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Murcko scaffold

2,3,4,5-Tetrahydro-1,5-benzoxazepin-4-one scaffold

308 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
308
With full pages
8
Scaffold SMILES

O=C1CCOc2ccccc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3,4,5-Tetrahydro-1,5-benzoxazepin-4-one page
Murcko scaffold O=C1CCOc2ccccc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 308 chemicals

3-Chloro-6-methyl-6,7-dihydro-9H-5-oxa-9-azabenzocyclohepten-8-one chemical structure, C10H10ClNO2, CAS 134076-61-2
3-Chloro-6-methyl-6,7-dihydro-9H-5-oxa-9-azabenzocyclohepten-8-one
CAS 134076-61-2C10H10ClNO2
2-Methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-7-carboxylic acid chemical structure, C11H11NO4, CAS 134076-69-0
2-Methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine-7-carboxylic acid
CAS 134076-69-0C11H11NO4
2-Methyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one chemical structure, C10H11NO2, CAS 130781-55-4
2-Methyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one
CAS 130781-55-4C10H11NO2
2-(4-Oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-5-yl)acetic acid chemical structure, C11H11NO4, CAS 863668-08-0
2-(4-Oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-5-yl)acetic acid
CAS 863668-08-0C11H11NO4
2,3,4,5-Tetrahydro-1,5-benzoxazepin-4-one chemical structure, C9H9NO2, CAS 704-48-3
2,3,4,5-Tetrahydro-1,5-benzoxazepin-4-one
CAS 704-48-3C9H9NO2
3-Amino-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one chemical structure, C9H10N2O2, CAS 94590-46-2
3-Amino-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one
CAS 94590-46-2C9H10N2O2
(R)-3-Amino-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one chemical structure, C9H10N2O2, CAS 158892-18-3
(R)-3-Amino-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one
CAS 158892-18-3C9H10N2O2
3-(Trifluoromethyl)-2,3-dihydro-1,5-benzoxazepin-4(5H)-one chemical structure, C10H8F3NO2, CAS 110579-27-6
3-(Trifluoromethyl)-2,3-dihydro-1,5-benzoxazepin-4(5H)-one
CAS 110579-27-6C10H8F3NO2
N-(3,3-Dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)-3,3-dimethylbutanamide chemical structure, C17H24N2O3, CAS 921817-28-9
N-(3,3-Dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)-3,3-dimethylbutanamide
CAS 921817-28-9C17H24N2O3
N-(3,3-Dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)isobutyramide chemical structure, C15H20N2O3, CAS 921777-32-4
N-(3,3-Dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)isobutyramide
CAS 921777-32-4C15H20N2O3
(S)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one hydrochloride chemical structure, C9H11ClN2O2, CAS 99197-91-8
(S)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one hydrochloride
CAS 99197-91-8C9H11ClN2O2
(S)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one chemical structure, C9H10N2O2, CAS 199613-85-9
(S)-7-Amino-6,7-dihydro-9H-5-oxa-9-aza-benzocyclohepten-8-one
CAS 199613-85-9C9H10N2O2
(S)-tert-Butyl (4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)carbamate chemical structure, C14H18N2O4, CAS 99197-80-5
(S)-tert-Butyl (4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)carbamate
CAS 99197-80-5C14H18N2O4
(2S,3S)-3-Amino-2-methyl-3,5-dihydro-2H-1,5-benzoxazepin-4-one chemical structure, C10H12N2O2, CAS 639478-68-5
(2S,3S)-3-Amino-2-methyl-3,5-dihydro-2H-1,5-benzoxazepin-4-one
CAS 639478-68-5C10H12N2O2
3-Amino-5-methyl-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one chemical structure, C10H12N2O2, CAS 1822340-52-2
3-Amino-5-methyl-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-one
CAS 1822340-52-2C10H12N2O2
3-Amino-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one hydrochloride chemical structure, C9H11ClN2O2, CAS 2044702-28-3
3-Amino-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one hydrochloride
CAS 2044702-28-3C9H11ClN2O2
1-(tert-Butyl)-3-(3,3,5-trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)urea chemical structure, C17H25N3O3, CAS 1172087-61-4
1-(tert-Butyl)-3-(3,3,5-trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)urea
CAS 1172087-61-4C17H25N3O3
1-(tert-Butyl)-3-(3,3-dimethyl-4-oxo-5-propyl-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)urea chemical structure, C19H29N3O3, CAS 1172899-49-8
1-(tert-Butyl)-3-(3,3-dimethyl-4-oxo-5-propyl-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)urea
CAS 1172899-49-8C19H29N3O3
1-(tert-Butyl)-3-(5-isopentyl-3,3-dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)urea chemical structure, C21H33N3O3, CAS 1170516-63-8
1-(tert-Butyl)-3-(5-isopentyl-3,3-dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-7-yl)urea
CAS 1170516-63-8C21H33N3O3
N,N-Dimethyl-2-(4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-5-yl)acetamide chemical structure, C13H16N2O3, CAS 1089555-27-0
N,N-Dimethyl-2-(4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-5-yl)acetamide
CAS 1089555-27-0C13H16N2O3
N-(3,3,5-Trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)butyramide chemical structure, C16H22N2O3, CAS 921587-52-2
N-(3,3,5-Trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)butyramide
CAS 921587-52-2C16H22N2O3
N-(3,3,5-Trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)acetamide chemical structure, C14H18N2O3, CAS 921868-01-1
N-(3,3,5-Trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)acetamide
CAS 921868-01-1C14H18N2O3
N-(3,3,5-Trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)propionamide chemical structure, C15H20N2O3, CAS 921560-96-5
N-(3,3,5-Trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)propionamide
CAS 921560-96-5C15H20N2O3
N-(3,3,5-Trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)isobutyramide chemical structure, C16H22N2O3, CAS 921868-04-4
N-(3,3,5-Trimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)isobutyramide
CAS 921868-04-4C16H22N2O3