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Murcko scaffold

Ring system with 3 rings and 15 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
11
With full pages
1
Scaffold SMILES

c1ccc(-c2nccc(C3CC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nccc(C3CC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

4-Chloro-2-phenyl-6-cyclopropylpyrimidine chemical structure, C13H11ClN2, CAS 1159821-88-1
4-Chloro-2-phenyl-6-cyclopropylpyrimidine
CAS 1159821-88-1C13H11ClN2
4-Amino-2-phenyl-6-cyclopropylpyrimidine chemical structure, C13H13N3, CAS 1159819-75-6
4-Amino-2-phenyl-6-cyclopropylpyrimidine
CAS 1159819-75-6C13H13N3
4-(4-Cyclopropyl-6-methylpyrimidin-2-yl)aniline chemical structure, C14H15N3, CAS 1272272-73-7
4-(4-Cyclopropyl-6-methylpyrimidin-2-yl)aniline
CAS 1272272-73-7C14H15N3
2-(4-Bromophenyl)-4-chloro-6-cyclopropylpyrimidine chemical structure, C13H10BrClN2, CAS 1274539-45-5
2-(4-Bromophenyl)-4-chloro-6-cyclopropylpyrimidine
CAS 1274539-45-5C13H10BrClN2
4-Cyclopropyl-2-(p-tolyl)pyrimidine-5-carboxylic acid chemical structure, C15H14N2O2, CAS 1284373-37-0
4-Cyclopropyl-2-(p-tolyl)pyrimidine-5-carboxylic acid
CAS 1284373-37-0C15H14N2O2
4-Cyclopropyl-2-(4-fluorophenyl)pyrimidine-5-carboxylic acid chemical structure, C14H11FN2O2, CAS 1280574-37-9
4-Cyclopropyl-2-(4-fluorophenyl)pyrimidine-5-carboxylic acid
CAS 1280574-37-9C14H11FN2O2
2-(4-Chlorophenyl)-4-cyclopropylpyrimidine-5-carboxylic acid chemical structure, C14H11ClN2O2, CAS 1284418-58-1
2-(4-Chlorophenyl)-4-cyclopropylpyrimidine-5-carboxylic acid
CAS 1284418-58-1C14H11ClN2O2
2-(2-Chlorophenyl)-4-cyclopropylpyrimidine-5-carboxylic acid chemical structure, C14H11ClN2O2, CAS 1283933-33-4
2-(2-Chlorophenyl)-4-cyclopropylpyrimidine-5-carboxylic acid
CAS 1283933-33-4C14H11ClN2O2
4-Chloro-2-(3-chlorophenyl)-6-cyclopropylpyrimidine chemical structure, C13H10Cl2N2, CAS 1405676-11-0
4-Chloro-2-(3-chlorophenyl)-6-cyclopropylpyrimidine
CAS 1405676-11-0C13H10Cl2N2
6-Cyclopropyl-2-phenylpyrimidine-4-carboxylic acid chemical structure, C14H12N2O2, CAS 1159502-30-3
6-Cyclopropyl-2-phenylpyrimidine-4-carboxylic acid
CAS 1159502-30-3C14H12N2O2
4-Chloro-6-cyclopropyl-2-(4-nitrophenyl)pyrimidine-5-carbonitrile chemical structure, C14H9ClN4O2, CAS 1628055-83-3
4-Chloro-6-cyclopropyl-2-(4-nitrophenyl)pyrimidine-5-carbonitrile
CAS 1628055-83-3C14H9ClN4O2