CompoundList
Sign in
Murcko scaffold

4-(2-Phenoxyacetyl)piperazin-2-one scaffold

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
17
With full pages
4
Scaffold SMILES

O=C1CN(C(=O)COc2ccccc2)CCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(2-Phenoxyacetyl)piperazin-2-one page
Murcko scaffold O=C1CN(C(=O)COc2ccccc2)CCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

4-(2-Phenoxyacetyl)piperazin-2-one chemical structure, C12H14N2O3, CAS 587850-66-6
4-(2-Phenoxyacetyl)piperazin-2-one
CAS 587850-66-6C12H14N2O3
Methyl {1-[(4-chlorophenoxy)acetyl]-3-oxopiperazin-2-yl}acetate chemical structure, C15H17ClN2O5, CAS 474262-23-2
Methyl {1-[(4-chlorophenoxy)acetyl]-3-oxopiperazin-2-yl}acetate
CAS 474262-23-2C15H17ClN2O5
Ethyl {1-[(4-bromo-2-methylphenoxy)acetyl]-3-oxo-2-piperazinyl}acetate chemical structure, C17H21BrN2O5, CAS 1008061-73-1
Ethyl {1-[(4-bromo-2-methylphenoxy)acetyl]-3-oxo-2-piperazinyl}acetate
CAS 1008061-73-1C17H21BrN2O5
Ethyl 2-[1-[2-(4-tert-butylphenoxy)acetyl]-3-oxopiperazin-2-yl]acetate chemical structure, C20H28N2O5, CAS 1009617-77-9
Ethyl 2-[1-[2-(4-tert-butylphenoxy)acetyl]-3-oxopiperazin-2-yl]acetate
CAS 1009617-77-9C20H28N2O5
Propan-2-yl 2-[1-[2-(4-tert-butylphenoxy)acetyl]-3-oxopiperazin-2-yl]acetate chemical structure, C21H30N2O5, CAS 1008006-51-6
Propan-2-yl 2-[1-[2-(4-tert-butylphenoxy)acetyl]-3-oxopiperazin-2-yl]acetate
CAS 1008006-51-6C21H30N2O5
4-(2-(4-Chlorophenoxy)acetyl)piperazin-2-one chemical structure, C12H13ClN2O3, CAS 923177-66-6
4-(2-(4-Chlorophenoxy)acetyl)piperazin-2-one
CAS 923177-66-6C12H13ClN2O3
4-[2-(4-Chlorophenoxy)acetyl]-3,3-dimethylpiperazin-2-one chemical structure, C14H17ClN2O3, CAS 946363-02-6
4-[2-(4-Chlorophenoxy)acetyl]-3,3-dimethylpiperazin-2-one
CAS 946363-02-6C14H17ClN2O3
4-[2-(2,4-Dichlorophenoxy)acetyl]-3,3-dimethylpiperazin-2-one chemical structure, C14H16Cl2N2O3, CAS 946281-91-0
4-[2-(2,4-Dichlorophenoxy)acetyl]-3,3-dimethylpiperazin-2-one
CAS 946281-91-0C14H16Cl2N2O3
4-(2-(4-Bromophenoxy)acetyl)piperazin-2-one chemical structure, C12H13BrN2O3, CAS 930928-60-2
4-(2-(4-Bromophenoxy)acetyl)piperazin-2-one
CAS 930928-60-2C12H13BrN2O3
4-[2-Oxo-2-(3-oxo-1-piperazinyl)ethoxy]benzonitrile chemical structure, C13H13N3O3, CAS 1016827-32-9
4-[2-Oxo-2-(3-oxo-1-piperazinyl)ethoxy]benzonitrile
CAS 1016827-32-9C13H13N3O3
4-(2-(4-Chlorophenoxy)-2-methylpropanoyl)piperazin-2-one chemical structure, C14H17ClN2O3, CAS 1088198-98-4
4-(2-(4-Chlorophenoxy)-2-methylpropanoyl)piperazin-2-one
CAS 1088198-98-4C14H17ClN2O3
4-(2-(4-Fluorophenoxy)acetyl)piperazin-2-one chemical structure, C12H13FN2O3, CAS 1283002-57-2
4-(2-(4-Fluorophenoxy)acetyl)piperazin-2-one
CAS 1283002-57-2C12H13FN2O3
4-(2-(2,4-Difluorophenoxy)acetyl)piperazin-2-one chemical structure, C12H12F2N2O3, CAS 1241179-36-1
4-(2-(2,4-Difluorophenoxy)acetyl)piperazin-2-one
CAS 1241179-36-1C12H12F2N2O3
4-[2-(4-Chlorophenoxy)acetyl]-3-methylpiperazin-2-one chemical structure, C13H15ClN2O3, CAS 1103647-45-5
4-[2-(4-Chlorophenoxy)acetyl]-3-methylpiperazin-2-one
CAS 1103647-45-5C13H15ClN2O3
4-[2-(2,4-Dichlorophenoxy)acetyl]-3-methylpiperazin-2-one chemical structure, C13H14Cl2N2O3, CAS 1103664-01-2
4-[2-(2,4-Dichlorophenoxy)acetyl]-3-methylpiperazin-2-one
CAS 1103664-01-2C13H14Cl2N2O3
4-(2-(2-Chlorophenoxy)acetyl)piperazin-2-one chemical structure, C12H13ClN2O3, CAS 1240865-81-9
4-(2-(2-Chlorophenoxy)acetyl)piperazin-2-one
CAS 1240865-81-9C12H13ClN2O3
4-[2-(4-Chlorophenoxy)propanoyl]piperazin-2-one chemical structure, C13H15ClN2O3, CAS 1282491-37-5
4-[2-(4-Chlorophenoxy)propanoyl]piperazin-2-one
CAS 1282491-37-5C13H15ClN2O3