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Murcko scaffold

Ring system with 4 rings and 24 atoms

59 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
59
With full pages
14
Scaffold SMILES

O=C(Nc1ccc(-c2nc3ncccc3o2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(-c2nc3ncccc3o2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

2-Chloro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C19H12ClN3O2, CAS 330963-97-8
2-Chloro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 330963-97-8C19H12ClN3O2
3-Methyl-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H15N3O2, CAS 431927-51-4
3-Methyl-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 431927-51-4C20H15N3O2
3-Fluoro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C19H12FN3O2, CAS 314029-66-8
3-Fluoro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 314029-66-8C19H12FN3O2
3-Chloro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C19H12ClN3O2, CAS 313962-11-7
3-Chloro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 313962-11-7C19H12ClN3O2
3,4-Dimethyl-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O2, CAS 353465-32-4
3,4-Dimethyl-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 353465-32-4C21H17N3O2
3-Methoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H15N3O3, CAS 312633-31-1
3-Methoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 312633-31-1C20H15N3O3
3-Chloro-4-ethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H16ClN3O3, CAS 6026-49-9
3-Chloro-4-ethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 6026-49-9C21H16ClN3O3
5-Bromo-2-iodo-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C19H11BrIN3O2, CAS 303131-35-3
5-Bromo-2-iodo-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 303131-35-3C19H11BrIN3O2
3-Bromo-4-ethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H16BrN3O3, CAS 330470-12-7
3-Bromo-4-ethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 330470-12-7C21H16BrN3O3
3,4,5-Trimethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C22H19N3O5, CAS 312944-00-6
3,4,5-Trimethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 312944-00-6C22H19N3O5
2-Chloro-5-iodo-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C19H11ClIN3O2, CAS 328566-81-0
2-Chloro-5-iodo-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 328566-81-0C19H11ClIN3O2
3,4-Dimethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O4, CAS 314044-24-1
3,4-Dimethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 314044-24-1C21H17N3O4
3-Ethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O3, CAS 331866-54-7
3-Ethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 331866-54-7C21H17N3O3
3,5-Dimethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H17N3O4, CAS 6005-63-6
3,5-Dimethoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 6005-63-6C21H17N3O4
3,4,5-Triethoxy-N-[2-methyl-4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C26H27N3O5, CAS 709626-97-1
3,4,5-Triethoxy-N-[2-methyl-4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 709626-97-1C26H27N3O5
2-Chloro-N-[2-methyl-4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H14ClN3O2, CAS 709627-12-3
2-Chloro-N-[2-methyl-4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 709627-12-3C20H14ClN3O2
3-Ethoxy-N-[2-methyl-4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C22H19N3O3, CAS 709626-91-5
3-Ethoxy-N-[2-methyl-4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 709626-91-5C22H19N3O3
N-[4-([1,3]Oxazolo[4,5-b]pyridin-2-yl)phenyl]-3-propan-2-yloxybenzamide chemical structure, C22H19N3O3, CAS 433702-42-2
N-[4-([1,3]Oxazolo[4,5-b]pyridin-2-yl)phenyl]-3-propan-2-yloxybenzamide
CAS 433702-42-2C22H19N3O3
3,5-Dichloro-4-methoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C20H13Cl2N3O3, CAS 710284-99-4
3,5-Dichloro-4-methoxy-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 710284-99-4C20H13Cl2N3O3
N-[4-([1,3]Oxazolo[4,5-b]pyridin-2-yl)phenyl]-4-propan-2-yloxybenzamide chemical structure, C22H19N3O3, CAS 433329-85-2
N-[4-([1,3]Oxazolo[4,5-b]pyridin-2-yl)phenyl]-4-propan-2-yloxybenzamide
CAS 433329-85-2C22H19N3O3
2,3-Dichloro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C19H11Cl2N3O2, CAS 328251-14-5
2,3-Dichloro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 328251-14-5C19H11Cl2N3O2
4-(2-Methylpropoxy)-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C23H21N3O3, CAS 424794-54-7
4-(2-Methylpropoxy)-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 424794-54-7C23H21N3O3
4-Ethoxy-3-nitro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide chemical structure, C21H16N4O5, CAS 327053-31-6
4-Ethoxy-3-nitro-N-[4-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]benzamide
CAS 327053-31-6C21H16N4O5
3,5-Diethoxy-N-(4-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide chemical structure, C23H21N3O4, CAS 425388-34-7
3,5-Diethoxy-N-(4-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)benzamide
CAS 425388-34-7C23H21N3O4