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Murcko scaffold

Ring system with 4 rings and 19 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
5
With full pages
4
Scaffold SMILES

c1cc2c3c(c(N4CCOCC4)nc2s1)CCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2c3c(c(N4CCOCC4)nc2s1)CCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

1-Amino-5-(4-morpholinyl)-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxamide chemical structure, C16H20N4O2S, CAS 118663-25-5
1-Amino-5-(4-morpholinyl)-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxamide
CAS 118663-25-5C16H20N4O2S
1-Amino-5-(4-morpholinyl)-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxylic acid ethyl ester chemical structure, C18H23N3O3S, CAS 54585-49-8
1-Amino-5-(4-morpholinyl)-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxylic acid ethyl ester
CAS 54585-49-8C18H23N3O3S
1-Amino-5-morpholin-4-yl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carbonitrile chemical structure, C16H18N4OS, CAS 118663-21-1
1-Amino-5-morpholin-4-yl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carbonitrile
CAS 118663-21-1C16H18N4OS
1-Amino-5-morpholin-4-yl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carbohydrazide chemical structure, C16H21N5O2S, CAS 489403-08-9
1-Amino-5-morpholin-4-yl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carbohydrazide
CAS 489403-08-9C16H21N5O2S
Methyl 1-amino-5-morpholino-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxylate chemical structure, C17H21N3O3S, CAS 371926-60-2
Methyl 1-amino-5-morpholino-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxylate
CAS 371926-60-2C17H21N3O3S