Murcko scaffold
Ring system with 2 rings and 10 atoms
30 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 30
- With full pages
- 7
Scaffold SMILES
O=c1[nH]cnc2c1SCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]cnc2c1SCC2](/scaffold/VVIRWMXLQQPCJI-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 30 of 30 chemicals
![3-Ethyl-2-ethylsulfanyl-6-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C11H16N2OS2, CAS 851409-80-8](/s/PSBLLRNSAULUIY-UHFFFAOYSA-N.svg)
3-Ethyl-2-ethylsulfanyl-6-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one
CAS 851409-80-8C11H16N2OS2
![Methyl 2-((3-ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)butanoate chemical structure, C14H20N2O3S2, CAS 851409-84-2](/s/JOIHQIFABKMPAI-UHFFFAOYSA-N.svg)
Methyl 2-((3-ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)butanoate
CAS 851409-84-2C14H20N2O3S2
![Ethyl 2-[(3,6-dimethyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]butanoate chemical structure, C14H20N2O3S2, CAS 702665-80-3](/s/TWCMSFGHQBGZPJ-UHFFFAOYSA-N.svg)
Ethyl 2-[(3,6-dimethyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]butanoate
CAS 702665-80-3C14H20N2O3S2
![3-(2-Methoxyethyl)-6-methyl-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H16N2O2S2, CAS 851410-42-9](/s/XZKQETSUYCUKQJ-UHFFFAOYSA-N.svg)
3-(2-Methoxyethyl)-6-methyl-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
CAS 851410-42-9C11H16N2O2S2
![2-(Isopropylthio)-3,6-dimethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C11H16N2OS2, CAS 702665-76-7](/s/JPSKGOHATGRHNR-UHFFFAOYSA-N.svg)
2-(Isopropylthio)-3,6-dimethyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
CAS 702665-76-7C11H16N2OS2
![2-((3-Ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C11H15N3O2S2, CAS 851409-59-1](/s/KNGUFFVJCCNWSI-UHFFFAOYSA-N.svg)
2-((3-Ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 851409-59-1C11H15N3O2S2
![Ethyl 2-((3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetate chemical structure, C12H16N2O3S2, CAS 702665-78-9](/s/SHRXBRHATKUWIW-UHFFFAOYSA-N.svg)
Ethyl 2-((3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetate
CAS 702665-78-9C12H16N2O3S2
![2-Butylsulfanyl-3-ethyl-6-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C13H20N2OS2, CAS 851409-82-0](/s/VYDSILDCDBILRW-UHFFFAOYSA-N.svg)
2-Butylsulfanyl-3-ethyl-6-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one
CAS 851409-82-0C13H20N2OS2
![Methyl 2-((3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)butanoate chemical structure, C13H18N2O3S2, CAS 702665-81-4](/s/CWXHWZQFBXTFRT-UHFFFAOYSA-N.svg)
Methyl 2-((3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)butanoate
CAS 702665-81-4C13H18N2O3S2
![Methyl 2-[(3-ethyl-6-methyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]propanoate chemical structure, C13H18N2O3S2, CAS 851409-85-3](/s/DYKNZIPFCUGFRI-UHFFFAOYSA-N.svg)
Methyl 2-[(3-ethyl-6-methyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)sulfanyl]propanoate
CAS 851409-85-3C13H18N2O3S2
![Ethyl 2-((3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)propanoate chemical structure, C13H18N2O3S2, CAS 702665-79-0](/s/PSZOLPRNYXACCX-UHFFFAOYSA-N.svg)
Ethyl 2-((3,6-dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)propanoate
CAS 702665-79-0C13H18N2O3S2
![Ethyl 2-((3-ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetate chemical structure, C13H18N2O3S2, CAS 851409-83-1](/s/BFKFHWCLMTYDCA-UHFFFAOYSA-N.svg)
Ethyl 2-((3-ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetate
CAS 851409-83-1C13H18N2O3S2
