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Murcko scaffold

Ring system with 2 rings and 13 atoms

6 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
6
With full pages
3
Scaffold SMILES

O=C1NC=CC(c2ccncc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC=CC(c2ccncc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

5-Pyrimidinecarboxylic acid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(4-pyridinyl)-,2-propenyl ester chemical structure, C14H15N3O3, CAS 512840-51-6
5-Pyrimidinecarboxylic acid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(4-pyridinyl)-,2-propenyl ester
CAS 512840-51-6C14H15N3O3
5-Pyrimidinecarboxylic acid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(4-pyridinyl)-,1-methylethyl ester chemical structure, C14H17N3O3, CAS 367908-23-4
5-Pyrimidinecarboxylic acid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(4-pyridinyl)-,1-methylethyl ester
CAS 367908-23-4C14H17N3O3
Methyl 4-(3-fluoro-4-pyridinyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C12H12FN3O3, CAS 853313-94-7
Methyl 4-(3-fluoro-4-pyridinyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS 853313-94-7C12H12FN3O3
Ethyl 4-(3-fluoro-4-pyridinyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C13H14FN3O3, CAS 853314-24-6
Ethyl 4-(3-fluoro-4-pyridinyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS 853314-24-6C13H14FN3O3
Methyl 4-(3-chloro-4-pyridinyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C12H12ClN3O3, CAS 853316-79-7
Methyl 4-(3-chloro-4-pyridinyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS 853316-79-7C12H12ClN3O3
5-Pyrimidinecarboxylic acid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(4-pyridinyl)-,2-methoxyethyl ester chemical structure, C14H17N3O4, CAS 512840-69-6
5-Pyrimidinecarboxylic acid,1,2,3,4-tetrahydro-6-methyl-2-oxo-4-(4-pyridinyl)-,2-methoxyethyl ester
CAS 512840-69-6C14H17N3O4