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Murcko scaffold

Ring system with 4 rings and 19 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
6
With full pages
3
Scaffold SMILES

c1cc2c3c(c(N4CCOCC4)nc2s1)COCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc2c3c(c(N4CCOCC4)nc2s1)COCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

1-Amino-8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carbonitrile chemical structure, C17H20N4O2S, CAS 204775-57-5
1-Amino-8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carbonitrile
CAS 204775-57-5C17H20N4O2S
8,8-Dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carbohydrazide chemical structure, C17H22N4O3S, CAS 329213-50-5
8,8-Dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carbohydrazide
CAS 329213-50-5C17H22N4O3S
1-Amino-8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxamide chemical structure, C17H22N4O3S, CAS 204775-60-0
1-Amino-8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxamide
CAS 204775-60-0C17H22N4O3S
Ethyl 8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-D]thieno[2,3-B]pyridine-2-carboxylate chemical structure, C19H24N2O4S, CAS 328072-67-9
Ethyl 8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-D]thieno[2,3-B]pyridine-2-carboxylate
CAS 328072-67-9C19H24N2O4S
Ethyl 1-amino-8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxylate chemical structure, C19H25N3O4S, CAS 175648-68-7
Ethyl 1-amino-8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxylate
CAS 175648-68-7C19H25N3O4S
1-Amino-N,N-dibutyl-8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxamide chemical structure, C25H38N4O3S, CAS 497241-66-4
1-Amino-N,N-dibutyl-8,8-dimethyl-5-morpholino-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxamide
CAS 497241-66-4C25H38N4O3S