CompoundList
Sign in
Murcko scaffold

10-Oxa-4-azatricyclo(5.2.1.02,6)decane-3,5-dione scaffold

43 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
43
With full pages
7
Scaffold SMILES

O=C1NC(=O)C2C3CCC(O3)C12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 10-Oxa-4-azatricyclo(5.2.1.02,6)decane-3,5-dione page
Murcko scaffold O=C1NC(=O)C2C3CCC(O3)C12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

2-(2-Hydroxypropyl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione chemical structure, C11H15NO4, CAS 20711-66-4
2-(2-Hydroxypropyl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS 20711-66-4C11H15NO4
Cantharidin imide chemical structure, C10H13NO3, CAS 76970-77-9
Cantharidin imide
CAS 76970-77-9C10H13NO3
Methylcantharidimide chemical structure, C11H15NO3, CAS 76970-78-0
Methylcantharidimide
CAS 76970-78-0C11H15NO3
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, hexahydro-2-ethyl-, (3aR-(3a-alpha,4-beta,7-beta,7a-alpha))- chemical structure, C10H13NO3, CAS 70223-91-5
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, hexahydro-2-ethyl-, (3aR-(3a-alpha,4-beta,7-beta,7a-alpha))-
CAS 70223-91-5C10H13NO3
N-Hydroxycantharidinimide chemical structure, C10H13NO4, CAS 76057-97-1
N-Hydroxycantharidinimide
CAS 76057-97-1C10H13NO4
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, hexahydro-3a,7a-dimethyl-2-(2-propenyl)-, (3aalpha,4beta,7beta,7aalpha)- chemical structure, C13H17NO3, CAS 76970-79-1
4,7-Epoxy-1H-isoindole-1,3(2H)-dione, hexahydro-3a,7a-dimethyl-2-(2-propenyl)-, (3aalpha,4beta,7beta,7aalpha)-
CAS 76970-79-1C13H17NO3
rel-(3aR,4S,7R,7aS)-Hexahydro-4,7-epoxy-1H-isoindole-1,3(2H)-dione chemical structure, C8H9NO3, CAS 28871-91-2
rel-(3aR,4S,7R,7aS)-Hexahydro-4,7-epoxy-1H-isoindole-1,3(2H)-dione
CAS 28871-91-2C8H9NO3
10-Oxa-4-azatricyclo(5.2.1.02,6)decane-3,5-dione chemical structure, C8H9NO3, CAS 6253-24-3
10-Oxa-4-azatricyclo(5.2.1.02,6)decane-3,5-dione
CAS 6253-24-3C8H9NO3
4-Methylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione chemical structure, C9H11NO3, CAS 6624-08-4
4-Methylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS 6624-08-4C9H11NO3
4,7-Epoxy-2-methyl-2,3,3A,4,5,6,7,7A-octahydro-1H-isoindole-1,3-dione chemical structure, C9H11NO3, CAS 7741-81-3
4,7-Epoxy-2-methyl-2,3,3A,4,5,6,7,7A-octahydro-1H-isoindole-1,3-dione
CAS 7741-81-3C9H11NO3
2-(Dimethylamino)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione chemical structure, C10H14N2O3, CAS 91761-30-7
2-(Dimethylamino)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS 91761-30-7C10H14N2O3
2-Pentylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione chemical structure, C13H19NO3, CAS 7247-81-6
2-Pentylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS 7247-81-6C13H19NO3
2-Octylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione chemical structure, C16H25NO3, CAS 94461-26-4
2-Octylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS 94461-26-4C16H25NO3
7-Oxabicyclo(2.2.1)heptane-2,3-dicarboximide, N-(dimethylthiocarbamoyl)- chemical structure, C11H14N2O3S, CAS 73806-12-9
7-Oxabicyclo(2.2.1)heptane-2,3-dicarboximide, N-(dimethylthiocarbamoyl)-
CAS 73806-12-9C11H14N2O3S
2-(2-Hydroxyethyl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione chemical structure, C10H13NO4, CAS 91877-89-3
2-(2-Hydroxyethyl)hexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS 91877-89-3C10H13NO4
2-Butylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione chemical structure, C12H17NO3, CAS 91645-06-6
2-Butylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS 91645-06-6C12H17NO3
2-Propylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione chemical structure, C11H15NO3, CAS 92147-33-6
2-Propylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS 92147-33-6C11H15NO3
(1,3-Dioxooctahydro-2H-4,7-epoxyisoindol-2-yl)methyl acetate chemical structure, C11H13NO5, CAS 73806-13-0
(1,3-Dioxooctahydro-2H-4,7-epoxyisoindol-2-yl)methyl acetate
CAS 73806-13-0C11H13NO5
2-{3,5-Dioxo-10-oxa-4-azatricyclo[5.2.1.0,2,6]decan-4-yl}acetic acid chemical structure, C10H11NO5, CAS 1212310-79-6
2-{3,5-Dioxo-10-oxa-4-azatricyclo[5.2.1.0,2,6]decan-4-yl}acetic acid
CAS 1212310-79-6C10H11NO5
2-(Trichloromethylsulfanyl)-3a,4,5,6,7,7a-hexahydro-4,7-epoxyisoindole-1,3-dione chemical structure, C9H8Cl3NO3S, CAS 2779-48-8
2-(Trichloromethylsulfanyl)-3a,4,5,6,7,7a-hexahydro-4,7-epoxyisoindole-1,3-dione
CAS 2779-48-8C9H8Cl3NO3S
2-(2-(Dimethylamino)ethyl)-4-methylhexahydro-1H-4,7-epoxyisoindole-1,3-dione chemical structure, C13H20N2O3, CAS 6624-10-8
2-(2-(Dimethylamino)ethyl)-4-methylhexahydro-1H-4,7-epoxyisoindole-1,3-dione
CAS 6624-10-8C13H20N2O3
2-(2-(Dimethylamino)ethyl)-3a,7a-dimethylhexahydro-1H-4,7-epoxyisoindole-1,3-dione chemical structure, C14H22N2O3, CAS 6949-25-3
2-(2-(Dimethylamino)ethyl)-3a,7a-dimethylhexahydro-1H-4,7-epoxyisoindole-1,3-dione
CAS 6949-25-3C14H22N2O3
7-Oxabicyclo(2.2.1)heptane-2,3-dicarboximide, N-(4-chloro-2-butynyl)- chemical structure, C12H12ClNO3, CAS 73806-10-7
7-Oxabicyclo(2.2.1)heptane-2,3-dicarboximide, N-(4-chloro-2-butynyl)-
CAS 73806-10-7C12H12ClNO3
N,N-Dimethyl-1,3-dioxooctahydro-2H-4,7-epoxyisoindole-2-sulfonamide chemical structure, C10H14N2O5S, CAS 57105-59-6
N,N-Dimethyl-1,3-dioxooctahydro-2H-4,7-epoxyisoindole-2-sulfonamide
CAS 57105-59-6C10H14N2O5S