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Murcko scaffold

Ring system with 4 rings and 23 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
8
With full pages
1
Scaffold SMILES

O=C(c1ccco1)N1N=C(c2ccco2)CC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccco1)N1N=C(c2ccco2)CC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

5-(4-Ethoxyphenyl)-1-(furan-2-carbonyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazole chemical structure, C20H18N2O4, CAS 899350-91-5
5-(4-Ethoxyphenyl)-1-(furan-2-carbonyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazole
CAS 899350-91-5C20H18N2O4
(5-(4-Chlorophenyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone chemical structure, C18H13ClN2O3, CAS 899350-89-1
(5-(4-Chlorophenyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
CAS 899350-89-1C18H13ClN2O3
Furan-2-yl(3-(furan-2-yl)-5-(2-hydroxy-3-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methanone chemical structure, C19H16N2O5, CAS 921142-30-5
Furan-2-yl(3-(furan-2-yl)-5-(2-hydroxy-3-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methanone
CAS 921142-30-5C19H16N2O5
(5-(4-Fluorophenyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone chemical structure, C18H13FN2O3, CAS 900134-13-6
(5-(4-Fluorophenyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
CAS 900134-13-6C18H13FN2O3
(5-(2,4-Dichlorophenyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone chemical structure, C18H12Cl2N2O3, CAS 899350-90-4
(5-(2,4-Dichlorophenyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
CAS 899350-90-4C18H12Cl2N2O3
Furan-2-yl(3-(furan-2-yl)-5-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methanone chemical structure, C18H14N2O4, CAS 927065-83-6
Furan-2-yl(3-(furan-2-yl)-5-(2-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methanone
CAS 927065-83-6C18H14N2O4
1-(Furan-2-carbonyl)-3-(furan-2-yl)-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazole chemical structure, C18H13N3O5, CAS 923227-29-6
1-(Furan-2-carbonyl)-3-(furan-2-yl)-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazole
CAS 923227-29-6C18H13N3O5
(5-(3-Bromophenyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone chemical structure, C18H13BrN2O3, CAS 1797955-16-8
(5-(3-Bromophenyl)-3-(furan-2-yl)-4,5-dihydro-1H-pyrazol-1-yl)(furan-2-yl)methanone
CAS 1797955-16-8C18H13BrN2O3