Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 3 rings and 18 atoms

6 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 6
With full pages: 3

Scaffold SMILES

O=C1NC(c2ccco2)C(=Cc2cc[nH]c2)C1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1NC(c2ccco2)C(=Cc2cc[nH]c2)C1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Methyl 4-[[1-[3-(diethylamino)propyl]-2-(5-methylfuran-2-yl)-4,5-dioxopyrrolidin-3-ylidene]-hydroxymethyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate chemical structure, C25H33N3O6

Methyl 4-[[1-[3-(diethylamino)propyl]-2-(5-methylfuran-2-yl)-4,5-dioxopyrrolidin-3-ylidene]-hydroxymethyl]-3,5-dimethyl-1H-pyrrole-2-carboxylate

C₂₅H₃₃N₃O₆

Methyl 4-(1-(2-(diethylamino)ethyl)-2-(furan-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate chemical structure, C23H29N3O6, CAS 586984-49-8

Methyl 4-(1-(2-(diethylamino)ethyl)-2-(furan-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate

CAS 586984-49-8C₂₃H₂₉N₃O₆

Methyl 4-(1-(2-(dimethylamino)ethyl)-4-hydroxy-2-(5-methylfuran-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate chemical structure, C22H27N3O6, CAS 847368-60-9

Methyl 4-(1-(2-(dimethylamino)ethyl)-4-hydroxy-2-(5-methylfuran-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate

CAS 847368-60-9C₂₂H₂₇N₃O₆

Ethyl 4-(1-(2-(dimethylamino)ethyl)-2-(furan-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate chemical structure, C22H27N3O6, CAS 848920-00-3

Ethyl 4-(1-(2-(dimethylamino)ethyl)-2-(furan-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate

CAS 848920-00-3C₂₂H₂₇N₃O₆

Methyl 4-(1-(3-(dimethylamino)propyl)-2-(furan-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate chemical structure, C22H27N3O6, CAS 578745-20-7

Methyl 4-(1-(3-(dimethylamino)propyl)-2-(furan-2-yl)-4-hydroxy-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate

CAS 578745-20-7C₂₂H₂₇N₃O₆

Methyl 4-(1-(3-(diethylamino)propyl)-4-hydroxy-2-(5-methylfuran-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate chemical structure, C25H33N3O6, CAS 848206-11-1

Methyl 4-(1-(3-(diethylamino)propyl)-4-hydroxy-2-(5-methylfuran-2-yl)-5-oxo-2,5-dihydro-1H-pyrrole-3-carbonyl)-3,5-dimethyl-1H-pyrrole-2-carboxylate

CAS 848206-11-1C₂₅H₃₃N₃O₆