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Murcko scaffold

1(2H)-Isoquinolinone, 3-phenyl- scaffold

60 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
60
With full pages
2
Scaffold SMILES

O=c1[nH]c(-c2ccccc2)cc2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1(2H)-Isoquinolinone, 3-phenyl- page
Murcko scaffold O=c1[nH]c(-c2ccccc2)cc2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

Benzoicc acid, 2-(1,2-dihydro-1-oxo-3-isoquinolinyl)- chemical structure, C16H11NO3, CAS 64077-18-5
Benzoicc acid, 2-(1,2-dihydro-1-oxo-3-isoquinolinyl)-
CAS 64077-18-5C16H11NO3
1(2H)-Isoquinolinone, 3-(4-chlorophenyl)- chemical structure, C15H10ClNO, CAS 124394-22-5
1(2H)-Isoquinolinone, 3-(4-chlorophenyl)-
CAS 124394-22-5C15H10ClNO
1(2H)-Isoquinolinone, 3-phenyl- chemical structure, C15H11NO, CAS 7115-13-1
1(2H)-Isoquinolinone, 3-phenyl-
CAS 7115-13-1C15H11NO
1(2H)-Isoquinolinone, 6,7-dimethoxy-3-(2-(2-hydroxyethyl)-4,5-dimethoxyphenyl)-2-methyl- chemical structure, C22H25NO6, CAS 136540-25-5
1(2H)-Isoquinolinone, 6,7-dimethoxy-3-(2-(2-hydroxyethyl)-4,5-dimethoxyphenyl)-2-methyl-
CAS 136540-25-5C22H25NO6
2-Amino-3-phenylisocarbostyril chemical structure, C15H12N2O, CAS 54613-38-6
2-Amino-3-phenylisocarbostyril
CAS 54613-38-6C15H12N2O
6-Methyl-3-phenyl-1(2H)-isoquinolinone chemical structure, C16H13NO, CAS 155694-70-5
6-Methyl-3-phenyl-1(2H)-isoquinolinone
CAS 155694-70-5C16H13NO
6,7-Dimethoxy-3-phenyl-1(2H)-isoquinolinone chemical structure, C17H15NO3, CAS 160856-44-0
6,7-Dimethoxy-3-phenyl-1(2H)-isoquinolinone
CAS 160856-44-0C17H15NO3
1(2H)-Isoquinolinone, 2,4-dimethyl-3-phenyl- chemical structure, C17H15NO, CAS 51089-64-6
1(2H)-Isoquinolinone, 2,4-dimethyl-3-phenyl-
CAS 51089-64-6C17H15NO
Draquinolol chemical structure, C24H30N2O4, CAS 67793-71-9
Draquinolol
CAS 67793-71-9C24H30N2O4
2-Methyl-3-phenylisoquinolin-1(2H)-one chemical structure, C16H13NO, CAS 34497-10-4
2-Methyl-3-phenylisoquinolin-1(2H)-one
CAS 34497-10-4C16H13NO
3-(3-Chlorophenyl)-2-methylisoquinolin-1(2H)-one chemical structure, C16H12ClNO, CAS 188674-77-3
3-(3-Chlorophenyl)-2-methylisoquinolin-1(2H)-one
CAS 188674-77-3C16H12ClNO
3-o-Tolylisoquinolin-1(2H)-one chemical structure, C16H13NO, CAS 54463-74-0
3-o-Tolylisoquinolin-1(2H)-one
CAS 54463-74-0C16H13NO
Ctk2C3550 chemical structure, C16H13NO2, CAS 62265-91-2
Ctk2C3550
CAS 62265-91-2C16H13NO2
3-(4-Chlorophenyl)-2-methylisoquinolin-1(2H)-one chemical structure, C16H12ClNO, CAS 142338-11-2
3-(4-Chlorophenyl)-2-methylisoquinolin-1(2H)-one
CAS 142338-11-2C16H12ClNO
1(2H)-Isoquinolinone, 7-(dimethylamino)-3-(3-methoxyphenyl)- chemical structure, C18H18N2O2, CAS 862469-60-1
1(2H)-Isoquinolinone, 7-(dimethylamino)-3-(3-methoxyphenyl)-
CAS 862469-60-1C18H18N2O2
6-Methoxy-3-phenyl-2H-isoquinolin-1-one chemical structure, C16H13NO2, CAS 630422-13-8
6-Methoxy-3-phenyl-2H-isoquinolin-1-one
CAS 630422-13-8C16H13NO2
3-(4-Methoxyphenyl)isoquinolin-1(2H)-one chemical structure, C16H13NO2, CAS 13670-91-2
3-(4-Methoxyphenyl)isoquinolin-1(2H)-one
CAS 13670-91-2C16H13NO2
6-Chloro-2-methyl-3-phenylisoquinolin-1(2H)-one chemical structure, C16H12ClNO, CAS 82632-49-3
6-Chloro-2-methyl-3-phenylisoquinolin-1(2H)-one
CAS 82632-49-3C16H12ClNO
3-p-Tolylisoquinolin-1(2H)-oneE chemical structure, C16H13NO, CAS 75040-00-5
3-p-Tolylisoquinolin-1(2H)-oneE
CAS 75040-00-5C16H13NO
3-(2-Hydroxyphenyl)isoquinolin-1(2H)-one chemical structure, C15H11NO2, CAS 143882-36-4
3-(2-Hydroxyphenyl)isoquinolin-1(2H)-one
CAS 143882-36-4C15H11NO2
5-Methoxy-3-phenyl-1(2H)-isoquinolinone chemical structure, C16H13NO2, CAS 129075-63-4
5-Methoxy-3-phenyl-1(2H)-isoquinolinone
CAS 129075-63-4C16H13NO2
3-(4-Hydroxyphenyl)-7-methoxy-2-methyl-1(2H)-isoquinolinone chemical structure, C17H15NO3, CAS 106579-62-8
3-(4-Hydroxyphenyl)-7-methoxy-2-methyl-1(2H)-isoquinolinone
CAS 106579-62-8C17H15NO3
3-[3-(Dimethylamino)phenyl]-6-methoxy-2H-isoquinolin-1-one chemical structure, C18H18N2O2, CAS 630423-77-7
3-[3-(Dimethylamino)phenyl]-6-methoxy-2H-isoquinolin-1-one
CAS 630423-77-7C18H18N2O2
3-[2-(Dimethylamino)phenyl]-6-methoxy-2H-isoquinolin-1-one chemical structure, C18H18N2O2, CAS 630423-72-2
3-[2-(Dimethylamino)phenyl]-6-methoxy-2H-isoquinolin-1-one
CAS 630423-72-2C18H18N2O2