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Murcko scaffold

Ring system with 4 rings and 23 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
9
With full pages
6
Scaffold SMILES

O=C(c1ccco1)N1N=C(c2cccs2)CC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccco1)N1N=C(c2cccs2)CC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

(5-Bromofuran-2-yl)-[3-(4-methylphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]methanone chemical structure, C19H15BrN2O2S, CAS 361480-34-4
(5-Bromofuran-2-yl)-[3-(4-methylphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]methanone
CAS 361480-34-4C19H15BrN2O2S
(5-Bromofuran-2-yl)-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]methanone chemical structure, C19H15BrN2O3S, CAS 361480-29-7
(5-Bromofuran-2-yl)-[3-(4-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]methanone
CAS 361480-29-7C19H15BrN2O3S
5-(4-Fluorophenyl)-1-(2-furoyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole chemical structure, C18H13FN2O2S, CAS 438482-49-6
5-(4-Fluorophenyl)-1-(2-furoyl)-3-(2-thienyl)-4,5-dihydro-1H-pyrazole
CAS 438482-49-6C18H13FN2O2S
Ethyl 2-[2-[2-(furan-2-carbonyl)-5-thiophen-2-yl-3,4-dihydropyrazol-3-yl]phenoxy]acetate chemical structure, C22H20N2O5S, CAS 831211-48-4
Ethyl 2-[2-[2-(furan-2-carbonyl)-5-thiophen-2-yl-3,4-dihydropyrazol-3-yl]phenoxy]acetate
CAS 831211-48-4C22H20N2O5S
Furan-2-yl-[3-(2-hydroxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]methanone chemical structure, C18H14N2O3S, CAS 868214-27-1
Furan-2-yl-[3-(2-hydroxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]methanone
CAS 868214-27-1C18H14N2O3S
2-[1-(5-Nitrofuran-2-carbonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-5-yl]phenol chemical structure, C18H13N3O5S, CAS 876892-92-1
2-[1-(5-Nitrofuran-2-carbonyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazol-5-yl]phenol
CAS 876892-92-1C18H13N3O5S
Furan-2-yl-[3-(2-hydroxy-3-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]methanone chemical structure, C19H16N2O4S, CAS 871307-65-2
Furan-2-yl-[3-(2-hydroxy-3-methoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]methanone
CAS 871307-65-2C19H16N2O4S
1-(5-Bromofuran-2-carbonyl)-5-(4-bromophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole chemical structure, C18H12Br2N2O2S, CAS 361480-33-3
1-(5-Bromofuran-2-carbonyl)-5-(4-bromophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole
CAS 361480-33-3C18H12Br2N2O2S
[3-(3,4-Dimethoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone chemical structure, C20H18N2O4S, CAS 836625-35-5
[3-(3,4-Dimethoxyphenyl)-5-thiophen-2-yl-3,4-dihydropyrazol-2-yl]-(furan-2-yl)methanone
CAS 836625-35-5C20H18N2O4S