![2-((3-(2-Methoxyethyl)-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C12H17N3O3S2, CAS 851410-24-7](/s/VEEDSIIMGREDBU-UHFFFAOYSA-N.svg)
2-((3-(2-Methoxyethyl)-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 851410-24-7C12H17N3O3S2
![3-Ethyl-6-methyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C12H18N2OS2, CAS 851409-81-9](/s/LNFDGQWRNWCWCE-UHFFFAOYSA-N.svg)
3-Ethyl-6-methyl-2-(propylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
CAS 851409-81-9C12H18N2OS2
![2-((3,6-Dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C10H13N3O2S2, CAS 688353-48-2](/s/IXXKLXBLNQSSFP-UHFFFAOYSA-N.svg)
2-((3,6-Dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 688353-48-2C10H13N3O2S2
![3-Methyl-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C8H10N2OS2, CAS 869075-69-4](/s/TYVDVMFEFOONAJ-UHFFFAOYSA-N.svg)
3-Methyl-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
CAS 869075-69-4C8H10N2OS2
![2-(Ethylthio)-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C9H12N2OS2, CAS 869075-70-7](/s/YJCPLTUVIRMEJV-UHFFFAOYSA-N.svg)
2-(Ethylthio)-3-methyl-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
CAS 869075-70-7C9H12N2OS2
![Methyl 2-((3-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetate chemical structure, C10H12N2O3S2, CAS 893362-89-5](/s/KYDZHCZVQVMGPS-UHFFFAOYSA-N.svg)
Methyl 2-((3-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetate
CAS 893362-89-5C10H12N2O3S2
![3-Ethyl-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C9H12N2OS2, CAS 869076-23-3](/s/AXSRPWPZOMDKCE-UHFFFAOYSA-N.svg)
3-Ethyl-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
CAS 869076-23-3C9H12N2OS2
![3-Ethyl-2-ethylsulfanyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C10H14N2OS2, CAS 869076-24-4](/s/MAADETFXNIJJNH-UHFFFAOYSA-N.svg)
3-Ethyl-2-ethylsulfanyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one
CAS 869076-24-4C10H14N2OS2
![Ethyl 2-((3-ethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetate chemical structure, C12H16N2O3S2, CAS 893369-87-4](/s/LPOSEUXVVVVGCN-UHFFFAOYSA-N.svg)
Ethyl 2-((3-ethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetate
CAS 893369-87-4C12H16N2O3S2
![3-(2-Methoxyethyl)-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one chemical structure, C10H14N2O2S2, CAS 893370-17-7](/s/RZGYZLNUXGPFLV-UHFFFAOYSA-N.svg)
3-(2-Methoxyethyl)-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4(3H)-one
CAS 893370-17-7C10H14N2O2S2
![2-Ethylsulfanyl-3-(2-methoxyethyl)-6,7-dihydrothieno[3,2-d]pyrimidin-4-one chemical structure, C11H16N2O2S2, CAS 869076-72-2](/s/AVTXYZVGRUQLEI-UHFFFAOYSA-N.svg)
2-Ethylsulfanyl-3-(2-methoxyethyl)-6,7-dihydrothieno[3,2-d]pyrimidin-4-one
CAS 869076-72-2C11H16N2O2S2
![2-((3-Methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide chemical structure, C9H11N3O2S2, CAS 869075-77-4](/s/YHUZPMDEOXHYKW-UHFFFAOYSA-N.svg)
2-((3-Methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide
CAS 869075-77-4C9H11N3O2S2
- 2-({3-Ethyl-4-oxo-3H,4H,6H,7H-thieno[3,2-d]pyrimidin-2-yl}sulfanyl)acetamide869076-31-3C10H13N3O2S2
- 2-((3,6-Dimethyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-methylacetamide921497-46-3C11H15N3O2S2
- 2-((3-Ethyl-6-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)-N-methylacetamide921497-73-6C12H17N3O2S2
- Methyl 2-((3-methyl-4-oxo-3,4,6,7-tetrahydrothieno[3,2-d]pyrimidin-2-yl)thio)propanoate893363-19-4C11H14N2O3S2
- 2-(Methylthio)-6,7-dihydrothieno[3,2-D]pyrimidin-4-ol139297-07-7C7H8N2OS2
- 6,7-Dimethyl-2-(methylthio)-6,7-dihydrothieno[3,2-d]pyrimidin-4-ol1197226-23-5C9H12N2OS2
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