Murcko scaffold
Ring system with 5 rings and 28 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 28
- Chemicals
- 6
- With full pages
- 1
Scaffold SMILES
c1ccc(NCc2nc(-c3ccc4ncnn4c3)c(-c3ccccn3)[nH]2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1ccc(NCc2nc(-c3ccc4ncnn4c3)c(-c3ccccn3)[nH]2)cc1](/scaffold/VBRFTSZZAOIPKQ-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
Vactosertib
CAS 1352608-82-2C22H18FN7
Vactosertib hydrochloride
CAS 1352610-25-3C22H19ClFN7
![N-(3-Fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine chemical structure, C22H18FN7, CAS 1352608-83-3](/s/COZUKVUBSCQZGM-UHFFFAOYSA-N.svg)
N-(3-Fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine
CAS 1352608-83-3C22H18FN7
![N-((4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline chemical structure, C22H18BrN7, CAS 1352608-94-6](/s/SJOMJTKWXZEYKX-UHFFFAOYSA-N.svg)
N-((4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
CAS 1352608-94-6C22H18BrN7
![3-[[5-(6-Methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile chemical structure, C23H18N8, CAS 1352609-28-9](/s/KEADGKSQIBFYEE-UHFFFAOYSA-N.svg)
3-[[5-(6-Methyl-2-pyridinyl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methylamino]benzonitrile
CAS 1352609-28-9C23H18N8
![N-((4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline hydrochloride chemical structure, C22H19BrClN7, CAS 1352610-29-7](/s/LKAWVMGPKHOLPR-UHFFFAOYSA-N.svg)
N-((4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline hydrochloride
CAS 1352610-29-7C22H19BrClN7