Murcko scaffold
N-Phenylpiperidine-1-carbothioamide scaffold
121 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 121
- With full pages
- 41
Scaffold SMILES
S=C(Nc1ccccc1)N1CCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 121 chemicals
![Methyl 5-{[(4-hydroxypiperidyl)thioxomethyl]amino}-3-(methoxycarbonyl)benzoate chemical structure, C16H20N2O5S, CAS 708246-17-7](/s/OCMYUZAFFSWQQC-UHFFFAOYSA-N.svg)
Methyl 5-{[(4-hydroxypiperidyl)thioxomethyl]amino}-3-(methoxycarbonyl)benzoate
CAS 708246-17-7C16H20N2O5S
Dimethyl 2-(4-carbamoylpiperidine-1-carbothioamido)terephthalate
CAS 831232-36-1C17H21N3O5S
![1-[(4-Butylphenyl)carbamothioyl]piperidine-4-carboxamide chemical structure, C17H25N3OS, CAS 627063-47-2](/s/JFRUWZWJZFINMM-UHFFFAOYSA-N.svg)
1-[(4-Butylphenyl)carbamothioyl]piperidine-4-carboxamide
CAS 627063-47-2C17H25N3OS
![Ethyl 1-[(4-butylphenyl)carbamothioyl]piperidine-4-carboxylate chemical structure, C19H28N2O2S, CAS 301177-26-4](/s/WRNWHPCXJQUWDM-UHFFFAOYSA-N.svg)
Ethyl 1-[(4-butylphenyl)carbamothioyl]piperidine-4-carboxylate
CAS 301177-26-4C19H28N2O2S
N-(4-Nitrophenyl)piperidine-1-carbothioamide
CAS 72551-42-9C12H15N3O2S
N-(2,4-Dimethylphenyl)-3-(hydroxymethyl)piperidine-1-carbothioamide
CAS 503037-79-4C15H22N2OS
N-(4-Chloro-2-methylphenyl)-3-methylpiperidine-1-carbothioamide
CAS 516459-97-5C14H19ClN2S
N-(2,4-Dimethylphenyl)-3-methylpiperidine-1-carbothioamide
CAS 502891-51-2C15H22N2S
![Methyl [4-({[3-(hydroxymethyl)piperidin-1-yl]carbonothioyl}amino)phenyl]acetate chemical structure, C16H22N2O3S, CAS 516458-77-8](/s/YRKCFMXLOGLBNR-UHFFFAOYSA-N.svg)
Methyl [4-({[3-(hydroxymethyl)piperidin-1-yl]carbonothioyl}amino)phenyl]acetate
CAS 516458-77-8C16H22N2O3S
N-(4-Fluorophenyl)-3-methylpiperidine-1-carbothioamide
CAS 457093-03-7C13H17FN2S
![Ethyl 1-{[4-(ethoxycarbonyl)phenyl]carbamothioyl}piperidine-3-carboxylate chemical structure, C18H24N2O4S, CAS 479387-67-2](/s/ZROHDLGSFNPGTL-UHFFFAOYSA-N.svg)
Ethyl 1-{[4-(ethoxycarbonyl)phenyl]carbamothioyl}piperidine-3-carboxylate
CAS 479387-67-2C18H24N2O4S
![Ethyl 1-[(4-fluorophenyl)carbamothioyl]piperidine-3-carboxylate chemical structure, C15H19FN2O2S, CAS 516459-50-0](/s/NKONYPDTYMCXDK-UHFFFAOYSA-N.svg)
Ethyl 1-[(4-fluorophenyl)carbamothioyl]piperidine-3-carboxylate
CAS 516459-50-0C15H19FN2O2S
N-(2,4-Dimethoxyphenyl)-3-methylpiperidine-1-carbothioamide
CAS 516459-98-6C15H22N2O2S
![Ethyl 1-[(3,5-dimethoxyphenyl)carbamothioyl]piperidine-3-carboxylate chemical structure, C17H24N2O4S, CAS 516459-53-3](/s/ZPJUILHBZKAFKF-UHFFFAOYSA-N.svg)
Ethyl 1-[(3,5-dimethoxyphenyl)carbamothioyl]piperidine-3-carboxylate
CAS 516459-53-3C17H24N2O4S
![Ethyl 1-[(3-chloro-2-methylphenyl)carbamothioyl]piperidine-3-carboxylate chemical structure, C16H21ClN2O2S, CAS 516459-48-6](/s/OYRHOCSGNKHCRS-UHFFFAOYSA-N.svg)
Ethyl 1-[(3-chloro-2-methylphenyl)carbamothioyl]piperidine-3-carboxylate
CAS 516459-48-6C16H21ClN2O2S
![Ethyl 1-[(4-sulfamoylphenyl)carbamothioyl]piperidine-3-carboxylate chemical structure, C15H21N3O4S2, CAS 516459-55-5](/s/SPNMDKSZLVZZKB-UHFFFAOYSA-N.svg)
Ethyl 1-[(4-sulfamoylphenyl)carbamothioyl]piperidine-3-carboxylate
CAS 516459-55-5C15H21N3O4S2
N-(3,5-Dimethoxyphenyl)-3-(hydroxymethyl)piperidine-1-carbothioamide
CAS 516459-62-4C15H22N2O3S
