6,7-dihydro-3-allyl-1-methyl- chemical structure, C11H14N2O2, CAS 49786-62-1
1H-Cyclopentapyrimidine-2,4(3H,5H)-dione, 6,7-dihydro-3-allyl-1-methyl-
CAS 49786-62-1C11H14N2O2
5H,6H,7H-Cyclopenta(d)pyrimidine-2,4-diol chemical structure, C7H8N2O2, CAS 5466-00-2
5H,6H,7H-Cyclopenta(d)pyrimidine-2,4-diol
CAS 5466-00-2C7H8N2O2
(S)-2-Amino-3-(1,3,5,7-pentahydro-2,4-dioxo-cyclopenta(E)pyrimidin-1-yl) proionic acid chemical structure, C10H13N3O4, CAS 389888-02-2
(S)-2-Amino-3-(1,3,5,7-pentahydro-2,4-dioxo-cyclopenta(E)pyrimidin-1-yl) proionic acid
CAS 389888-02-2C10H13N3O4
3-Hexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione chemical structure, C13H20N2O2, CAS 301169-48-2
3-Hexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione
CAS 301169-48-2C13H20N2O2
6,6-Dimethyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione chemical structure, C9H12N2O2, CAS 67566-51-2
6,6-Dimethyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione
CAS 67566-51-2C9H12N2O2
1-Methyl-1H,2H,3H,4H,5H,6H,7H-cyclopenta[d]pyrimidine-2,4-dione chemical structure, C8H10N2O2, CAS 21582-84-3
1-Methyl-1H,2H,3H,4H,5H,6H,7H-cyclopenta[d]pyrimidine-2,4-dione
CAS 21582-84-3C8H10N2O2
5-Methyl-1H,2H,3H,4H,5H,6H,7H-cyclopenta[d]pyrimidine-2,4-dione chemical structure, C8H10N2O2, CAS 1375474-65-9
5-Methyl-1H,2H,3H,4H,5H,6H,7H-cyclopenta[d]pyrimidine-2,4-dione
CAS 1375474-65-9C8H10N2O2
7,7-Dimethyl-1H,2H,3H,4H,5H,6H,7H-cyclopenta[d]pyrimidine-2,4-dione chemical structure, C9H12N2O2, CAS 1513036-82-2
7,7-Dimethyl-1H,2H,3H,4H,5H,6H,7H-cyclopenta[d]pyrimidine-2,4-dione
CAS 1513036-82-2C9H12N2O2
7-Bromo-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione chemical structure, C7H7BrN2O2, CAS 1447671-23-9
7-Bromo-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione
CAS 1447671-23-9C7H7BrN2O2
7,7-Difluoro-5,6-dihydro-1H-cyclopenta[d]pyrimidine-2,4-dione chemical structure, C7H6F2N2O2, CAS 2512235-04-8
7,7-Difluoro-5,6-dihydro-1H-cyclopenta[d]pyrimidine-2,4-dione
CAS 2512235-04-8C7H6F2N2O2