Murcko scaffold
Ring system with 4 rings and 26 atoms
26 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 26
- Chemicals
- 26
- With full pages
- 5
Scaffold SMILES
O=C(Nc1cc2c(s1)CNCC2)c1ccc(S(=O)(=O)N2CCCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 26 of 26 chemicals
![N,6-dimethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C21H26N4O4S2, CAS 533891-60-0](/s/HRGBFHGHWZFYMQ-UHFFFAOYSA-N.svg)
N,6-dimethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 533891-60-0C21H26N4O4S2
![N-Methyl-6-propyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C23H30N4O4S2, CAS 533905-58-7](/s/WBGXHZAQUTWYAS-UHFFFAOYSA-N.svg)
N-Methyl-6-propyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 533905-58-7C23H30N4O4S2
![6-Isopropyl-N-methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C23H30N4O4S2, CAS 533907-69-6](/s/CCQRWHIHDOBVCL-UHFFFAOYSA-N.svg)
6-Isopropyl-N-methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 533907-69-6C23H30N4O4S2
![6-Acetyl-N-methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C22H26N4O5S2, CAS 534553-94-1](/s/URYLOMODUVYZNN-UHFFFAOYSA-N.svg)
6-Acetyl-N-methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 534553-94-1C22H26N4O5S2
![Ethyl 3-(methylcarbamoyl)-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C23H28N4O6S2, CAS 534556-02-0](/s/MWIOMZJMKLEHEV-UHFFFAOYSA-N.svg)
Ethyl 3-(methylcarbamoyl)-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 534556-02-0C23H28N4O6S2
![6-Ethyl-N-methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C22H28N4O4S2, CAS 533895-89-5](/s/KNHOBPRLUCGWAO-UHFFFAOYSA-N.svg)
6-Ethyl-N-methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 533895-89-5C22H28N4O4S2
![Ethyl 6-isopropyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C24H31N3O5S2, CAS 449768-21-2](/s/LYVNYHMTSWMPSD-UHFFFAOYSA-N.svg)
Ethyl 6-isopropyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449768-21-2C24H31N3O5S2
![Ethyl 6-methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C22H27N3O5S2, CAS 449766-94-3](/s/JZEXSQLNDHKHEE-UHFFFAOYSA-N.svg)
Ethyl 6-methyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449766-94-3C22H27N3O5S2
![Ethyl 6-ethyl-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate chemical structure, C23H29N3O5S2, CAS 449767-55-9](/s/WZOZIBXCMADRLN-UHFFFAOYSA-N.svg)
Ethyl 6-ethyl-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
CAS 449767-55-9C23H29N3O5S2
![Ethyl 3-carbamoyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C22H26N4O6S2, CAS 449782-09-6](/s/NCYUVMZWXFFWRG-UHFFFAOYSA-N.svg)
Ethyl 3-carbamoyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 449782-09-6C22H26N4O6S2
![6-Methyl-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide chemical structure, C20H24N4O4S2, CAS 449767-14-0](/s/MRJHEYUFJPRHES-UHFFFAOYSA-N.svg)
6-Methyl-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide
CAS 449767-14-0C20H24N4O4S2
![6-Ethyl 3-methyl 2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate chemical structure, C23H27N3O7S2, CAS 449770-64-3](/s/YHCABNCWBDTMOA-UHFFFAOYSA-N.svg)
6-Ethyl 3-methyl 2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate
CAS 449770-64-3C23H27N3O7S2
![Ethyl 3-cyano-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C22H24N4O5S2, CAS 681437-40-1](/s/GSOKVPFKIGGKDE-UHFFFAOYSA-N.svg)
Ethyl 3-cyano-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 681437-40-1C22H24N4O5S2
![6-Acetyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C21H24N4O5S2, CAS 449769-91-9](/s/JSSNHLLWUYDNFM-UHFFFAOYSA-N.svg)
6-Acetyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 449769-91-9C21H24N4O5S2
![N-(6-Acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide chemical structure, C21H22N4O4S2, CAS 681435-97-2](/s/GUVOAMQHPNBIRH-UHFFFAOYSA-N.svg)
N-(6-Acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)-4-pyrrolidin-1-ylsulfonylbenzamide
CAS 681435-97-2C21H22N4O4S2
![Methyl 5,5,7,7-tetramethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C24H31N3O5S2, CAS 489471-17-2](/s/KWQNVAVBUZBBNL-UHFFFAOYSA-N.svg)
Methyl 5,5,7,7-tetramethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 489471-17-2C24H31N3O5S2
![Diethyl 2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate chemical structure, C24H29N3O7S2, CAS 449781-64-0](/s/DTPZADRDCDNEDU-UHFFFAOYSA-N.svg)
Diethyl 2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate
CAS 449781-64-0C24H29N3O7S2
![Methyl 6-acetyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C22H25N3O6S2, CAS 449769-05-5](/s/MCPKYYBPYUNTQJ-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449769-05-5C22H25N3O6S2
![6-Isopropyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C22H28N4O4S2, CAS 449768-59-6](/s/WBWZUKUODVJRGU-UHFFFAOYSA-N.svg)
6-Isopropyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 449768-59-6C22H28N4O4S2
![N-(3-Cyano-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide chemical structure, C23H28N4O3S2, CAS 681438-91-5](/s/MZLNLKDTLKNGQJ-UHFFFAOYSA-N.svg)
N-(3-Cyano-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide
CAS 681438-91-5C23H28N4O3S2
![Ethyl 5,5,7,7-tetramethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C25H33N3O5S2, CAS 449783-01-1](/s/JRFDWXYRVYWVRS-UHFFFAOYSA-N.svg)
Ethyl 5,5,7,7-tetramethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449783-01-1C25H33N3O5S2
![Ethyl 6-acetyl-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate chemical structure, C23H27N3O6S2, CAS 449769-49-7](/s/PQKGNVKBPKQVFC-UHFFFAOYSA-N.svg)
Ethyl 6-acetyl-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
CAS 449769-49-7C23H27N3O6S2
![6-Propyl-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide chemical structure, C22H28N4O4S2, CAS 681181-52-2](/s/XHUFYFIIWQALCZ-UHFFFAOYSA-N.svg)
6-Propyl-2-[(4-pyrrolidin-1-ylsulfonylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide
CAS 681181-52-2C22H28N4O4S2
![N-(3-Cyano-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide hydrochloride chemical structure, C22H27ClN4O3S2, CAS 1215474-36-4](/s/YBIXTHWSBWIQRO-UHFFFAOYSA-N.svg)
N-(3-Cyano-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(pyrrolidin-1-ylsulfonyl)benzamide hydrochloride
CAS 1215474-36-4C22H27ClN4O3S2
- 6-Isopropyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride1215472-20-0C22H29ClN4O4S2
- 5,5,7,7-Tetramethyl-2-(4-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride1216672-67-1C23H31ClN4O4S2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C1NC(=O)C(Cc2ccc(OCc3nc4ccccc4[nH]3)cc2)S1](/scaffold/LDRYKEIIRGGZSI-UHFFFAOYSA-N/structure.svg)