![Ethyl 1-[(2,4-dimethoxyphenyl)carbamothioyl]piperidine-3-carboxylate chemical structure, C17H24N2O4S, CAS 516459-51-1](/s/FOLUQVSQXWMLSL-UHFFFAOYSA-N.svg)
Ethyl 1-[(2,4-dimethoxyphenyl)carbamothioyl]piperidine-3-carboxylate
CAS 516459-51-1C17H24N2O4S
N-(4-Fluorophenyl)-3-(hydroxymethyl)piperidine-1-carbothioamide
CAS 454231-94-8C13H17FN2OS
N-(4-Butylphenyl)-3-methylpiperidine-1-carbothioamide
CAS 516460-01-8C17H26N2S
N-(3-Chloro-2-methylphenyl)-3-(hydroxymethyl)piperidine-1-carbothioamide
CAS 516459-58-8C14H19ClN2OS
N-(3,5-Dimethoxyphenyl)-3-methylpiperidine-1-carbothioamide
CAS 516460-00-7C15H22N2O2S
![Ethyl 4-[(3-methylpiperidine-1-carbothioyl)amino]benzoate chemical structure, C16H22N2O2S, CAS 479514-42-6](/s/GCNKZQKBQCFFNG-UHFFFAOYSA-N.svg)
Ethyl 4-[(3-methylpiperidine-1-carbothioyl)amino]benzoate
CAS 479514-42-6C16H22N2O2S
N-(3,5-Dimethylphenyl)-3-methylpiperidine-1-carbothioamide
CAS 454663-42-4C15H22N2S
- Ethyl 1-[(4-chloro-2,5-dimethoxyphenyl)carbamothioyl]piperidine-3-carboxylate516459-57-7C17H23ClN2O4S
- Ethyl 1-[[4-(2-methoxy-2-oxoethyl)phenyl]carbamothioyl]piperidine-4-carboxylate516458-62-1C18H24N2O4S
- N-(4-Acetylphenyl)-2,6-dimethylpiperidine-1-carbothioamide701290-40-6C16H22N2OS
- N-(3,4-Dimethylphenyl)-2-(hydroxymethyl)piperidine-1-carbothioamide708243-60-1C15H22N2OS
- N-(2,4-Dichlorophenyl)-2-(hydroxymethyl)piperidine-1-carbothioamide454449-05-9C13H16Cl2N2OS
- N-(2,4-Dimethoxyphenyl)-2-methylpiperidine-1-carbothioamide708289-82-1C15H22N2O2S
- Ethyl 1-[(5-chloro-2-methoxyphenyl)carbamothioyl]piperidine-3-carboxylate708282-67-1C16H21ClN2O3S
- N-(3,5-Dimethoxyphenyl)-2-(hydroxymethyl)piperidine-1-carbothioamide708290-10-2C15H22N2O3S
- N-(3-Chloro-2-methylphenyl)-3-hydroxypiperidine-1-carbothioamide669756-30-3C13H17ClN2OS
- Methyl (4-{[(2-methylpiperidin-1-yl)carbonothioyl]amino}phenyl)acetate708998-36-1C16H22N2O2S
- N-(5-Chloro-2-methoxyphenyl)-2-(hydroxymethyl)piperidine-1-carbothioamide708999-35-3C14H19ClN2O2S
- N-(4-Chloro-2-methylphenyl)-2-methylpiperidine-1-carbothioamide708995-52-2C14H19ClN2S
- N-(4-Chloro-2,5-dimethoxyphenyl)-2-methylpiperidine-1-carbothioamide709005-64-1C15H21ClN2O2S
- Dimethyl 2-({[3-(hydroxymethyl)-1-piperidinyl]carbonothioyl}amino)terephthalate830353-69-0C17H22N2O5S
- Dimethyl 2-[(3-ethoxycarbonylpiperidine-1-carbothioyl)amino]benzene-1,4-dicarboxylate717830-01-8C19H24N2O6S
- Ethyl 1-({[4,5-dimethoxy-2-(methoxycarbonyl)phenyl]amino}carbonothioyl)-4-piperidinecarboxylate831216-62-7C19H26N2O6S
- Methyl 2-(3-(hydroxymethyl)piperidine-1-carbothioamido)-4,5-dimethoxybenzoate831233-34-2C17H24N2O5S
- Methyl 2-({[4-(ethoxycarbonyl)piperidyl]thioxomethyl}amino)-4-(methoxycarbonyl)benzoate831245-48-8C19H24N2O6S
- Ethyl 4-{[(3-cyanopiperidin-1-yl)carbonothioyl]amino}benzoate727683-15-0C16H19N3O2S
- N-(3,5-Difluorophenyl)-2-methylpiperidine-1-carbothioamide838867-15-5C13H16F2N2S
- 3-(Hydroxymethyl)-N-(3,4,5-trimethoxyphenyl)piperidine-1-carbothioamide890173-68-9C16H24N2O4S
- Ethyl 1-[(3,4,5-trimethoxyphenyl)carbamothioyl]piperidine-4-carboxylate890173-56-5C18H26N2O5S
- 4-Hydroxy-N-(3,4,5-trimethoxyphenyl)piperidine-1-carbothioamide879578-53-7C15H22N2O4S
- 1-[(3,4,5-Trimethoxyphenyl)carbamothioyl]piperidine-4-carboxamide879479-52-4C16H23N3O4S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals